2022年度分子創薬化学セミナー（前期） - 徳島大学薬学部・大学院

第425回 (2022. 7. 30)
担当者: 堀越拳
文献名:"Asymmetric Total Synthesis of Antibiotic Elansolid A"
L.-L. Wang, Q. Yu, W. Zhang, S. Yang, L. Peng, L. Zhang, X.-N. Li, F. Gagosz, and A. Kirschning
J. Am. Chem. Soc., 144 (15), 6871–6881 (2022).

第424回 (2022. 7. 30)
担当者: 武居智之
文献名:"Carbene-Catalyzed Enantioselective Sulfonylation of Enone Aryl Aldehydes: A New Mode of Breslow Intermediate Oxidation"
R. Deng, S. Wu, C. Mou, J. Liu, P. Zheng, X. Zhang, and Y. R. Chi
J. Am. Chem. Soc., 144 (12), 5441–5449 (2022).

第423回 (2022. 7. 16)
担当者: 山田祥熙
文献名:"Catalysis with Diboron(4)/Pyridine: Application to the Broad-Scope [3 + 2] Cycloaddition of Cyclopropanes and Alkenes"
Z. Ding, Z. Liu, Z. Wang, T. Yu, M. Xu, J. Wen, K. Yang, H. Zhang, L. Xu, and P. Li
J. Am. Chem. Soc., 144 (19), 8870–8882 (2022).

第422回 (2022. 7. 16)
担当者: 武居智之
文献名:"Borane-Catalyzed C3-Alkylation of Pyridines with Imines, Aldehydes, or Ketones as Electrophiles"
Z. Liu, J.-H. He, M. Zhang, Z.-J. Shi, H. Tang, X.-Y. Zhou, J.-J. Tian, and X.-C. Wang
J. Am. Chem. Soc., 144 (11), 4810–4818 (2022).

第421回 (2022. 6. 25)
担当者: 竹原未来子
文献名:"Bifunctional Iminophosphorane-Catalyzed Enantioselective Sulfa-Michael Addition to Unactivated α,β-Unsaturated Amides"
D. Rozsar, M. Formica, K. Yamazaki, T. A. Hamlin, and D. J. Dixon
J. Am. Chem. Soc., 144 (2), 1006–1015 (2022).

第420回 (2022. 6. 25)
担当者: 松浦拓美
文献名:"One-Pot anti-Michael Regio- and Stereoselective Hydroamination of Activated N-Allenamides"
M. Hourtoule, Y. Zheng, A. Perfetto, D. Luise, I. Ciofini, and L. Miesch
J. Org. Chem., 87 (8), 5404–5411 (2022).

第419回 (2022. 6. 18)
担当者: 岡本麻里衣
文献名:"Enabling Reductive C–N Cross-Coupling of Nitroalkanes and Boronic Acids by Steric Design of P(III)/P(V)=O Catalysts"
G. Li, Y. Kanda, S. Y. Hong, and A. T. Radosevich
J. Am. Chem. Soc., 144 (18), 8242–8248 (2022).

第418回 (2022. 6. 18)
担当者: 平澤萌
文献名:"Water Mediated Direct Thioamidation of Aldehydes at Room Temperature"
A. Gupta, J. K. Vankar, J. P. Jadav, and G. N. Gururaja
J. Org. Chem., 87 (5), 2410–2420 (2022).

第417回 (2022. 6. 11)
担当者: 山口真生
文献名:"Palladium-Catalyzed Regiodivergent Synthesis of 1,3-Dienyl and Allyl Esters from Propargyl Esters"
M. Dai, Z. Sun, and L.-A. Chen
Angew. Chem. Int. Ed., 61 (23), e202203835 (2022).

第416回 (2022. 6. 11)
担当者: 倉橋沙希
文献名:"Synthesis of α-Tropolones through Autoxidation of Dioxole-Fused Cycloheptatrienes"
A. J. Berkowitz, and R. P. Murelli
J. Org. Chem., 87 (7), 4499–4507 (2022).

第415回 (2022. 6. 4)
担当者: 藤井千恵子
文献名:"Synthesis of Silacyclic Dipeptides: Peptide Elongation at Both N- and C-Termini of Dipeptide"
T. Hattori, and H. Yamamoto
J. Am. Chem. Soc., 144 (4), 1758–1765 (2022).

第414回 (2022. 7. 2)
担当者: 乾龍太郎
文献名:"Synthesis of 2,2-Disubstituted Dihydro-1,4-benzothiazines from Morita–Baylis–Hillman Ketones by an Oxidative Cyclization"
A. K. Jha, R. Kumari, and S. Easwar
J. Org. Chem., 87 (9), 5760–5772 (2022).

第413回 (2022. 5. 21)
担当者: 久保明音
文献名:"Synthesis of Axially Chiral N-Arylindoles via Atroposelective Cyclization of Ynamides Catalyzed by Chiral Brønsted Acids"
Z.-S. Wang, L.-J. Zhu, C.-T. Li, B.-Y. Liu, X. Hong, and L.-W. Ye
Angew. Chem. Int. Ed., 61 (20), e202201436 (2022).

第412回 (2022. 5. 21)
担当者: 芦川由大
文献名:"Effect of Terminal Alkylation of Aryl and Heteroaryl Hydrazines in the Fischer Indole Synthesis"
M. A. Schmidt
J. Org. Chem., 87 (4), 1941–1960 (2022).

第411回 (2022. 5. 14)
担当者: 山田祥熙
文献名:"Copper-Catalyzed Regiodivergent and Enantioselective Hydrosilylation of Allenes"
J.-L. Xu, Z.-Y. Xu, Z.-L. Wang, W.-W. Ma, X.-Y. Sun, Y. Fu, and Y.-H. Xu
J. Am. Chem. Soc., 144 (12), 5535–5542 (2022).

その他の分子創薬化学セミナー * Molecular Medicinal Chemistry Seminar