研究業績 - 徳島大学医学部・大学院

業績2025

（論文発表）

Furukawa T, Hara M, Nishida Y, Tanaka K, Shimanoe C, Iwasaka C, Otonari J, Ikezaki H, Nagayoshi M, Tamura T, Tamada Y, Okada R, Oze I, Ito H, Michihara N, Nakamura Y, Tanoue S, Koriyama C, Suzuki S, Otani T, Watanabe I, Tomida S, Kuriki K, Takashima N, Kadota A, Ishizu M, Watanabe T, Nakatochi M, Momozawa Y, Wakai K, Matsuo K for the J-MICC Study Group. Comparison of polygenic risk scores for type 2 diabetes developed from different ancestry groups. npj metabolic health and disease. 3(17), 2025. 10.1038/s44324-025-00059-0

Ishizu M, Watanabe T, Torii Y, Kita K, Matsuura A, Unohara T, Katsuura-Kamano S, Uemura H. Association between coffee and adiponectin according to the obesity status: A cross-sectional analysis of the Japan Multi-Institutional Collaborative Cohort Study in Tokushima, Japan. Nutr Metab Cardiovasc Dis. 2025. https://doi.org/10.1016/j.numecd.2025.104103

Yamamoto S, Koyanagi YN, Iwashita Y, Shinozaki T, Fujiwara Y, Sakakura N, Hara M, Nishina Y, Otonari J, Ikezaki H, Tanoue S, Koriyama C, Kasugai Y, Oze I, Koyama T, Tomida S, Michihata N, Nakamura Y, Suzuki S, Nakagawa-Senda H, Nagayoshi M, Kubo Y, Kato Y, Wakai K, Watanabe T, Ishizu M, Takashima N, Kadota A, Momozawa Y, Nakatochi M, Tamura T, Niimi A, Ito H, Matsuo K. Smoking Behavior-related Genetic Variants and Lung Cancer Risk in Japanese: an Assessment by Mediation Analysis. Carcinogenesis 2025. https://doi.org/10.1093/carcin/bgaf011

Matsui N, Tanaka K, Kokubun N, Hatanaka Y, Ishida M, Osaki Y, Watanabe T, Watanabe O, Matsuura E, Takashima H, Sato Y, Kuwabara S, Izumi Y. Prevalence, clinical profiles, and prognosis of Isaacs syndrome: A nationwide survey study in Japan. Journal of the Neurological Sciences 2025. https://doi.org/10.1016/j.jns.2025.123442

（学会発表）

渡邊毅 :
がんリスクにおける代謝表現型の意義,
令和6年度コホート・生体試料支援プラットフォーム若手支援研究成果発表会, 2025年2月.

渡邊毅, 藤井亮輔, 原倫世, 松浦朱里, 鳥居優花, 北佳穂里, 卯之原大治, 石津将 :
KCNQ1遺伝的多型を考慮したコーヒー摂取および栄養素パターンと高血糖との関係,
第35回日本疫学会学術総会, 2025年2月.

石津将, 鈴木麗子, 黒田暁生, 松久宗英 :
徳島県市町村国保特定健診・後期高齢者医療健診における心電図異常に関わる因子の後向き検討,
第35回日本疫学会学術総会, 2025年2月.

卯之原大治, 渡邊毅, 松浦朱里, 北佳穂里, 鳥居優花, 石津将 :
食事酸負荷と死亡率:J-MICC Study,
第35回日本疫学会学術総会, 2025年2月.

上村浩一, 釜野桜子, 石津将, 渡邊毅 :
月経状況や生殖歴と慢性炎症，インスリン抵抗性や血中アディポネクチン値との関連,
第35回日本疫学会学術総会, 2025年2月.

須磨紫乃, 勝浦-釜野桜子, 片岡宏介, 渡邊毅, 石津将 :
大豆食品摂取量が全死因死亡・死因別死亡に与える影響:J-MICC Study,
第35回日本疫学会学術総会, 2025年2月.

石津将, 渡邊毅 :
コーヒー摂取量と血清高分子量体アディポネクチン濃度の関連ー日本多施設共同コーホート研究徳島地区データー,
令和6年度四国公衆衛生研究発表会, 2025年2月.

予防医学分野業績2024

（論文発表）

Unohara T, Watanabe T, Arisawa K, Matsuura A, Kita K, Torii Y, Ishizu M, Katsuura-Kamano S, Nguyen TV, Otonari J, Ikezaki H, Tanaka K, Shimanoe C, Nagayoshi M, Kubo Y, Matsunaga T, Okada R, Oze I, Ito H, Michihata N, Nakamura Y, Tanoue S, Koriyama C, Suzuki S, Nishiyama T, Koyama T, Ozaki E, Kuriki K, Takashima N, Kondo K, Tamura T, Matsuo K for the J-MICC Study Group. Dietary acid load and mortality: Results from the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. Research Square (preprint) 2024. 医学部4年生(Student Lab)の卯之原さんと渡邊助教が中心となってまとめた、食事酸負荷と死亡率に関する論文です。現在Under Reviewですが、一足先にPreprintとして公開となりました。医学部3年生の松浦さん、1年生の北さん、鳥居さんのデビュー作です。https://doi.org/10.21203/rs.3.rs-5297181/v 2

Miyagawa N, Takashima N, Harada A, Kadota A, Kondo K, Miura K, Imaeda N, Goto C, Otonari J, Ikezaki H, Tanaka K, Shimanoe C, Nagayoshi M, Tamura T, Kubo Y, Kato Y, Koyanagi N. Y, Ito H, Michihata N, Nakamura Y, Tanoue S, Ibusuki R, Suzuki S, Nishiyama T, Ozaki E, Watanabe I, Kuriki K, Watanabe T, Ishizu M, Hishida A, Kita Y, Wakai K, Matsuo K, J-MICC Study Group. Dairy Intake and All-Cause, Cancer, and Cardiovascular Disease Mortality Risk in A Large Japanese Population: A 12-Year Follow-Up of the J-MICC Study. Journal of Atherosclerosis and Thrombosis. 2024. 慶應義塾大学の宮川尚子先生と滋賀医大の先生方が中心にまとめられた乳製品と死亡リスクの関連を検討した論文です。https://doi.org/10.5551/jat.65049

Watanabe T, Nguyen TV, Katsuura-Kamano S , Arisawa K, Ishizu M, Unohara T, Tanaka K, Shimanoe C, Nagayoshi M, Tamura T, Kubo Y, Kato Y, Oze I, Ito H, Michihata N, Nakamura Y, Tanoue S, Koriyama C, Suzuki S, Nakagawa-Senda H, Koyama T, Tomida S, Kuriki K, Takashima N, Harada A, Wakai K, Matsuo K for the J-MICC Study Group. The Significance of Comprehensive Metabolic Phenotypes in Cancer Risk: A Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. Cancer Research Communications. 2024. 当分野の大学院生だったNguyen Van Tienさんと渡邊が中心にまとめた研究です。また、医学部４年生(Student Lab)の卯之原大治さんのデビュー作でもあります。代謝表現型（肥満の有無と心血管リスク因子の有無によるグループ分け）と全がん、部位別がん罹患の関係性について検討しました。https://doi.org/10.1158/2767-9764.CRC-24-0249

Hori T, Aihara K, Watanabe T, Inaba K, Inaba K, Kaneko Y, Kawata S, Kawahito K, Kita H, Shimizu K, Hosoki M, Mori K, Kageji T, Uraoka H, Nakamura S. The Respiratory Adjusted Shock Index at Admission Is a Valuable Predictor of In-Hospital Outcomes for Elderly Emergency Patients with Medical Diseases at a Japanese Community General Hospital. Journal of Clinical Medicine. 2024; 13(16), 4866. 徳島県立海部病院の堀先生、実践地域診療・医科学分野の中村先生を中心にまとめられた研究です。10.3390/jcm13164866

Hara T, Watanabe T, Yamagami H, Miyataka K, Yasui S, Asai T, Kaneko Y, Mitsui Y, Masuda S, Kurahashi K, Otoda T, Yuasa T, Kuroda A, Endo I, Honda S, Kondo A, Matsuhisa M, Aihara K. Development of Liver Fibrosis Represented by the Fibrosis-4 Index Is a Specific Risk Factor for Tubular Injury in Individuals with Type 2 Diabetes. Biomedicines. 2024; 12(8):1789. 血液・内分泌代謝内科学分野の原倫世先生が中心となってまとめられた共同研究です。 10.3390/biomedicines12081789

Fujii R, Hishida A, Nakatochi M, Okumiyama H, Takashima N, Tsuboi Y, Suzuki K, Ikezaki H, Shimanoe C, Kato Y, Tamura T, Ito H, Michihata N, Tanoue S, Suzuki S, Kuriki K, Kadota A, Watanabe T, Momozawa Y, Wakai K, Matsuo K. Polygenic risk score for blood pressure and lifestyle factors with overall and CVD mortality: a prospective cohort study in a Japanese population. Hypertens Res. 2024. 10.1038/s41440-024-01766-9.

