平成30年度分子創薬化学セミナー(前期) - 徳島大学薬学部・大学院

第334回(2018. 7. 28)
担当者:仲村明人
文献名:"Phospholyl(borane) Amino Acids and Peptides: Stereoselective Synthesis and Fluorescent Properties with Large Stokes Shift"
M. Arribat, E. Rémond, S. Clément, A. V. D. Lee, and F. Cavelier
J. Am. Chem. Soc.,140 (3), 1028-1034 (2018).

第333回(2018. 9. 8)
担当者:野脇静
文献名:"One-Pot Catalyst-Free Domino Condensation/Intramolecular 1,3-Dipolar Cycloaddition: Highly Stereoselective Access to Phosphadihydrocoumarin-Fused N,N-Bicy Pyrazolidin-3-ones"
M. Wu, J. Jiang, Z. Zhu, Q. Wang, and D. Kong
Synthesis,50 (1), 139-145 (2018).

第332回(2018. 7. 21)
担当者:戸口宗尚
文献名:"Breaking the Base Barrier: An Electron-Deficient Palladium Catalyst Enables the Use of a Common Soluble Base in C-N Coupling"
J. M. Dennis, N. A. White, R. Y. Liu, and S. L. Buchwald
J. Am. Chem. Soc.,140 (13), 4721-4725 (2018).

第331回(2018. 7. 21)
担当者:堀越拳
文献名:"Development of the Vinylogous Pictet-Spengler Cyclization and Total Synthesis of (±)-Lundurine A"
A. Nash, X. Qi, P. Maity, K. Owens, and U. K. Tambar
Angew. Chem. Int. Ed.,57 (23), 6888-6891 (2018).

第330回(2018. 7. 7)
担当者:白川怜王奈
文献名:"Radical Carbofluorination of Unactivated Alkenes with Fluoride Ions"
Z. Liu, H. Chen, Y. Lv, X. Tan, H. Shen, H.-Z. Yu, and C. Li
J. Am. Chem. Soc.,140 (19), 6169-6175 (2018).

第329回(2018. 7. 7)
担当者:伊勢谷怜史
文献名:"Palladium-Catalyzed Asymmetric Allylic Alkylation of 3-Substituted 1H-Indoles and Tryptophan Derivatives with Vinylcyclopropanes"
B. M. Trost, W.-J. Bai, C. Hohn, Y. Bai, and J. J. Cregg
J. Am. Chem. Soc.,140 (21), 6710-6717 (2018).

第328回(2018. 6. 30)
担当者:小田幸弘
文献名:"Site-Selective Switching Strategies to Functionalize Polyazines"
R. D. Dolewski, P. J. Fricke, and A. McNally
J. Am. Chem. Soc.,140 (25), 8020-8026 (2018).

第327回(2018. 6. 30)
担当者:鑛隆一郎
文献名:"Direct Access to Versatile Electrophiles via Catalytic Oxidative Cyanation of Alkenes"
D.-W. Gao, E. V. Vinogradova, S. K. Nimmagadda, J. M. Medina, Y. Xiao, R. M. Suciu, B. F. Cravatt, and K. M. Engle
J. Am. Chem. Soc., (2018) ASAP.

第326回(2018. 6. 16)
担当者:関和雅
文献名:"Total Synthesis of (+)- and (±)-Hosieine A"
Y.-W. Huang, K. Kong, and J. L. Wood
Angew. Chem. Int. Ed., 57 Early View (2018).

第325回(2018. 6. 16)
担当者:森美月
文献名:"One-Pot Synthesis of Highly Substituted Pyrroles by Three-Component Reactions of Donor-Acceptor Cyclopropanes, Salicylaldehydes, and Ammonium Acetate"
Z. Su, W. Gu, S. Qian, S. Xue, and C. Wang
Eur. J. Org. Chem., 2018 (8), 1019-1025 (2018).

第324回(2018. 6. 9)
担当者:島袋友岐
文献名:"Alkyl Ethers as Traceless Hydride Donors in Brønsted Acid Catalyzed Intramolecular Hydrogen Atom Transfer"
D. A. Gandamana, B. Wang, C. Tejo, B. Bolte, F. Gagosz, and S. Chiba
Angew. Chem. Int. Ed., 57 (21), 6181-6185 (2018).

第323回(2018. 6. 9)
担当者:原田紘之介
文献名:"Intramolecular Cycloaddition Approach to Fused Pyrazoles: Access to 4,5-Dihydro-2H-pyrazolo[4,3-c]quinolines, 2,8-Dihydroindeno[2,1-c]pyrazoles, a
ihydro-2H-benzo[e]indazoles"
M. Jash, B. Das, S. Sen, and C. Chowdhury

Synthesis, 50 (7), 1511-1520(2018).

第322回(2018. 5. 26)
担当者:岸本采乃
文献名:"A Transient Vinylphosphinidene via a Phosphirene-Phosphinidene Rearrangement"
L. L. Liu, J. Zhou, L. L. Cao, R. Andrews, R. L. Falconer, C. A. Russell, and D. W. Stephan
J. Am. Chem. Soc., 140 (1), 147-150 (2018).

第321回(2018. 5. 26)
担当者:大多和孝一
文献名:"A Concise and Stereoselective Total Synthesis of Pestalotioprolide C Using Ring-Closing Metathesis"
G. R. Kundoor, S. K. Battina, and P. R. Krishna
Synthesis, 50 (5), 1152-1158 (2018).

第320回(2018. 5. 19)
担当者:堀越拳
文献名:"Visible-Light-Mediated Aerobic Oxidation of N-Alkylpyridinium Salts under Organic Photocatalysis"
Y. Jin, L. Ou, H. Yang, and H. Fu
J. Am. Chem. Soc., 139 (40), 14237-14243 (2017).

第319回(2018. 5. 19)
担当者:井原嵩人
文献名:"Brønsted Acid Catalyzed Dehydrative Nucleophilic Substitution of C3-Substituted 2-Indolylmethanols with Azlactones"
C.-Y. Bian, D. Li, Q. Shi, G.-J. Mei, and F. Shi
Synthesis, 50 (2), 295-302 (2018).

第318回(2018. 5. 12)
担当者:白川怜王奈
文献名:"Ni-Catalyzed Carbon-Carbon Bond-Forming Reductive Amination"
C. Heinz, J. P. Lutz, E. M. Simmons, M. M. Miller, W. R. Ewing, and A. G. Doyle
J. Am. Chem. Soc., 140 (6), 2292-2300 (2018).

第317回(2018. 5. 12)
担当者:伊勢谷怜史
文献名:"Palladium and Lewis-Acid-Catalyzed Intramolecular Aminocyanation of Alkenes: Scope, Mechanism, and Stereoselective Alkene Difunctionalizations"
Z. Pan, S. Wang, J. T. Brethorst, and C. J. Douglas
J. Am. Chem. Soc., 140 (9), 3331-3338 (2018).

その他の分子創薬化学セミナー * Molecular Medicinal Chemistry Seminar