2021年度分子創薬化学セミナー（前期） - 徳島大学薬学部・大学院

第398回(2021. 7. 31)
担当者:山口真生
文献名:"Selective Synthesis of Z-Silyl Enol Ethers via Ni-Catalyzed Remote Functionalization of Ketones"
S. Guven, G. Kundu, A. WeBels, J. S. Ward, K. Rissanen, and F. Schoenebeck
J. Am. Chem. Soc., 143 (22), 8375-8380 (2021).

第397回(2021. 7. 17)
担当者:今橋縁
文献名:"Catalytic Enantioselective Synthesis of Morpholinones Enabled by Aza-Benzilic Ester Rearrangement"
Y. -P. He, H. Wu, Q. Wang, and J. Zhu
J. Am. Chem. Soc., 143 (19), 7320-7325 (2021).

第396回(2021. 7. 17)
担当者:藤井千恵子
文献名:"Catalytic Reductive Cross Coupling and Enantioselective Protonation of Olefins to Construct Remote Stereocenters for Azaarenes"
M. Kong, Y. Tan, X. Zhao, B. Qiao, C. -H. Tan, S. Cao, and Z. Jiang
J. Am. Chem. Soc., 143 (10), 4024-4031 (2021).

第395回(2021. 7. 10)
担当者:久保明音
文献名:"Fe-Catalyzed Anaerobic Mukaiyama-Type Hydration of Alkenes using Nitroarenes"
A. Bhunia, K. Bergander, C. G. Ganiliuc, and A. Studer
Angew. Chem. Int. Ed., 60 (15), 8313-8320 (2021).

第394回(2021. 7. 3)
担当者:舟田遥乃
文献名:"Enantioselective Silicon-Directed Nazarov Cyclization"
J. Cao, M. -Y. Hu, S. -Y. Liu, X. -Y. Zhang, S. -F. Zhu, and Q. -L. Zhou
J. Am. Chem. Soc., 143 (18), 6962-6968 (2021).

第393回(2021. 6. 26)
担当者:田原昌和
文献名:"[8 + 2] vs [4 + 2] Cycloadditions of Cyclohexadienamines to Tropone and Heptafulvenes – Mechanisms and Selectivities"
X. Chen, M. K. Thøgersen, L. Yang, R. F. Lauridsen, X. -S. Xue, K. A. Jørgensen, and K. N. Houk
J. Am. Chem. Soc., 143 (2), 934-944 (2021).

第392回(2021. 6. 26)
担当者:山田祥熙
文献名:"Synthesis of Polysubstituted Pyrroles through Electro-Oxidative Annulation of 1,3-Dicarbonyl Compounds and Primary Amines"
M. Xiong, X. Liang, Y. Zhou, and Y. Pan
J. Org. Chem., 86 (7), 4986-4993 (2021).

第391回(2021. 6. 19)
担当者:僧津真之介
文献名:"O-Isocyanates as Uncharged 1,3-Dipole Equivalents in [3 + 2] Cycloadditions"
M. A. Allen, R. A. Ivanovich, and A. M. Beauchemin
Angew. Chem. Int. Ed., 59 (51), 23188-23197 (2020).

第390回(2021. 6. 19)
担当者:馬場野瑛香
文献名:"Regioselective, Diastereoselective, and Enantioselective One-Pot Tandem Reaction Based on an in Situ Formed Reductant: Preparation of 2,3-Disubstituted 1,5-Benzodiazepine"
G. -F. Yang, G. -x. Li, J. Huang, D. -q. Fu, X. -k. Nie, X. Cui, J. -z. Zhao, and Z. Tang
J. Org. Chem., 86 (7), 5110-5119 (2021).

第389回(2021. 6. 5)
担当者:清水蘭愛
文献名:"Hexafluoroisopropanol-Promoted Haloamidation and Halolactonization of Unactiveted Alkenes"
C. Qi, G. Force, V. Gandon, and D. Lebaeuf
Angew. Chem. Int. Ed., 60 (2), 946-953 (2021).

第388回(2021. 6. 5)
担当者:中尾壮汰
文献名:"Regioselective [3 + 2] Cycloaddition Reaction of 3-Alkynoates with Seyferth-Gilbert Reagent"
Y. -T. Tian, F. -G. Zhang, and J. -A. Ma
J. Org. Chem., 86 (4), 3574-3582 (2021).

第387回(2021. 5. 22)
担当者:岡崎遼太郎
文献名:"Chiral Brønsted Acid from Chiral Phosphoric Acid Boron Complex and Water: Asymmetric Reduction of Indoles"
K. Yang, Y. Lou, C. Wang, L. -W. Qi, T. Fang, F. Zhang, H. Xu, L. Zhou, W. Li, G. Zhang, P. Yu, and Q. Song
Angew. Chem. Int. Ed., 59 (8), 3294-3299 (2020).

第386回(2021. 5. 22)
担当者:武居智之
文献名:"Synthesis of 1,3,4-Thiadiazoles and 1,4,2-Oxathiazoles from α-Enolic Dithioesters and Active 1,3-Dipoles"
B. Cheng, H. Li, J. Sun, X. Zhang, Y. He, H. Sun, W. Xu, T. Wang, and H. Zhai
J. Org. Chem., 86 (7), 5265-5273 (2021).

第385回(2021. 5. 15)
担当者:山口真生
文献名:"Morita-Baylis-Hillman-Type [3,3]-Rearrangement: Switching from Z- to E-Selective α-Arylation by New Rearrangement Partners"
L. Zhang, W. Bao, Y. Liang, W. Pan, D. Li, L. Kong, Z. -X. Wang, and B. Peng
Angew. Chem. Int. Ed., 60 (20), 11414-11422 (2021).

第384回(2021. 5. 15)
担当者:木場友太郎
文献名:"Cobalt-Catalyzed C-H Activation/Annulation of Benzamides with Fluorine-Containing Alkynes: A Route to 3- and 4-Fluoroalkylated Isoquinolines"
T. Kumon, J. Wu, M. Shimada, S. Yamada, T. Agou, H. Fukumoto, T. Kubota, G. B. Hammond, and T. Konno
J. Org. Chem., 86 (7), 5183-5196 (2021).

第383回(2021. 5. 8)
担当者:藤井千恵子
文献名:"Diversity-Oriented Synthesis of N,N,O-Trisubstituted Hydroxylamines from Alcohols and Amines by N-O Bond Formation"
J. Hill, A. A. Hettikankanamalage, and D. Crich
J. Am. Chem. Soc., 142 (35), 14820-14825 (2020).

第382回(2021. 5. 8)
担当者:久保明音
文献名:"Trifluoromethyl Sulfoxides: Reagents for Metal-Free C-H Trifluoromethylthiolation"
D. Wang, C. G. Carlton, M. Tayu, J. J. W. McDouall, G. J. P. Perry, and D. J. Procter
Angew. Chem. Int. Ed., 59 (37), 15918-15922 (2020).

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