渡邊毅, 細川育子, 工藤景子, 新嶋祐一朗. 歯科治療の不快感を最小化する. メディカル・サイエンス・ダイジェスト. 2024; 50(8):34-36. 渡邊が治療時の不快感を抑制するVR、セラピアVR(株式会社xCura)を装着して、再生歯科治療学分野の細川先生、口腔外科学分野の工藤先生に歯科治療を受けた際の感想と、今後効果検証をどのように行っていくべきかについての考察をまとめたものです。

Kasahara C, Tamura T, Wakai K, Tamada Y, Kato Y, Kubo Y, Okada R, Nagayoshi M, Hishida A, Imaeda N, Goto C, Otonari J, Ikezaki H, Nishida Y, Shimanoe C, Oze I, Koyanagi YN, Nakamura Y, Kusakabe M, Nishimoto D, Shimoshikiryo I, Suzuki S, Watanabe M, Ozaki E, Omichi C, Kuriki K, Takashima N, Miyagawa N, Arisawa K, Katsuura-Kamano S, Takeuchi K, Matsuo K. Association between consumption of small fish and all-cause mortality among Japanese: the Japan Multi-Institutional Collaborative Cohort Study. Public Health Nutr. 2024;27(1):e135. 10.1017/S1368980024000831.

Koyanagi YN, Nakatochi M, Namba S, Oze I, Charvat H, Narita A, Kawaguchi T, Ikezaki H, Hishida A, Hara M, Takezaki T, Koyama T, Nakamura Y, Suzuki S, Katsuura-Kamano S, Kuriki K, Nakamura Y, Takeuchi K, Hozawa A, Kinoshita K, Sutoh Y, Tanno K, Shimizu A, Ito H, Kasugai Y, Kawakatsu Y, Taniyama Y, Tajika M, Shimizu Y, Suzuki E, Hosono Y, Imoto I, Tabara Y, Takahashi M, Setoh K, Matsuda K, Nakano S, Goto A, Katagiri R, Yamaji T, Sawada N, Tsugane S, Wakai K, Yamamoto M, Sasaki M, Matsuda F, Okada Y, Iwasaki M, Brennan P, Matsuo K. Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people. Sci Adv. 2024;10(4):eade2780. 10.1126/sciadv.ade2780.

Nagamine T, Watanabe T. The Catastrophic Perception of Pain in Burning Mouth Syndrome May be Associated with Sympathetic Tone as Indicated by the QTc Interval. Innov Clin Neurosci. 2024;21(1-3):8-9. PMC10941860

Nagamine T, Watanabe T, Toyofuku A. QTc Shortening on Electrocardiogram With Amitriptyline May Indicate No Effect on Pain Relief in Burning Mouth Syndrome. Clin Neuropharmacol. 2024;47(2):33-6. doi: 10.1097/WNF.0000000000000583.

Tomida S, Koyama T, Ozaki E, Takashima N, Morita M, Sakaguchi K, Naoi Y, Nishida Y, Hara M, Hishida A, Tamura T, Okada R, Kubo Y, Otonari J, Ikezaki H, Nakamura Y, Kusakabe M, Tanoue S, Koriyama C, Koyanagi YN, Ito H, Suzuki S, Otani T, Miyagawa N, Okami Y, Arisawa K, Watanabe T, Kuriki K, Wakai K, Matsuo K. Seven-plus hours of daily sedentary time and the subsequent risk of breast cancer: Japan Multi-Institutional Collaborative Cohort Study. Cancer Sci. 2024;115(2):611-22. 10.1111/cas.16020

（学会発表）

上村浩一, 勝浦-釜野桜子, 石津将, 渡邊毅 :
日本人女性における生殖関連要因と動脈スティフネスとの関連:J-MICC Study徳島地区調査,
第39回日本女性医学学会学術集会, 2024年11月.

上村浩一, 勝浦-釜野桜子, 石津将, 渡邊毅 :
出産回数や月経状況と動脈スティフネスとの関連:J-MICC Study徳島地区調査,
第83回日本公衆衛生学会総会, 2024年10月.

Watanabe T, Unohara T, Nagamine T. Nociplastic Pain in Denistry: A literature Review. IASP 2024 World Congress on Pain, Amsterdam, Netherlands, 2024. 渡邊が専門としていた口腔顔面痛の症状について、近年国際疼痛学会によって提唱された、新しい痛みのカテゴリー「痛覚変調性疼痛」という視点から考察し、今後の研究の方向性についてまとめたものです。

渡邊毅 :
コーヒー摂取と代謝表現型:J-MICC研究のベースラインデータを用いた横断研究,
令和5年度コホート・生体試料支援プラットフォーム若手支援研究成果発表会, 2024年2月.

釜野桜子, 石津将, 渡邊毅 :
出生体重と日本人中高年の不安特性との関連:J-MICC Study 徳島地区調査,
第34回日本疫学会学術総会, 2024年2月.

予防医学分野業績2023

（論文発表）

Nishimoto D, Ibusuki R, Shimoshikiryo I, Shibuya K, Tanoue S, Koriyama C, Takezaki T, Oze I, Ito H, Hishida A, Tamura T, Kato Y, Tamada Y, Nishida Y, Shimanoe C, Suzuki S, Nishiyama T, Ozaki E, Tomida S, Kuriki K, Miyagawa N, Kondo K, Arisawa K, Watanabe T, Ikezaki H, Otonari J, Wakai K, Matsuo K. Association between awareness of limiting food intake and all-cause mortality: A cohort study in Japan. J Epidemiol. 2023.

Nagamine T, Watanabe T. QTc interval and sympathetic tone in burning mouth syndrome. Brain & Heart. 2023;2(1):2016.

Kitaoka K, Miura K, Takashima N, Kadota A, Harada A, Nakamura Y, Kita Y, Yano Y, Tamura T, Nagayoshi M, Okada R, Kubo Y, Suzuki S, Nishiyama T, Tanoue S, Koriyama C, Kuriki K, Arisawa K, Katsuura-Kamano S, Nishida Y, Shimanoe C, Ozaki E, Matsui D, Ikezaki H, Otonari J, Oze I, Koyanagi YN, Nakamura Y, Kusakabe M, Wakai K, Matsuo K. Association between Dietary Patterns and Serum Low Density Lipoprotein Cholesterol in Japanese Women and Men: The Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. J Atheroscler Thromb. 2023;30(10):1427-1447.

Tsukamoto M, Hishida A, Tamura T, Nagayoshi M, Okada R, Kubo Y, Kato Y, Hamajima N, Nishida Y, Shimanoe C, Ibusuki R, Shibuya K, Takashima N, Nakamura Y, Kusakabe M, Nakamura Y, Koyanagi YN, Oze I, Nishiyama T, Suzuki S, Watanabe I, Matsui D, Otonari J, Ikezaki H, Katsuura-Kamano S, Arisawa K, Kuriki K, Nakatochi M, Momozawa Y, Takeuchi K, Wakai K, Matsuo K. GWAS of folate metabolism with gene-environment interaction analysis revealed the possible role of lifestyles in the control of blood folate metabolites in Japanese - the J-MICC Study. J Epidemiol. 2023.

