2020年度分子創薬化学セミナー - 徳島大学薬学部・大学院

第381回(2020. 12. 12)
担当者:中尾允泰
文献名:"Formyl MIDA Boronate: C1 Building Block Enables Straightforward Access to α-Functionalized Organoboron Derivatives"
Y. M. Ivon, I. V. Mazurenko, Y. O. Kuchkovska, Z. V. Voitenko, and O. O. Grygorenko
Angew. Chem. Int. Ed., 59 (41), 18016-18022 (2020).

第380回(2020. 12. 5)
担当者:堀越拳
文献名:"One-Step Synthesis of 2,5-Diaminoimidazoles and Total Synthesis of Methylglyoxal-Derived Imidazolium Crosslink (MODIC)"
V. R. Sabbasani, K. -P. Wang, M. D. Streeter, and D. A. Spiegel
Angew. Chem. Int. Ed., 58 (52), 18913-18917 (2019).

第379回(2020. 11. 21)
担当者:舟田遥乃
文献名:"Computational Design of Enhanced Enantioselectivity in Chiral Phosphoric Acid-Catalyzed Oxidative Desymmetrization of 1,3-Diol Acetals"
S. -S. Meng, P. Yu, Y. -Z. Yu, Y. Liang, K. N. Houk, and W. -H. Zheng
J. Am. Chem. Soc., 142 (18), 8506-8513 (2020).

第378回(2020. 11. 21)
担当者:僧津真之介
文献名:"Z-Selective α-Arylation of α,β-Unsaturated Nitriles via [3,3]-Sigmatropic Rearrangement"
M. Chen, Y. Liang, T. Dong, W. Liang, Y. Liu, Y. Zhang, X. Huang, L. Kong, Z. -X. Wang, and B. Peng
Angew. Chem. Int. Ed., accepted article (2020).

第377回(2020. 11. 19)
担当者:田原昌和
文献名:"Ketone Synthesis from Benzyldiboronates and Esters: Leveraging α-Boryl Carbanions for Carbon-Carbon Bond Formation"
B. Lee, and P. J. Chirik
J. Am. Chem. Soc., 142 (5), 2429-2437 (2020).

第376回(2020. 11. 19)
担当者:山口真生
文献名:"Catalytic Asymmetric [4+2] Cycloaddition of ortho-Alkenyl Naphthols/Phenols with ortho-Quinone Methides: Highly Stereoselective Synthesis of Chiral 2,3,4-Trisubstituted Chromanes"
S. Feng, B. Yang, T. Chen, R. Wang, Y. -H. Deng, and Z. Shao
J. Org. Chem., 85 (8), 5231-5244 (2020).

第375回(2020. 11. 7)
担当者:岡崎遼太郎
文献名:"Inverting External Asymmetric Induction via Selective Energy Transfer Catalysis: A Strategy to β-Chiral Phosphonate Antipodes"
C. Onneken, K. Bussmann, and R. Glimour
Angew. Chem. Int. Ed., 59 (1), 330-334 (2020).

第374回(2020. 11. 7)
担当者:藤井千恵子
文献名:"Sequential Regioselective Diorganochalcogenations of Imidazo[1,2-a]pyrimidines Using I2/H3PO4 in Dimethylsulfoxide"
A. R. Obah Kosso, Y. Kabri, J. Broggi, S. Redon, and P. Vanelle
J. Org. Chem., 85 (5), 3071-3081 (2020).

第373回(2020. 10. 17)
担当者:今橋縁
文献名:"Nickel-Catalyzed Enantioconvergent Reductive Hydroalkylation of Olefins with α-Heteroatom Phosphorus or Sulfur Alkyl Electrophiles"
S. -J. He, J. -W. Wang, Y. Li, Z. -Y. Xu, X. -X. Wang, X. Lu, and Y. Fu
J. Am. Chem. Soc., 142 (1), 214-221 (2020).

第372回(2020. 10. 17)
担当者:竹原未来子
文献名:"Synthesis and Rhodium(II)-Mediated Cascade Cyclopropanation/Rearrangement/Isomerization of Diazo 2,3,5-Trisubstituted Furans: The Construction of Penta-substituted Aromatic Compounds"
J. Zhang, Q. Yang, Y. Zhu, J. Wang, and G. Deng
J. Org. Chem., 85 (4), 2395-2405 (2020).

第371回(2020. 10. 10)
担当者:大多和孝一
文献名:"Convergent Catalytic Asymmetric Synthesis of Esters of Chiral Dialkyl Carbinols"
Z. -P. Yang, and G. C. Fu
J. Am. Chem. Soc., 142 (12), 5870-5875 (2020).

第370回(2020. 10. 10)
担当者:久保明音
文献名:"Regioselective Ring Expansion of 3-Ylideneoxindoles with Tosyldiazomethane (TsDAM): A Metal-Free and Greener Approach for the Synthesis of Pyrazolo-[1,5-c]quinazolines"
G. Ramu, Y. Tangella, S. Ambala, and B. N. Babu
J. Org. Chem., 85 (8), 5370-5378 (2020).

第369回(2020. 10. 3)
担当者:井原嵩人
文献名:"Highly Enantioselective Synthesis of Indazoles with a C3-Quaternary Chiral Center Using CuH Catalysis"
Y. Ye, I. Kevlishvili, S. Feng, P. Liu, and S. L. Buchwald
J. Am. Chem. Soc., 142 (23), 10550-10556 (2020).

第368回(2020. 10. 3)
担当者:岡本麻里衣
文献名:"Synthesis of Cyclohepta[b]indoles by (4 + 3) Cycloaddition of 2-Vinylindoles or 4H-Furo[3,2-b]indoles with Oxyallyl Cations"
V. Pirovano, E. Brambilla, A. Moretti, S. Rizzato, G. Abbiati, D. Nava, and E. Rossi
J. Org. Chem., 85 (5), 3265-3276 (2020).

その他の分子創薬化学セミナー * Molecular Medicinal Chemistry Seminar