平成21年度分子創薬化学セミナー(前期) - 徳島大学薬学部・大学院

第95回(2009. 09. 12)
担当者:矢野哲平
文献名:"Stereochemical Relay via Axially Chiral Styrenes: Asymmetric Synthesis of the Antibiotic TAN-1085"
K, Mori, K, Ohmori, and K. Suzuki
Angew. Chem. Int. Ed, 48 (31), 5633-5637 (2009).

第94回(2009. 09. 12)
担当者:廣山裕太
文献名:"Enantioselective α-Arylation of Aldehydes via Organo-SOMO Catalysis. An Ortho-Selective Arylation Reaction Based on an Open-Shell Pathway"
J. C. Conrad, J. Kong, B. N. Laforteza, and D. W. C. MacMillan
J. Am. Chem. Soc., 131 (33), 11640-11641 (2009).

第93回(2009. 07. 25)
担当者:久次米永子
文献名:"Asymmetric Synthesis of Indolines through Intramolecular Shifting of Aromatic Sulfinyl Groups. Role of the π,π-Stacking Interactions in these Unusual SNAr Processes"
J. L. G. Ruano, A. Parra, V. Marcos, C. del Pozo, S. Cataln, S. Monteagudo, S. Fustero, and A. Poveda
J. Am. Chem. Soc., 131 (26), 9432-9441 (2009).

第92回(2009. 07. 25)
担当者:中山ゆかり
文献名:"Discovery of Potent and Practical Antiangiogenic Agents Inspired by Cortistatin A"
B. Czak, L. Krti, A. Mammoto, D. E. Ingber, and E. J. Corey
J. Am. Chem. Soc., 131 (25), 9014-9019 (2009).

第91回(2009. 07. 11)
担当者:坂井亮介
文献名:"Water Overcomes Methyl Group Directing Effects in Epoxide-Opening Cascades"
C. J. Morten and T. F. Jamison
J. Am. Chem. Soc., 131 (19), 6678-6679 (2009).

第90回(2009. 07. 11)
担当者:嘉村真法
文献名:"Highly Efficient Asymmetric Synthesis of Sitagliptin"
K. B. Hansen, Y. Hsiao, F. Xu, N. Rivera, A. Clausen, M. Kubryk, S. Krska, T. Rosner, B. Simmons, J. Balsells, N. Ikemoto, Y. Sun, F. Spindler, C. Malan, E. J. J. Grabowski, and J. D. Armstrong, III
J. Am. Chem. Soc., 131 (25), 8798-8804 (2009).

第89回(2009. 07. 04)
担当者:森本晃允
文献名:"An Unexpected Bis-ligation of S-Nitrosothiols"
J. Zhang, H. Wang, and M. Xian
J. Am. Chem. Soc., 131 (11), 3854-3855 (2009).

第88回(2009. 07. 04)
担当者:堀部将史
文献名:"An Efficient and Highly Selective Synthesis of (Z)-Fluoroenol Phosphates from Hydroxy Difluorophosphonates"
P. Beier, R. Pohl, and A. V. Alexandrova
Synthesis, (6), 957-962 (2009).

第87回(2009. 06. 27)
担当者:七瀧浩志
文献名:"C-H Bond Functionalization via Hydride Transfer: Lewis Acid Catalyzed Alkylation Reactions by Direct Intramolecular Coupling of sp3 C-H Bonds and Reactive Alkenyl Oxocarbenium Intermediates"
K. M. McQuaid and D. Sames
J. Am. Chem. Soc., 131 (2), 402-403 (2009).

第86回(2009. 06. 27)
担当者:河野紘志
文献名:"Mild Stereoselective Hydrohalogenation Leading to (Z)-Halopropenamides at Room Temperature"
L.e Feray, P. Perfetti, and M. P. Bertrand
Synlett, (1), 89-91 (2009).

第85回(2009. 06. 13)
担当者:時實梨衣
文献名:"Total Synthesis of the Sphingolipid Biosynthesis Inhibitor Fumonisin B1"
C. L. Pereira, Y.-H. Chen, and F. E. McDonald
J. Am. Chem. Soc., 131 (17), 6066-6067 (2009).

第84回(2009. 06. 13)
担当者:矢野哲平
文献名:"Stereocontrolled Synthesis of β-Amino Alcohols from Lithiated Aziridines and Boronic Esters"
F. Schmidt, F. Keller, E. Vedrenne, and V. K. Aggarwal
Angew. Chem. Int. Ed, 48 (6), 1149-1152 (2009).

第83回(2009. 06. 06)
担当者:山下大輔
文献名:"Palladium-Catalyzed Insertion of -Diazoesters into Vinyl Halides To Generate α,β-Unsaturated -Amino Esters"
R. Kudirka, S. K. J. Devine, C. S. Adams, D. L. Van Vranken
Angew. Chem. Int. Ed, 48 (20), 3677-3680 (2009).

第82回(2009. 06. 06)
担当者:廣山裕太
文献名:"Ag-Catalyzed Diastereo- and Enantioselective Vinylogous Mannich Reactions of α-Ketoimine Esters. Development of a Method and Investigation of its Mechanism"
L. C. Wieland, E. M. Vieira, M. L. Snapper, and A.r H. Hoveyda
J. Am. Chem. Soc., 131 (2), 570-576 (2009).

第81回(2009. 05. 30)
担当者:市川喬士
文献名:"Unusually Reactive and Selective Carbonyl Ylides for Three-Component Cycloaddition Reactions"
A. DeAngelis, M. T. Taylor, and J. M. Fox
J. Am. Chem. Soc., 131 (3), 1101-1105 (2009).

第80回(2009. 05. 30)
担当者:中山ゆかり
文献名:"Stereoselective Construction of Seven-Membered Rings with an All-Carbon Quaternary Center by Direct Tiffeneau-Demjanov-type Ring Expansion"
T. Hashimoto, Y. Naganawa, and Keiji Maruoka
J. Am. Chem. Soc., 131 (18), 6614-6617 (2009).

第79回(2009. 05. 16)
担当者:津村武史
文献名:"Site-Directed Asymmetric Quaternization of a Peptide Backbone at a C-Terminal Azlactone"
D. Uraguchi, Y. Asai, and T. Ooi
Angew. Chem. Int. Ed, 48 (4), 733-737 (2009).

第78回(2009. 05. 16)
担当者:坂井亮介
文献名:"A Meta-Selective Copper-Catalyzed CーH Bond Arylation"
R. J. Phipps and M. J. Gaunt
Science, 323 (5921), 1593-1597 (2009).

第77回(2009. 05. 09)
担当者:中尾允泰
文献名:"Palladium-Catalyzed Substitution of Allylic Fluorides"
A. Hazari, V. Gouverneur, and J. M. Brown
Angew. Chem. Int. Ed, 48 (7), 1296-1299 (2009).

第76回(2009. 05. 09)
担当者:嘉村真法
文献名:"Rhodium-Catalyzed Direct Oxidative Carbonylation of Aromatic C-H Bond with CO and Alcohols"
Z.-H. Guan, Z.-H. Ren, S. M. Spinella, S. Yu, Y.-M. Liang, and X. Zhang
J. Am. Chem. Soc., 131 (2), 729-733 (2009).

その他の分子創薬化学セミナー * Molecular Medicinal Chemistry Seminar