Kurasawa S, Imaizumi T, Maruyama S, Tanaka K, Kubo Y, Nagayoshi M, Ikezaki H, Suzuki S, Koyama T, Koriyama C, Kadota A, Katsuura-Kamano S, Kuriki K, Wakai K, Matsuo K. Association of kidney function with cancer incidence and its influence on cancer risk of smoking: The Japan Multi-Institutional Collaborative Cohort Study. Int J Cancer. 2023;153(4):732-741.

Tamura T, Wakai K, Kato Y, Tamada Y, Kubo Y, Okada R, Nagayoshi M, Hishida A, Imaeda N, Goto C, Ikezaki H, Otonari J, Hara M, Tanaka K, Nakamura Y, Kusakabe M, Ibusuki R, Koriyama C, Oze I, Ito H, Suzuki S, Nakagawa-Senda H, Ozaki E, Matsui D, Kuriki K, Kondo K, Takashima N, Watanabe T, Katsuura-Kamano S, Matsuo K. Dietary Carbohydrate and Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study. J Nutr. 2023;153(8):2352-2368.

Hanyuda A, Goto A, Katagiri R, Koyanagi YN, Nakatochi M, Sutoh Y, Nakano S, Oze I, Ito H, Yamaji T, Sawada N, Iwagami M, Kadota A, Koyama T, Katsuura-Kamano S, Ikezaki H, Tanaka K, Takezaki T, Imoto I, Suzuki M, Momozawa Y, Takeuchi K, Narita A, Hozawa A, Kinoshita K, Shimizu A, Tanno K, Matsuo K, Tsugane S, Wakai K, Sasaki M, Yamamoto M, Iwasaki M. Investigating the association between glycaemic traits and colorectal cancer in the Japanese population using Mendelian randomisation. Sci Rep. 2023;13(1):7052.

Sakashita T, Nakamura Y, Sutoh Y, Shimizu A, Hachiya T, Otsuka-Yamasaki Y, Takashima N, Kadota A, Miura K, Kita Y, Ikezaki H, Otonari J, Tanaka K, Shimanoe C, Koyama T, Watanabe I, Suzuki S, Nakagawa-Senda H, Hishida A, Tamura T, Kato Y, Okada R, Kuriki K, Katsuura-Kamano S, Watanabe T, Tanoue S, Koriyama C, Oze I, Koyanagi YN, Nakamura Y, Kusakabe M, Nakatochi M, Momozawa Y, Wakai K, Matsuo K. Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population. Diabetol Int. 2023;14(2):188-198.

Watanabe T, Sieg M, Lunde SJ, Persson M, Taneja P, Baad-Hansen L, Pigg M, Vase L. Nocebo response in dentistry: A systematic review and meta-analysis of adverse events in analgesic trials of third molar removal. J Oral Rehabil. 2023;50(4):332-42. 10.1111/joor.13414.

Watanabe T, Arisawa K, Nguyen TV, Ishizu M, Katsuura-Kamano S, Hishida A, Tamura T, Kato Y, Okada R, Ibusuki R, Koriyama C, Suzuki S, Otani T, Koyama T, Tomida S, Kuriki K, Takashima N, Miyagawa N, Wakai K, Matsuo K. Coffee and metabolic phenotypes: A cross-sectional analysis of the Japan multi-institutional collaborative cohort (J-MICC) study. Nutr Metab Cardiovasc Dis. 2023;33(3):620-630. 10.1016/j.numecd.2022.12.019.

（学会発表）

渡邊毅 :
コーヒー摂取と代謝表現型:J-MICC研究のベースラインデータを用いた横断研究,
2023 年度科学研究費補助⾦「コホート・⽣体試料⽀援プラットフォーム」⽀援に係る会議⽇本多施設共同コーホート(J-MICC)研究2023 年度第2回全体会議, 2023年12月.

釜野桜子, 有澤孝吉, 石津将, 渡邊毅, TIEN VAN NGUYEN :
大豆製品およびイソフラボン摂取量と糖尿病罹患との関連:J-MICC Study,
第33回日本疫学会学術総会, 2023年2月.

渡邊毅, 有澤孝吉, Nguyen Van Tien, 石津将, 釜野桜子 :
コーヒー摂取と代謝表現型:J-MICC Studyのベースラインデータを用いた横断研究,
第33回日本疫学会学術総会, 2023年2月.

（論文発表）

Omichi C, Koyama T, Kadotani H, Ozaki E, Tomida S, Yoshida T, Otonari J, Ikezaki H, Hara M, Tanaka K, Tamura T, Nagayoshi M, Okada R, Kubo Y, Oze I, Matsuo K, Nakamura Y, Kusakabe M, Ibusuki R, Shibuya K, Suzuki S, Watanabe M, Kuriki K, Takashima N, Kadota A, Katsuura-Kamano S, Arisawa K, Takeuchi K, Wakai K. Irregular sleep and all-cause mortality: A large prospective cohort study. Sleep Health. 2022.

Sogawa R, Shimanoe C, Tanaka K, Hara M, Nishida Y, Furukawa T, Nagayoshi M, Hishida A, Kubo Y, Kato Y, Oze I, Ito H, Nakamura Y, Kusakabe M, Tanoue S, Koriyama C, Suzuki S, Otani T, Matsui D, Watanabe I, Kuriki K, Takashima N, Kadota A, Watanabe T, Arisawa K, Ikezaki H, Otonari J, Wakai K, Matsuo K. Sex- and age-specific all-cause mortality in insomnia with hypnotics: Findings from Japan multi-institutional Collaborative Cohort Study. Sleep Med. 2022;100:410-418.

Saita K, Sumitani M, Nishizawa D, Tamura T, Ikeda K, Wakai K, Sudo Y, Abe H, Otonari J, Ikezaki H, Takeuchi K, Hishida A, Tanaka K, Shimanoe C, Takezaki T, Ibusuki R, Oze I, Ito H, Ozaki E, Matsui D, Nakamura Y, Kusakabe M, Suzuki S, Nakagawa-Senda H, Arisawa K, Katsuura-Kamano S, Kuriki K, Kita Y, Nakamura Y, Momozawa Y, Uchida K. Genetic polymorphism of pleiotrophin is associated with pain experience in Japanese adults: Case-control study. Medicine (Baltimore). 2022;101(37):e30580.

井上徹, 渡邊毅, 石川賀代. 介護施設入所者におけるGeriatric Nutritional Risk Index, 血清アルブミン値, Body Mass Indexの評価と関連する因子について. 四国医学雑誌. 2022; 78(3-4), 95-102

Nguyen TV, Arisawa K, Uemura H, Imaeda N, Goto C, Katsuura-Kamano S. Association Between Nutrient Patterns and Fatty Liver Index: Baseline Survey of the Japan Multi-Institutional Collaborative Cohort Study in Tokushima, Japan. J Epidemiol. 2022;32(8):376-383.

Nakamura Y, Tamura T, Narita A, Shimizu A, Sutoh Y, Takashima N, Matsui K, Miyagawa N, Kadota A, Miura K, Otonari J, Ikezaki H, Hishida A, Nagayoshi M, Okada R, Kubo Y, Tanaka K, Shimanoe C, Ibusuki R, Nishimoto D, Oze I, Ito H, Ozaki E, Matsui D, Mikami H, Kusakabe M, Suzuki S, Watanabe M, Arisawa K, Katsuura-Kamano S, Kuriki K, Nakatochi M, Momozawa Y, Kubo M, Takeuchi K, Wakai K. A genome-wide association study on adherence to low-carbohydrate diets in Japanese. Eur J Clin Nutr. 2022;76(8):1103-1110.

Fujii R, Hishida A, Nakatochi M, Tsuboi Y, Suzuki K, Kondo T, Ikezaki H, Hara M, Okada R, Tamura T, Shimoshikiryo I, Suzuki S, Koyama T, Kuriki K, Takashima N, Arisawa K, Momozawa Y, Kubo M, Takeuchi K, Wakai K. Associations of Genome-Wide Polygenic Risk Score and Risk Factors With Hypertension in a Japanese Population. Circ Genom Precis Med. 2022;15(4):e003612.

