平成27年度分子創薬化学セミナー(前期) - 徳島大学薬学部・大学院

第258回(2015. 09. 12)
担当者:藤原亮
文献名:"Ruthenium-Catalyzed Formal Dehydrative [4 + 2] Cycloaddition of Enamides and Alkynes for the Synthesis of Highly Substituted Pyridines: Reaction Development and Mechanistic Study"
J. Wu, W. Xu, Z.-X. Yu, and J. Wang
J. Am. Chem. Soc., 137 (29), 9489-9496 (2015).

第257回(2015. 09. 05)
担当者:杉村聡
文献名:"Biomimetic Total Synthesis of (-)-Penibruguieramine A Using Memory of Chirality and Dynamic Kinetic Resolution"
J. H. Kim, S. Lee, and S. Kim
Angew. Chem. Int. Ed., 54 (37), 10875-10878 (2015).

第256回(2015. 07. 11)
担当者:仲村明人
文献名:"Asymmetric Robinson-Type Annulation Reaction between β-Ketoamides and α,β-Unsaturated Ketones"
Y.-m. Huang, C.-w. Zheng, and G. Zhao
J. Org. Chem., 80 (8), 3798-3805 (2015).

第255回(2015. 07. 11)
担当者:戸口宗尚
文献名:"Catalytic Enantioselective Allenoate-Alkene [2 + 2] Cycloadditions"
M. L. Conner, Y. Xu, and M. K. Brown
J. Am. Chem. Soc., 137 (10), 3482-3485 (2015).

第254回(2015. 07. 04)
担当者:辻駿佑
文献名:"Where is the Oxygen? Structural Analysis of α-Humulene Oxidation Products by the Crystalline Sponge Method"
N. Zigon, M. Hoshino, S. Yoshioka, Y. Inokuma, and M. Fujita
Angew. Chem. Int. Ed., 54 (31), 9033-9037 (2015).

第253回(2015. 07. 04)
担当者:祥瑞知美
文献名:"Concise Three-Step Strategy for the Synthesis of 2-Benzoxepin-3(1H)-ones"
H. Madhurima, J. Krishna, and G. Satyanarayana
Synthesis, 47 (9), 1245-1254 (2015).

第252回(2015. 06. 27)
担当者:田中一江
文献名:"Reaction Mechanism of the Anomalous Formal Nucleophilic Borylation of Organic Halides with Silylborane: Combined Theoretical and Experimental Studies"
R. Uematsu, E. Yamamoto, S. Maeda, H. Ito, and T. Taketsugu
J. Am. Chem. Soc., 137 (12), 4090-4099 (2015).

第251回(2015. 06. 27)
担当者:柴田菜央
文献名:"Organocatalyzed Enantioselective Allylation of Isatins by Using a Chiral Amino Alcohol Derived Squaramide as Catalyst"
D. Ghosh, N. Gupta, S. H. R. Abdi, S. Nandi, N. H. Khan, R. I. Kureshy, and H. C. Bajaj
Eur. J. Org. Chem., (13), 2801-2806 (2015).

第250回(2015. 06. 13)
担当者:尾花潤
文献名:"A General Synthesis of Sphinganines through Multicomponent Catalytic Asymmetric Aziridination"
M. Mukherjee, Y. Zhou, A. K. Gupta, Y. Guan, and W. D. Wulff
Eur. J. Org. Chem., (7), 1386-1390 (2014).

第249回(2015. 06. 13)
担当者:井上大輔
文献名:"Metal-Mediated Reformatsky Reaction of Bromodifluoromethyl Ketone and Imine"
C.-R. Cao, M. Jiang, and J.-T. Liu
Eur. J. Org. Chem., (5), 1144-1151 (2015).

第248回(2015. 06. 06)
担当者:仲村明人
文献名:"Cobalt-Bisoxazoline-Catalyzed Asymmetric Kumada Cross-Coupling of Racemic α-Bromo Esters with Aryl Grignard Reagents"
J. Mao, F. Liu, M. Wang, L. Wu, B. Zheng, S. Liu, J. Zhong, Q. Bian, and P. J. Walsh
J. Am. Chem. Soc., 136 (50), 17662-17668 (2014).

第247回(2015. 06. 06)
担当者:梶矢真由
文献名:"Reductive Cyclization and Petasis-Like Reaction for the Synthesis of Functionalized γ-Lactams"
P. Wu, M. Å. Petersen, A. E. Cohrt, R. Petersen, M. H. Clausen, and T. E. Nielsen
Eur. J. Org. Chem., (11), 2346-2350 (2015).

第246回(2015. 05. 30)
担当者:戸口宗尚
文献名:"Group Exchange between Ketones and Carboxylic Acids through Directing Group Assisted Rh-Catalyzed Reorganization of Carbon Skeletons"
Z.-Q. Lei, F. Pan, H. Li, Y. Li, X.-S. Zhang, K. Chen, X. Wang, Y.-X. Li, J. Sun, and Z.-J. Shi
J. Am. Chem. Soc., 137 (15), 5012-5020 (2015).

第245回(2015. 10. 24)
担当者:足立歩
文献名:"Total Synthesis of Laingolide A Diastereomers"
G. Pomey, and P. Phansavath
Synthesis, 47 (7), 1016-1023 (2015).

第244回(2015. 05. 16)
担当者:中尾允泰
文献名:"Catalytic Divergent Synthesis of 3H or 1H Pyrroles by [3 + 2] Cyclization of Allenoates with Activated Isocyanides"
J.-Y. Liao, P.-L. Shao, and Y. Zhao
J. Am. Chem. Soc., 137 (2), 628-631 (2015).

第243回(2015. 05. 09)
担当者:藤原亮
文献名:"Highly Enantioselective Nickel-Catalyzed Intramolecular Reductive Cyclization of Alkynones"
W. Fu, M. Nie, A. Wang, Z. Cao and W. Tang
Angew. Chem. Int. Ed., 54 (8), 2520-2524 (2015).

第242回(2015. 05. 02)
担当者:杉村聡
文献名:"Palladium-Catalyzed C-H Functionalization of Acyldiazomethane and Tandem Cross-Coupling Reactions"
F. Ye, S. Qu, L. Zhou, C. Peng, C. Wang, J. Cheng, M. L. Hossain, Y. Liu, Y. Zhang, Z.-X. Wang, and J. Wang
J. Am. Chem. Soc., 137 (13), 4435-4444 (2015).

第241回(2015. 05. 02)
担当者:松本知也
文献名:"Brønsted Acid-Catalyzed Intramolecular Nucleophilic Substitution of the Hydroxyl Group in Stereogenic Alcohols with Chrality Transfer"
A. Bunrit, C. Dahlstrand, S. K. Olsson, P. Srifa, G. Huang, A. Orthaber, P. J. R. Sjöberg, S. Biswas, F. Himo, and J. S. M. Samec
J. Am. Chem. Soc., 137 (14), 4646-4649 (2015).

その他の分子創薬化学セミナー * Molecular Medicinal Chemistry Seminar