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The Tokushima University Seeds Collection

The Tokushima University Seeds Collection aims to promote new collaborations with industry and local governments by introducing overviews of research conducted at Tokushima University, along with related academic publications and intellectual property. 
Each research seed also includes its potential applications and commercialization prospects, making it a useful resource for exploring themes for joint research and new business initiatives.

Life Sciences / Engineering / Food Science

Life Sciences

No.	Title/Subtitle	Researcher(s)	Classification
L-01	An Innovative Immunization Technique for Efficient Induction of Antibodies Against Membrane Proteins  — Development of an Innovative Antibody Induction Platform Using Spleen-Targeted DDS Technology —	Hidenori Ando	Basic Research
L-02	Toward Widespread Clinical and Societal Adoption of Ultra-High-Sensitivity MRI — Nuclear Spin Polarization Technology via Eutectic and Co-Crystal Methods —	Munehiro Inukai	Basic Research
L-03	A Platform Technology to Accelerate Biopharmaceutical Development —    Toward Integrated Development of Protein Therapeutics, Production Cell Lines, and Bioprocesses —	Masayoshi Onitsuka	Basic Research
L-04	NMR-Based Technologies for Analyzing Biomolecule Dynamics — Investigating Protein Interactions, 3D Structures, and Dynamics in Solution at Atomic Resolution —	Tomohide Saio	Basic Research
L-05	Application of PET Imaging to Theranostics — From Non-Invasive “Seeing” Cancer to Truly “Diagnosing” It —	Tsuyoshi Tahara	Basic Research
L-06	Drug Repositioning for Chronic Pain — Efficacy of Tranilast in Trigeminal Neuropathic Pain —	Yoshizo Matsuka	Basic Research
L-07	Rapid Development Technology for Humanized Single-Domain Antibodies — A New Modality for Biosensor and Therapeutic Antibody Development —	Akikazu Murakami	Basic Research
L-08	Development of Novel Drug Discovery Technologies Based on the Epitranscriptome — Elucidation of New Homeostatic Mechanisms of Methylated RNA through Comprehensive Analyses and Exploration of Novel Drug Discovery Seeds —	Nazere Keyoumu Yuki Kuwano Hiroyuki Morino	Basic Research
L-09	Lysoplasmalogen as a Biomarker for Skin Inflammation and Barrier Function — A Novel Bioactive Lysophospholipid Involved in Skin Homeostasis and Chronic Inflammatory Skin Diseases —	Kei Yamamoto	Basic Research
L-10	Development of a Novel Clear Index System for Direct Composite Restoration — Standardizing High-Quality Direct Composite Restoration to Advance Minimally Invasive Dentistry —	Keiichiro Watanabe Keiichi Hosaka	Demonstration Research
L-11	A Non-Contact, Non-Invasive Technology for Intradermal Delivery of Macromolecules — Widespread Skin Penetration of Pharmaceuticals and Cosmetic Ingredients Using an “Electric Bath” —	Kentaro Kogure	Basic Research
L-12	Lipid Nanoparticle Formulation Technology Exhibiting High Translocation and Accumulation in Pancreatic Islets and Exocrine Pancreatic Tissue — Development of a Delivery Platform for Pancreas-Targeted Therapeutics —	Takanori Kanazawa	Basic Research
L-13	“Mimamoru-kun II”: Realizing System and Human Collaboration Between Dental Care, Medical Care, and Welfare/Care Services — An AI Engine Aimed at Behavioral Change Through Lifestyle Improvement Recommendations —	Kazumi Ozaki	Basic Research
L-14	Development of a Dental Caries Prevention Tool Using Cross-Modal Perception — A Predictive Experience of Toothache Caused by Dental Caries —	Takeshi Watanabe Naoya Tanigaki	Basic Research
L-15	Regulation of Fibrocytes by Clock Gene Inhibitors and Their Application to Cancer Therapy — Toward the Development of Novel Treatments to Overcome Resistance to Immunotherapy —	Atsushi Mitsuhashi Yasuhiko Nishioka	Basic Research
L-16	Manufacturing Method of Zwitterionic Compounds with Superior Protein Adsorption Resistance — Water-Soluble Antithrombotic Materials with Covalent Binding Capability to Metal and Glass Substrates —	Mikito Yasuzawa	Basic Research
L-17	Development of a VR-Based Tailor-made Toothbrushing Training Tool — A Self-Check Gamified System for Achieving Better Oral Health —	Takeshi Watanabe Kotone Yamashita Yuki Ishihara Kenji Yamamoto	Basic Research
L-18	Automated Image Analysis Technology for Quantifying the “Connectivity” of Liver Fibrosis Lesions ― Toward the Establishment of a Diagnostic Support System for Pathology ―	Mayuko Shimizu	Basic Research

Machinery / Environment / Energy / Civil Engineering / Architecture

No.	Title/Subtitle	Researcher(s)	Classification
E-01	Miniaturization and High-Power Output of Small Hydropower Generation Using a Contra-Rotating Rotor  — Effective Utilization of Energy Losses through a Pressure-Reducing Valve Equipped with an Inline Small Hydroturbine —	Toru Shigemitsu	Demonstration Research
E-02	High-Precision Positioning Control Technology for Pneumatic Actuators — Achieving Both Contact Safety and Nanometer-Scale Precision in Collaborative Robot Applications —	Masahiro Takaiwa	Demonstration Research
E-03	Development of a High-Accuracy, High-Speed Tsunami Simulator (JAGURS) — For Probabilistic Evaluation of Tsunami Events Toward Optimal Disaster countermeasures—	Toshitaka Baba	Demonstration Research
E-04	Application of Multimodal Emotion Estimation Technology for Supporting the Diagnosis of Mental Disorders — Achieving Emotion Estimation with Interpretability and Causal Inference —	Kazuyuki Matsumoto	Demonstration Research
E-05	Large-Area Nondestructive Inspection Technology Using Infrared Active Thermography  — Nondestructive Inspection Contributing to the Maintenance of Large-Scale Structures —	Masashi Ishikawa	Demonstration Research

Food / Agriculture, Forestry, and Fisheries

No.	Title/Subtitle	Researcher(s)	Classification
B-01	Research on Extending Shelf Life and Reducing Food Loss Using a Library of Food Spoilage Bacteria  — We aim to achieve rapid, low-cost microbial identification and the construction of a highly reliable library of food spoilage bacteria —	Fumiki Morimatsu	Basic Research
B-02	Visualization of Food Components by High-Sensitivity Mass Spectrometry Imaging — Contributing to Food Safety and Quality Improvement through Mass Spectrometry Imaging —	Hirofumi Enomoto	Applied Research

Last updated date：October 15, 2026