Nguyen TV, Arisawa K, Katsuura-Kamano S, Ishizu M, Nagayoshi M, Okada R, Hishida A, Tamura T, Hara M, Tanaka K, Nishimoto D, Shibuya K, Koyama T, Watanabe I, Suzuki S, Nishiyama T, Kuriki K, Nakamura Y, Saito Y, Ikezaki H, Otonari J, Y NK, Matsuo K, Mikami H, Kusakabe M, Takeuchi K, Wakai K. Associations of metabolic syndrome and metabolically unhealthy obesity with cancer mortality: The Japan Multi-Institutional Collaborative Cohort (J-MICC) study. PLoS One. 2022;17(7):e0269550.

Iwame T, Matsuura T, Suzue N, Katsuura-Kamano S, Takao S, Iwase J, Sairyo K. One-year follow-up ultrasonographic study of the subchondral bone surface of the distal femoral epiphysis in children aged 9-11 years. J Pediatr Orthop B. 2022;31(2):e174-e179.

Watanabe T, Sieg M, Lunde SJ, Taneja P, Baad-Hansen L, Pigg M, Vase L. What is the nocebo effect and does it apply to dentistry?-A narrative review. J Oral Rehabil. 2022;49(5):586-91.

Matsunaga T, Kadomatsu Y, Tsukamoto M, Kubo Y, Okada R, Nagayoshi M, Tamura T, Hishida A, Takezaki T, Shimoshikiryo I, Suzuki S, Nakagawa H, Takashima N, Saito Y, Kuriki K, Arisawa K, Katsuura-Kamano S, Kuriyama N, Matsui D, Mikami H, Nakamura Y, Oze I, Ito H, Murata M, Ikezaki H, Nishida Y, Shimanoe C, Takeuchi K, Wakai K. Associations of breastfeeding history with metabolic syndrome and cardiovascular risk factors in community-dwelling parous women: The Japan Multi-Institutional Collaborative Cohort Study. PLoS One. 2022;17(1):e0262252.

Koga K, Hara M, Shimanoe C, Nishida Y, Furukawa T, Iwasaka C, Tanaka K, Otonari J, Ikezaki H, Kubo Y, Kato Y, Tamura T, Hishida A, Matsuo K, Ito H, Nakamura Y, Kusakabe M, Nishimoto D, Shibuya K, Suzuki S, Watanabe M, Ozaki E, Matsui D, Kuriki K, Takashima N, Kadota A, Arisawa K, Katsuura-Kamano S, Takeuchi K, Wakai K. Association of perceived stress and coping strategies with the renal function in middle-aged and older Japanese men and women. Sci Rep. 2022;12(1):291.

Furukawa T, Nishida Y, Hara M, Shimanoe C, Koga K, Iwasaka C, Higaki Y, Tanaka K, Nakashima R, Ikezaki H, Hishida A, Tamura T, Kato Y, Tamada Y, Matsuo K, Ito H, Mikami H, Kusakabe M, Ibusuki R, Shibuya K, Suzuki S, Nakagawa-Senda H, Ozaki E, Matsui D, Kuriki K, Nakamura Y, Kadota A, Arisawa K, Katsuura-Kamano S, Takeuchi K, Wakai K. Effect of the interaction between physical activity and estimated macronutrient intake on HbA1c: population-based cross-sectional and longitudinal studies. BMJ Open Diabetes Res Care. 2022;10(1).

Suzuki T, Nakamura Y, Doi Y, Narita A, Shimizu A, Imaeda N, Goto C, Matsui K, Kadota A, Miura K, Nakatochi M, Tanaka K, Hara M, Ikezaki H, Murata M, Takezaki T, Nishimoto D, Matsuo K, Oze I, Kuriyama N, Ozaki E, Mikami H, Nakamura Y, Watanabe M, Suzuki S, Katsuura-Kamano S, Arisawa K, Kuriki K, Momozawa Y, Kubo M, Takeuchi K, Kita Y, Wakai K. A genome-wide association study on confection consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort Study. Br J Nutr. 2021;126(12):1843-1851.

Takeuchi K, Naito M, Kawai S, Tsukamoto M, Kadomatsu Y, Kubo Y, Okada R, Nagayoshi M, Tamura T, Hishida A, Nakatochi M, Sasakabe T, Hashimoto S, Eguchi H, Momozawa Y, Ikezaki H, Murata M, Furusyo N, Tanaka K, Hara M, Nishida Y, Matsuo K, Ito H, Oze I, Mikami H, Nakamura Y, Kusakabe M, Takezaki T, Ibusuki R, Shimoshikiryo I, Suzuki S, Nishiyama T, Watanabe M, Koyama T, Ozaki E, Watanabe I, Kuriki K, Kita Y, Ueshima H, Matsui K, Arisawa K, Uemura H, Katsuura-Kamano S, Nakamura S, Narimatsu H, Hamajima N, Tanaka H, Wakai K. Study Profile of the Japan Multi-institutional Collaborative Cohort (J-MICC) Study. J Epidemiol. 2021;31(12):660-668.

予防医学分野業績2021

（論文発表）

Sakurako Katsuura-Kamano, Kokichi Arisawa, Hirokazu Uemura, Nguyen Van Tien, Takezaki Toshiro, Ibusuki Rie, Suzuki Sadao, Otani Takahiro, Okada Rieko, Kubo Yoko, Tamura Takashi, Hishida Asahi, Koyama Teruhide, Matsui Daisuke, Kuriki Kiyonori, Takashima Naoyuki, Miyagawa Naoko, Ikezaki Hiroaki, Matsumoto Yuji, Nishida Yuichiro, Shimanoe Chisato, Oze Isao, Matsuo Keitaro, Mikami Haruo, Kusakabe Miho, Takeuchi Kenji, Wakai Kenji and the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study: Association of skipping breakfast and short sleep duration with the prevalence of metabolic syndrome in the general Japanese population: baseline data from the Japan Multi-Institutional Collaborative Cohort Study, Preventive Medicine Reports (accepted), 2021.

Hara Megumi, Nishida Yuichiro, Tanaka Keitaro, Shimanoe Chisato, Koga Kayoko, Furukawa Takuma, Higaki Yasuki, Shinchi Koichi, Ikezaki Hiroaki, Murata Masayuki, Takeuchi Kenji, Tamura Takashi, Hishida Asahi, Tsukamoto Mineko, Kadomatsu Yuka, Matsuo Keitaro, Oze Isao, Haruo Mikami, Miho Kusakabe, Takezaki Toshiro, Ibusuki Rie, Suzuki Sadao, Nakagawa-Senda Hiroko, Matsui Daisuke, Koyama Teruhide, Kuriki Kiyonori, Takashima Naoyuki, Nakamura Yasuyuki, Kokichi Arisawa, Sakurako Katsuura-Kamano and Wakai Kenji: Moderate-to-vigorous physical activity and sedentary behavior are independently associated with renal function: a cross-sectional study, Journal of Epidemiology (accepted), 2021.

Mako Nagayoshi, Kenji Takeuchi, Yudai Tamada, Kato Yasufumi, Yoko Kubo, Rieko Okada, Takashi Tamura, Asahi Hishida, Jun Otonari, Hiroaki Ikezaki, Yuichiro Nishida, Chisato Shimanoe, Yuriko N. Koyanagi, Keitaro Matsuo, Mikami Haruo, Kusakabe Miho, Daisaku Nishimoto, Keiichi Shibuya, Sadao Suzuki, Takeshi Nishiyama, Etsuko Ozaki, Isao Watanabe, Kiyonori Kuriki, Naoyuki Takashima, Aya Kadota, Kokichi Arisawa, Sakurako Katsuura-Kamano, Kenji Wakai and the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study: Sex-specific Relationship between Stress Coping Strategies and All-Cause Mortality: Japan Multi-Institutional Collaborative Cohort Study, Journal of Epidemiology, 2021.

