平成29年度分子創薬化学セミナー(前期) - 徳島大学薬学部・大学院

第307回(2017. 7. 8)
担当者:関和雅
文献名:"Ruthenium-Catalyzed Cycloisomerization of 2-Alkynylanilides: Synthesis of 3-Substituted Indoles by 1,2-Carbon Migration"
T. Watanabe, Y. Mutoh, and S. Saito
J. Am. Chem. Soc., 139 (23), 7749-7752 (2017).

第306回(2017. 7. 8)
担当者:島袋友岐
文献名:"α-Halo Amides as Competent Latent Enolates: Direct Catalytic Asymmetric Mannich-Type Reaction"
B. Sun, P. V. Balaji, N. Kumagai, and M. Shibasaki
J. Am. Chem. Soc., 139 (24), 8295-8301 (2017).

第305回(2017. 7. 1)
担当者:岸本采乃
文献名:"A Reagent-Controlled Phospha-Michael Addition Reaction of Nitroalkenes with Bifunctional N-Heterocyclic Phosphine (NHP)-Thioureas"
H. Huang, J. Palmas, and J. Y. Kang
J. Org. Chem., 81 (23), 11932-11939 (2016).

第304回(2017. 7. 1)
担当者:堀越拳
文献名:"Determination of the Absolute Configuration and a Practical Chiral Synthesis of 5-[5-(1-Methylethoxy)pyridin-2-yl]-5-methylimidazolidine-2,4-dione as a Novel Liver X Receptor β-Selective Agonist"
M. Koura, H. Sumida, K. Shibuya, and S. Ohba
Synthesis, 49 (9), 2074-2080 (2017).

第303回(2017. 6. 24)
担当者:足立歩
文献名:"Salen-Based Covalent Organic Framework"
L.-H. Li, X.-L. Feng, X.-H. Cui, Y.-X. Ma, S.-Y. Ding, and W. Wang
J. Am. Chem. Soc., 139 (17), 6042-6045 (2017).

第302回(2017. 6. 24)
担当者:伊勢谷怜史
文献名:"Olefination of N-Sulfinylimines under Mild Conditions"
S. Dhara, and C. E. Diesendruck
Eur. J. Org. Chem., 1184-1190 (2017).

第301回(2017. 6. 17)
担当者:梶矢真由
文献名:"A Mild and Ligand-Free Ni-Catalyzed Silylation via C-OMe Cleavage"
C. Zarate, M. Nakajima, and R. Martin
J. Am. Chem. Soc., 139 (3), 1191-1197 (2017).

第300回(2017. 6. 17)
担当者:白川怜王奈
文献名:"Metal-Free Synthesis of 2,4,6-Trisubstituted Pyridines via Iodine-Initiated Reaction of Methyl Aryl Ketones with Amines under Neat Heating"
H. Xu, J. -C. Zeng, F. -J. Wang, and Z. Zhang
Synthesis, 49 (8), 1879-1883 (2017).

第299回(2017. 6. 10)
担当者:祥瑞知美
文献名:"β-Carboline Amides as Intrinsic Directing Groups for C(sp²)-H Functionalization"
H. M.-F. Viart, A. Bachmann, W. Kayitare, and R. Sarpong
J. Am. Chem. Soc., 139 (3), 1325-1329 (2017).

第298回(2017. 6. 10)
担当者:関和雅
文献名:"Ligandless Palladium-Catalyzed Reductive Carbonylation of Aryl Iodides under Ambient Conditions"
W. Han, B. Liu, J. Chen, and Q. Zhou
Synlett, 28 (7), 835-840 (2017).

第297回(2017. 5. 20)
担当者:仲村明人
文献名:"Accessing Both Retention and Inversion Pathways in Stereospecific, Nickel-Catalyzed Miyaura Borylations of Allylic Pivalates"
Q. Zhou, H. D. Srinivas, S. Zhang, and M. P. Watson
J. Am. Chem. Soc., 138 (36), 11989-11995 (2016).

第296回(2017. 5. 20)
担当者:島袋友岐
文献名:"Kinetic Resolution of β-Sulfonyl Ketones through Enantioselective β-Elimination using a Cation-Binding Polyether Catalyst"
L. Li, Y. Liu, Y. Peng, L. Yu, X. Wu, and H. Yan
Angew. Chem. Int. Ed., 55 (1), 331-335 (2016).

第295回(2017. 5. 13)
担当者:戸口宗尚
文献名:"Redox-Neutral α-Arylation of Alkyl Nitriles with Aryl Sulfoxides: A Rapid Electrophilic Rearrangement"
L. Shang, Y. Chang, F. Luo, J.-N. He, X. Huang, L. Zhang, L. Kong, K. Li, and B. Peng
J. Am. Chem. Soc., 139 (11), 4211-4217 (2017).

第294回(2017. 5. 13)
担当者:岸本采乃
文献名:"Metal-Free Synthesis of C-4 Substituted Pyridine Derivatives Using Pyridine-boryl Radicals via a Radical Addition/Coupling Mechanism: A Combined Computational and Experimental Study"
G. Wang, J. Cao, L. Gao, W. Chen, W. Huang, X. Cheng, and S. Li
J. Am. Chem. Soc., 139 (10), 3904-3910 (2017).

第293回(2017. 5. 6)
担当者:小田幸弘
文献名:"Cu-Catalyzed Sequential Dehydrogenation-Conjugate Addition for β-Functionalization of Saturated Ketones: Scope and Mechanism"
X. Jie, Y. Shang, X. Zhang, and W. Su
J. Am. Chem. Soc., 138 (17), 5623-5633 (2016).

第292回(2017. 5. 6)
担当者:鑛隆一郎
文献名:"Catalytic Synthesis of ''Super'' Linear Alkenyl Arenes Using an Easily Prepared Rh(I) Catalyst"
M. S. Webster-Gardiner, J. Chen, B. A. Vaughan, B. A. McKeown, W. Schinski, and T. B. Gunnoe
J. Am. Chem. Soc., 139 (15), 5474-5480 (2017).

その他の分子創薬化学セミナー * Molecular Medicinal Chemistry Seminar