Yusuke Kawamura, Akiyoshi Nakayama, Seiko Shimizu, Yu Toyoda, Yuichiro Nishida, Asahi Hishida, Sakurako Katsuura-Kamano, Kenichi Shibuya, Takashi Tamura, Makoto Kawaguchi, Satoko Suzuki, Satoko Iwasawa, Hiroshi Nakashima, Rie Ibusuki, Hirokazu Uemura, Megumi Hara, Kenji Takeuchi, Tappei Takada, Masashi Tsunoda, Kokichi Arisawa, Toshiro Takezaki, Keitaro Tanaka, Kimiyoshi Ichida, Kenji Wakai, Nariyoshi Shinomiya and Hirotaka Matsuo: A Proposal For Practical Diagnosis Of Renal Hypouricemia: Evidenced From Genetic Studies Of Nonfunctional Variants Of URAT1/SLC22A12 Among 30,685 Japanese Individuals, Biomedicines, Vol.9, No.8, 2021.

Yora Nindita, Masahiro Nakatochi, Rie Ibusuki, Ippei Shimoshikiryo, Daisaku Nishimoto, Keiichi Shimatani, Toshiro Takezaki, Hiroaki Ikezaki, Masayuki Murata, Megumi Hara, Yuichiro Nishida, Takashi Tamura, Asahi Hishida, Mako Nagayoshi, Rieko Okada, Keitaro Matsuo, Hidemi Ito, Haruo Mikami, Yohko Nakamura, Takahiro Otani, Sadao Suzuki, Teruhide Koyama, Etsuko Ozaki, Kiyonori Kuriki, Naoyuki Takashima, Naoko Miyagawa, Kokichi Arisawa, Sakurako Katsuura-Kamano, Yukihide Momozawa, Michiaki Kubo, Kenji Takeuchi, Kenji Wakai and the Japan Multi-Institutional Collaborative Cohort Study Group: Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-Cholesterol Levels in J-MICC Study Participants, Journal of Epidemiology, 2021.

Toshiyuki Iwame, Tetsuya Matsuura, Naoto Suzue, Sakurako Katsuura-Kamano, Shoichiro Takao, Jyoji Iwase and Koichi Sairyo: One-year follow-up ultrasonographic study of the subchondral bone surface of the distal femoral epiphysis in children aged 9-11 years., Journal of Pediatric Orthopaedics. Part B, 2021.

Teruhide Koyama, Etsuko Ozaki, Nagato Kuriyama, Satomi Tomida, Tamami Yoshida, Ritei Uehara, Keitaro Tanaka, Megumi Hara, Asahi Hishida, Rieko Okada, Yoko Kubo, Isao Oze, Yuriko Koyanagi, Haruo Mikami, Yohko Nakamura, Ippei Shimoshikiryo, Toshiro Takezaki, Sadao Suzuki, Takahiro Otani, Kiyonori Kuriki, Naoyuki Takashima, Aya Kadota, Kokichi Arisawa, Sakurako Katsuura-Kamano, Hiroaki Ikezaki, Masayuki Murata, Kenji Takeuchi and Kenji Wakai: Effect of Underlying Cardiometabolic Diseases on the Association Between Sedentary Time and All-cause Mortality in a Large Japanese Population: A Cohort Analysis Based on the J-MICC Study, Journal of the American Heart Association, Vol.10, No.13, e018293, 2021.

Imaeda Nahomi, Goto Chiho, Sasakabe Tae, Mikami Haruo, Oze Isao, Hosono Akihiro, Naito Mariko, Miyagawa Naoko, Ozaki Etsuko, Ikezaki Hiroaki, Nanri Hinako, Noriko Tsunematsu-Nakahata, Sakurako Kamano, Kuriki Kiyonori, Tanaka-Yaguchi Yuri, Kayama Takamasa, Kayama Takamasa, Kurihara Ayako, Harada Sei and Wakai Kenji: Reproducibility and validity of food group intake in a short food frequency questionnaire for the middle-aged Japanese population, Environmental Health and Preventive Medicine, Vol.26, No.1, 28, 2021.

Tetsuya Matsuura, Yuki Takata, Toshiyuki Iwame, Jyoji Iwase, Kenji Yokoyama, Shoichiro Takao, Susumu Nishio, Kokichi Arisawa and Koichi Sairyo: Limiting the Pitch Count in Youth Baseball Pitchers Decreases Elbow Pain., Orthopaedic Journal of Sports Medicine, Vol.9, No.3, 2021.

Taro Suzuki, Yasuyuki Nakamura, Yukio Doi, Akira Narita, Atsushi Shimizu, Nahomi Imaeda, Chiho Goto, Kenji Matsui, Aya Kadota, Katsuyuki Miura, Masahiro Nakatochi, Keitaro Tanaka, Megumi Hara, Hiroaki Ikezaki, Masayuki Murata, Toshiro Takezaki, Daisaku Nishimoto, Keitaro Matsuo, Isao Oze, Nagato Kuriyama, Etsuko Ozaki, Haruo Mikami, Yohko Nakamura, Miki Watanabe, Sadao Suzuki, Sakurako Katsuura-Kamano, Kokichi Arisawa, Kiyonori Kuriki, Yukihide Momozawa, Michiaki Kubo, Kenji Takeuchi, Yoshikuni Kita and Kenji Wakai: A Genome-wide Association Study on Confection Consumption in a Japanese Population- The Japan Multi-Institutional Collaborative Cohort study, British Journal of Nutrition, 2021. (DOI: 10.1017/S0007114521000684 )

Fujii Ryosuke, Hishida Asahi, Nishiyama Takeshi, Nakatochi Masahiro, Matsuo Keitaro, Ito Hidemi, Nishida Yuichiro, Shimanoe Chisato, Nakamura Yasuyuki, Turin Chowdhury Tanvir, Suzuki Sadao, Watanabe Miki, Ibusuki Rie, Takezaki Toshiro, Mikami Haruo, Nakamura Yohko, Ikezaki Hiroaki, Murata Masayuki, Kuriki Kiyonori, Kuriyama Nagato, Matsui Daisuke, Kokichi Arisawa, Sakurako Katsuura-Kamano, Tsukamoto Mineko, Tamura Takashi, Kubo Yoko, Kondo Takaaki, Momozawa Yukihide, Kubo Michiaki, Takeuch Kenji, Wakai Kenji and J-MICC Study Group: Assessing the relationship between high-sensitivity C-reactive protein and kidney function employing mendelian randomization in a Japanese community based J-MICC Study, Journal of Epidemiology, 2021. (DOI: 10.2188/jea.JE20200540 , PubMed: 33612706 )

Shiori Suzuki, Atsushi Goto, Masahiro Nakatochi, Akira Narita, Taiki Yamaji, Norie Sawada, Ryoko Katagiri, Masao Iwagami, Akiko Hanyuda, Tsuyoshi Hachiya, Yoichi Sutoh, Isao Oze, Yuriko Koyanagi, Yumiko Kasugai, Yukari Taniyama, Hidemi Ito, Hiroaki Ikezaki, Yuichiro Nishida, Takashi Tamura, Haruo Mikami, Toshiro Takezaki, Sadao Suzuki, Etsuko Ozaki, Kiyonori Kuriki, Naoyuki Takashima, Kokichi Arisawa, Kenji Takeuchi, Kozo Tanno, Atsushi Shimizu, Gen Tamiya, Atsushi Hozawa, Kengo Kinoshita, Makoto Kenji Sasaki Wakai, Masayuki Yamamoto, Keitaro Matsuo, Shoichiro Tsugane and Motoki Iwasaki: Body mass index and colorectal cancer risk: a Mendelian randomization study, Cancer Science, Vol.112, No.4, 1579-1588, 2021. (DOI: 10.1111/cas.14824 , PubMed: 33506574 )

Hishida Asahi, Nakatochi Masahiro, Tamura Takashi, Nagayoshi Mako, Okada Rieko, Kubo Yoko, Tsukamoto Mineko, Kadomatsu Yuka, Suzuki Sadao, Nishiyama Takeshi, Kuriyama Nagato, Watanabe Isao, Takezaki Toshiro, Nishimoto Daisaku, Kuriki Kiyonori, Kokichi Arisawa, Sakurako Katsuura-Kamano, Mikami Haruo, Kusakabe Miho, Oze Isao, Koyanagi Yuriko, Nakamura Yasuyuki, Kadota Aya, Shimanoe Chisato, Tanaka Keitaro, Ikezaki Hiroaki, Murata Masayuki, Kubo Michiaki, Momozawa Yukihide, Takeuchi Kenji and Wakai Kenji: Genome-wide association study of serum PSA levels based on 1000Genomes-imputed data in Japanese: the J-MICC Study, Nagoya Journal of Medical Science, Vol.83, No.1, 183-193, 2021.

予防医学分野業績2020

（論文発表）

H Suzuki, Y Nakamura, K Matsuo, N Imaeda, C Goto, A Narita, A Shimizu, N Takashima, K Matsui, K Miura, M Nakatochi, A Hishida, T Tamura, Y Kadomatsu, R Okada, Y Nishida, C Shimanoe, D Nishimoto, T Takezaki, I Oze, H Ito, H Ikezaki, M Murata, D Matsui, E Ozaki, H Mikami, Y Nakamura, S Suzuki, M Watanabe, Kokichi Arisawa, H Uemura, K Kuriki, Y Momozawa, M Kubo, Y Kita, K Takeuchi and K Wakai: A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern, European Journal of Clinical Nutrition, 2020.

Takashi Tamura, Nagato Kuriyama, Teruhide Koyama, Etsuko Ozaki, Daisuke Matsui, Yuka Kadomatsu, Mineko Tsukamoto, Yoko Kubo, Rieko Okada, Asahi Hishida, Tae Sasakabe, Sayo Kawai, Mariko Naito, Naoyuki Takashima, Aya Kadota, Keitaro Tanaka, Megumi Hara, Sadao Suzuki, Hiroko Nakagawa-Senda, Toshiro Takezaki, Ippei Shimoshikiryo, Hiroaki Ikezaki, Masayuki Murata, Isao Oze, Hidemi Ito, Haruo Mikami, Yohko Nakamura, Kiyonori Kuriki, Kokichi Arisawa, Hirokazu Uemura, Kenji Takeuchi and Kenji Wakai: Association between plasma levels of homocysteine, folate, and vitamin B12, and dietary folate intake and hypertension in a cross-sectional study, Scientific Reports, Vol.10, No.1, 18499, 2020.

Koyama Satoshi, Ito Kaoru, Terao Chikashi, Akiyama Masato, Horikoshi Momoko, Momozawa Yukihide, Matsunaga Hiroshi, Ieki Hirotaka, Ozaki Kouichi, Onouchi Yoshihiro, Takahashi Atsushi, Nomura Seitaro, Morita Hiroyuki, Akazawa Hiroshi, Kim Changhoon, Seo Jeong-sun, Higasa Koichiro, Iwasaki Motoki, Yamaji Taiki, Sawada Norie, Tsugane Shoichiro, Koyama Teruhide, Ikezaki Hiroaki, Takashima Naoyuki, Tanaka Keitaro, Kokichi Arisawa, Kuriki Kiyonori, Naito Mariko, Wakai Kenji, Suna Shinichiro, Sakata Yasuhiko, Sato Hiroshi, Hori Masatsugu, Sakata Yasushi, Matsuda Koichi, Murakami Yoshinori, Aburatani Hiroyuki, Kubo Michiaki, Matsuda Fumihiko, Kamatani Yoichiro and Komuro Issei: Population-specific and transethnic genome-wide analyses reveal distinct and shared genetic risks of coronary artery disease, Nature Genetics, 2020.

I Shimoshikiryo, R Ibusuki, K Shimatani, D Nishimoto, T Takezaki, Y Nishida, C Shimanoe, A Hishida, T Tamura, R Okada, Y Kubo, E Ozaki, D Matsui, S Suzuki, H Nakagawa-Senda, K Kuriki, Y Kita, N Takashima, Kokichi Arisawa, H Uemura, H Ikezaki, N Furusyo, I Oze, YN Koyanagi, H Mikami, Y Nakamura, M Naito and K Wakai : Association between alcohol intake pattern and metabolic syndrome components and simulated change by alcohol intake reduction: A cross-sectional study from the Japan Multi-Institutional Collaborative Cohort Study, Alcohol, Vol.S0741-8329, No.20, 30284-6, 2020.

Kenji Takeuchi, Mariko Naito, Sayo Kawai, Mineko Tsukamoto, Yuka Kadomatsu, Yoko Kubo, Rieko Okada, Mako Nagayoshi, Takashi Tamura, Asahi Hishida, Masahiro Nakatochi, Tae Sasakabe, Shuji Hashimoto, Hidetaka Eguchi, Yukihide Momozawa, Hiroaki Ikezaki, Masayuki Murata, Norihiro Furusyo, Keitaro Tanaka, Megumi Hara, Yuichiro Nishida, Keitaro Matsuo, Hidemi Ito, Isao Oze, Haruo Mikami, Yohko Nakamura, Miho Kusakabe, Toshiro Takezaki, Rie Ibusuki, Ippei Shimoshikiryo, Sadao Suzuki, Takeshi Nishiyama, Miki Watanabe, Teruhide Koyama, Etsuko Ozaki, Isao Watanabe, Kiyonori Kuriki, Yoshikuni Kita, Hirotsugu Ueshima, Kenji Matsui, Kokichi Arisawa, Hirokazu Uemura, Sakurako Katsuura-Kamano, Sho Nakamura, Hiroto Narimatsu, Nobuyuki Hamajima, Hideo Tanaka and Kenji Wakai: Study profile of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study, Journal of Epidemiology, 2020.

Taro Suzuki, Yasuyuki Nakamura, Keitaro Matsuo, Isao Oze, Yukio Doi, Akira Narita, Atsushi Shimizu, Nahomi Imaeda, Chiho Goto, Kenji Matsui, Masahiro Nakatochi, Katsuyuki Miura, Naoyuki Takashima, Kiyonori Kuriki, Chisato Shimanoe, Keitaro Tanaka, Hiroaki Ikezaki, Masayuki Murata, Rie Ibusuki, Toshiro Takezaki, Yuriko Koyanagi, Hidemi Ito, Daisuke Matsui, Teruhide Koyama, Haruo Mikami, Yohko Nakamura, Sadao Suzuki, Takeshi Nishiyama, Sakurako Katsuura-Kamano, Kokichi Arisawa, Kenji Takeuchi, Takashi Tamura, Rieko Okada, Yoko Kubo, Yukihide Momozawa, Michiaki Kubo, Yoshikuni Kita and Kenji Wakai :A genome-wide association study on fish consumption in a Japanese population-the Japan Multi-Institutional Collaborative Cohort study, European Journal of Clinical Nutrition, 2020.

Kokichi Arisawa, Sakurako Katsuura-Kamano, Hirokazu Uemura, Nguyen Van Tien, Asahi Hishida, Takashi Tamura, Yoko Kubo, Mineko Tsukamoto, Keitaro Tanaka, Megumi Hara, Toshiro Takezaki, Daisaku Nishimoto, Teruhide Koyama, Etsuko Ozaki, Sadao Suzuki, Takeshi Nishiyama, Kiyonori Kuriki, Aya Kadota, Naoyuki Takashima, Hiroaki Ikezaki, Masayuki Murata, Isao Oze, Keitaro Matsuo, Haruo Mikami, Yohko Nakamura, Kenji Takeuchi and Kenji Wakai: Association of dietary acid load with the prevalence of metabolic syndrome among participants in the baseline survey of the Japan Multi-Institutional Collaborative Cohort Study, Nutrients, Vol.12, No.6, 1605, 2020. (DOI: 10.3390/nu12061605 , PubMed: 32486113 )

Akiyoshi Nakayama, Masahiro Nakatochi, Yusuke Kawamura, Ken Yamamoto, Hirohumi Nakaoka, Seiko Shimizu, Toshihide Higashino, Teruhide Koyama, Asahi Hishida, Kiyonori Kuriki, Miki Watanabe, Toru Shimizu, Keiko Ooyama, Hiroshi Ooyama, Mitsuo Nagase, Yuji Hidaka, Daisuke Matsui, Takashi Tamura, Takehi Nishiyama, Chisato Shimanoe, Sakurako Katsuura-Kamano, Naoyuki Takashima, Yuya Shirai, Makoto Kawaguchi, Mikiya Takao, Ryo Sugiyama, Yuzo Takada, Takahiro Nakamura, Hiroshi Nakashima, Masashi Tsunoda, Atsushi Hozawa, Kazuyoshi Hosomichi, Yu Toyoda, Yu Kubota, Tappei Takada, Hiroshi Suzuki, Blanka Stiburkova, Tanya Major, Tony Merriman, Nagato Kuriyama, Haruo Mikami, Toshiro Takezaki, Keitaro Matsuo, Sadao Suzuki, Tatsuo Hosoya, Yoichiro Kamatani, Michiaki Kubo, Kimiyoshi Ichida, Kenji Wakai, Itsuro Inoue, Yukinori Okada, Nariyoshi Shinomiya and Hirotaka Matsuo: Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients, Annals of the Rheumatic Diseases, Vol.79, No.5, 657-665, 2020. (DOI: 10.1136/annrheumdis-2019-216644 , PubMed: 32238385 )

Madoka Iwase, Keitaro Matsuo, Masahiro Nakatochi, Isao Oze, Hidemi Ito, Yuriko Koyanagi, Tomotaka Ugai, Yumiko Kasugai, Asahi Hishida, Kenji Takeuchi, Rieko Okada, Yoko Kubo, Chisato Shimanoe, Keitaro Tanaka, Hiroaki Ikezaki, Masayuki Murata, Toshiro Takezaki, Daisaku Nishimoto, Nagato Kuriyama, Etsuko Ozaki, Sadao Suzuki, Miki Watanabe, Haruo Mikami, Yohko Nakamura, Hirokazu Uemura, Sakurako Katsuura-Kamano, Kiyonori Kuriki, Yoshikuni Kita, Takashima Naoyuki, Masato Nagino, Yukihide Momozawa, Michiaki Kubo and Kenji Wakai: Differential effect of polymorphisms on body mass index across the life course of Japanese: the Japan Multi-Institutional Collaborative Cohort Study, Journal of Epidemiology, 2020.

Teruhide Koyama, Nagato Kuriyama, Etsuko Ozaki, Satomi Tomida, Ritei Uehara, Yuichiro Nishida, Chisato Shimanoe, Asahi Hishida, Takashi Tamura, Mineko Tsukamoto, Yuka Kadomatsu, Isao Oze, Keitaro Matsuo, Haruo Mikami, Yohko Nakamura, Rie Ibusuki, Toshiro Takezaki, Sadao Suzuki, Takeshi Nishiyama, Kiyonori Kuriki, Naoyuki Takashima, Aya Kadota, Hirokazu Uemura, Sakurako Katsuura-Kamano, Hiroaki Ikezaki, Masayuki Murata, Kenji Takeuchi and Kenji Wakai: Sedentary time is associated with cardiometabolic diseases in a large Japanese population: a cross-sectional study, Journal of Atherosclerosis and Thrombosis, 2020. (DOI: 10.5551/jat.54320 , PubMed: 32269208 )

Rieko Okada, Yuka Kadomatsu, Mineko Tsukamoto, Tae Sasakabe, Sayo Kawai, Takashi Tamura, Asahi Hishida, Hiroaki Ikezaki, Norihiro Furusyo, Keitaro Tanaka, Megumi Hara, Sadao Suzuki, Miki Watanabe, Toshiro Takezaki, Daisaku Nishimoto, Daisuke Matsui, Isao Watanabe, Kiyonori Kuriki, Naoyuki Takashima, Yasuyuki Nakamura, Sakurako Katsuura-Kamano, Kokichi Arisawa, Haruo Mikami, Yoko Nakamura, Isao Oze, Yuriko N. Koyanagi, Mariko Naito, Kenji Wakai and Japan Multi-Institutional Collaborative Cohort (J-MICC) Study: Combined effect of weight gain within normal weight range and parental hypertension on the prevalence of hypertension; from the J-MICC Study., Journal of Human Hypertension, Vol.34, No.2, 125-131, 2020. (DOI: 10.1038/s41371-019-0230-y , PubMed: 31481698 , Elsevier: Scopus )

K Sakai, C Tanikawa, A Hirasawa, T Chiyoda, W Yamagami, F Kataoka, N Susumu, C Terao, Y Kamatani, A Takahashi, Y Momozawa, M Hirata, M Kubo, N Fuse, T Takai-Igarashi, A Shimizu, A Fukushima, A Kadota, Kokichi Arisawa, H Ikezaki, K Wakai, T Yamaji, N Sawada, M Iwasaki, S Tsugane, D Aoki and K Matsuda: Identification of a novel uterine leiomyoma GWAS locus in a Japanese population., Scientific Reports, Vol.10, No.1, 1197, 2020. (DOI: 10.1038/s41598-020-58066-8 , PubMed: 31988393 )

Tetsuya Matsuura, E Chosa, T Tajika, T Masatomi, S Arimitsu, A Yamamoto, M Nagasawa, Kokichi Arisawa and K Takagishi: Correlation between playing position, elbow physical findings and elbow pain in elementary school baseball players: Results of a multi-regional study in Japan., Journal of Orthopaedic Science, Vol.25, No.1, 122-126, 2020. (DOI: 10.1016/j.jos.2019.02.020 , PubMed: 30922534 )

Kazuyoshi Ishigaki, Masato Akiyama, Masahiro Kanai, Atsushi Takahashi, Eiryo Kawakami, Hiroki Sugishita, Saori Sakaue, Nana Matoba, Siew-Kee Low, Yukinori Okada, Chikashi Terao, Tiffany Amariuta, Steven Gazal, Yuta Kochi, Momoko Horikoshi, Ken Suzuki, Kaoru Ito, Satoshi Koyama, Kouichi Ozaki, Shumpei Niida, Yasushi Sakata, Yasuhiko Sakata, Takashi Kohno, Kouya Shiraishi, Yukihide Momozawa, Makoto Hirata, Koichi Matsuda, Masashi Ikeda, Nakao Iwata, Shiro Ikegawa, Ikuyo Kou, Toshihiro Tanaka, Hidewaki Nakagawa, Akari Suzuki, Tomomitsu Hirota, Mayumi Tamari, Kazuaki Chayama, Daiki Miki, Masaki Mori, Satoshi Nagayama, Yataro Daigo, Yoshio Miki, Toyomasa Katagiri, Osamu Ogawa, Wataru Obara, Hidemi Ito, Teruhiko Yoshida, Issei Imoto, Takashi Takahashi, Chizu Tanikawa, Takao Suzuki, Nobuaki Sinozaki, Shiro Minami, Hiroki Yamaguchi, Satoshi Asai, Yasuo Takahashi, Ken Yamaji, Kazuhisa Takahashi, Tomoaki Fujioka, Ryo Takata, Hideki Yanai, Akihide Masumoto, Yukihiro Koretsune, Hiromu Kutsumi, Masahiko Higashiyama, Shigeo Murayama, Naoko Minegishi, Kichiya Suzuki, Kozo Tanno, Atsushi Shimizu, Taiki Yamaji, Motoki Iwasaki, Norie Sawada, Hirokazu Uemura, Keitaro Tanaka, Mariko Naito, Makoto Sasaki, Kenji Wakai, Shoichiro Tsugane, Masayuki Yamamoto, Kazuhiko Yamamoto, Yoshinori Murakami, Yusuke Nakamura, Soumya Raychaudhuri, Johji Inazawa, Toshimasa Yamauchi, Takashi Kadowaki, Michiaki Kubo, Yoichiro Kamatani. Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nature Genetics 52(7), 669-679, 2020.

Toshiyuki Iwame, Tetsuya Matsuura, Tetsuya Okahisa, Joji Iwase, Hirokazu Uemura, Koichi Sairyo. Factors correlating with recovery of quadriceps strength after double-bundle anterior cruciate ligament reconstruction with hamstring tendon autografts. European Journal of Orthopaedic Surgery & Traumatology: Orthopedie Traumatologie 30(2), 307-312, 2020.

Yuichiro Nishida, Tsuyoshi Hachiya, Megumi Hara, Chisato Shimanoe, Keitaro Tanaka, Yoichi Sutoh, Atsushi Shimizu, Asahi Hishida, Mineko Tsukamoto, Yuka Kadomatsu, Isao Oze, Yuriko N. Koyanagi, Nagato Kuriyama, Teruhide Koyama, Rie Ibusuki, Toshiro Takezaki, Hiroaki Ikezaki, Norihiro Furusyo, Naoyuki Takashima, Aya Kadota, Hirokazu Uemura, Sakurako Katsuura-Kamano, Sadao Suzuki, Hiroko Nakagawa-Senda, Kiyonori Kuriki, Haruo Mikami, Yohko Nakamura, Yukihide Momozawa, Michiaki Kubo, Masahiro Nakatochi, Mariko Naito, Kenji Wakai. The interaction between ABCA1 polymorphism and physical activity on the HDL-cholesterol levels in a Japanese population. Journal of Lipid Research 61, 86-94, 2020.(DOI:10.1194/jlr.P091546, PubMed: 31694877)

予防医学分野業績2019

（英文論文）

Y Usui, K Matsuo, I Oze, T Ugai, Y Koyanagi, Y Maeda, H Ito, A Hishida, K Takeuchi, T Tamura, M Tsukamoto, Y Kadomatsu, M Hara, Y Nishida, I Shimoshikiryo, T Takezaki, E Ozaki, D Matsui, I Watanabe, S Suzuki, M Watanabe, H Nakagawa-Senda, H Mikami, Y Nakamura, Kokichi Arisawa, Hirokazu Uemura, K Kuriki, N Takashima, A Kadota, H Ikezaki, M Murata, M Nakatochi, Y Momozawa, M Kubo and K Wakai: Impact of PSCA polymorphisms on the risk of duodenal ulcer.,
Journal of Epidemiology, JE20190184, 2019. (DOI:10.2188/jea.JE20190184, PubMed: 31839644)

Yusuke Kawamura, Hirofumi Nakaoka, Akiyoshi Nakayama, Yukinori Okada, Ken Yamamoto, Toshihide Higashino, Masayuki Sakiyama, Toru Shimizu, Hiroshi Ooyama, Keiko Ooyama, Mitsuo Nagase, Yuji Hidaka, Yuko Shirahama, Kazuyoshi Hosomichi, Yuichiro Nishida, Ippei Shimoshikiryo, Asahi Hishida, Sakurako Katsuura-Kamano, Seiko Shimizu, Makoto Kawaguchi, Hirokazu Uemura, Rie Ibusuki, Megumi Hara, Mariko Naito, Mikiya Takao, Mayuko Nakajima, Satoko Iwasawa, Hiroshi Nakashima, Keizo Ohnaka, Takahiro Nakamura, Blanka Stiburkova, Tony R. Merriman, Masahiro Nakatochi, Sahoko Ichihara, Mitsuhiro Yokota, Tappei Takada, Tatsuya Saitoh, Yoichiro Kamatani, Atsushi Takahashi, Kokichi Arisawa, Toshiro Takezaki, Keitaro Tanaka, Kenji Wakai, Michiaki Kubo, Tatsuo Hosoya, Kimiyoshi Ichida, Ituro Inoue, Nariyoshi Shinomiya and Hirotaka Matsuo: Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout., Annals of the Rheumatic Diseases, Vol.78, No.10, 1430-1437, 2019. (DOI: 10.1136/annrheumdis-2019-215521, PubMed: 31289104)

R Fujii, A Hishida, M Nakatochi, N Furusyo, M Murata, K Tanaka, C Shimanoe, S Suzuki, M Watanabe, N Kuriyama, T Koyama, T Takezaki, I Shimoshikiryo, Kokichi Arisawa, Sakurako Katsuura-Kamano, N Takashima, TC Turin, K Kuriki, K Endoh, H Mikami, Y Nakamura, I Oze, H Ito, M Kubo, Y Momozawa, T Kondo, M Naito and K Wakai: Association of genetic risk score and chronic kidney disease in a Japanese population, Nephrology, Vol.24, No.6, 670-673, 2019. (DOI: 10.1111/nep.13479, PubMed: 30146708)

Makoto Irahara, Wakako Shinahara, Mayumi Sugimoto, Yukiko Ogawa, Keiji Shitsukawa, Kenji Kubota, Limin Yang, Yukihiro Ohya, Hirohisa Saito, Shoji Kagami, Kokichi Arisawa and Hiroshi Kido: Trajectories of class-switching-related egg and cow's milk allergen-specific immunoglobulin isotype formation and its modification by eczema with low- and high-affinity immunoglobulin E during early infancy, Immunity, Inflammation and Disease, Vol.7, No.2, 74-85, 2019. (DOI: 10.1002/iid3.245, PubMed: 30859748, Elsevier: Scopus)

Yuki Iwasaki, Kokichi Arisawa, Sakurako Katsuura-Kamano, Hirokazu Uemura, Mineko Tsukamoto, Yuka Kadomatsu, Rieko Okada, Asahi Hishida, Keitaro Tanaka, Megumi Hara, Toshiro Takezaki, Keiichi Shimatani, Etsuko Ozaki, Teruhide Koyama, Sadao Suzuki, Hiroko Nakagawa-Senda, Kiyonori Kuriki, Naoko Miyagawa, Aya Kadota, Hiroaki Ikezaki, Norihiro Furusyo, Isao Oze, Hidemi Ito, Haruo Mikami, Yohko Nakamura and Kenji Wakai: Associations of nutrient patterns with the prevalence of metabolic syndrome: Results from the baseline data of the Japan Multi-Institutional Collaborative Cohort Study, Nutrients, Vol.11, No.5, 990, 2019. (DOI: 10.3390/nu11050990, PubMed: 31052301, Elsevier: Scopus)

Hirokazu Uemura, Sakurako Katsuura-Kamano, Yuki Iwasaki, Kokichi Arisawa, Asahi Hishida, Rieko Okada, Takashi Tamura, Yoko Kubo, Hidemi Ito, Isao Oze, Chisato Shimanoe, Yuichiro Nishida, Yasuyuki Nakamura, Naoyuki Takashima, Sadao Suzuki, Hiroko Nakagawa-Senda, Daisaku Nishimoto, Toshiro Takezaki, Haruo Mikami, Yohko Nakamura, Norihiro Furusyo, Hiroaki Ikezaki, Etsuko Ozaki, Teruhide Koyama, Kiyonori Kuriki, Kaori Endoh, Mariko Naito and Kenji Wakai: Independent relationships of daily life activity and leisure-time exercise with metabolic syndrome and its traits in the general Japanese population., Endocrine, Vol.64, No.3, 552-563, 2019. doi: 10.1007/s12020-019-01926-9

Masahiro Nakatochi, Masahiro Kanai, Akiyoshi Nakayama, Asahi Hishida, Yusuke Kawamura, Sahoko Ichihara, Masato Akiyama, Hiroaki Ikezaki, Norihiro Furusyo, Seiko Shimizu, Ken Yamamoto, Makoto Hirata, Rieko Okada, Sayo Kawai, Makoto Kawaguchi, Yuichiro Nishida, Chisato Shimanoe, Rie Ibusuki, Toshiro Takezaki, Mayuko Nakajima, Mikiya Takao, Etsuko Ozaki, Daisuke Matsui, Takeshi Nishiyama, Sadao Suzuki, Naoyuki Takashima, Yoshikuni Kita, Kaori Endoh, Kiyonori Kuriki, Hirokazu Uemura, Kokichi Arisawa, Isao Oze, Keitaro Matsuo, Yohko Nakamura, Haruo Mikami, Takashi Tamura, Hiroshi Nakashima, Takahiro Nakamura, Norihiro Kato, Koichi Matsuda, Yoshinori Murakami, Tatsuaki Matsubara, Mariko Naito, Michiaki Kubo, Yoichiro Kamatani, Nariyoshi Shinomiya, Mitsuhiro Yokota, Kenji Wakai, Yukinori Okada and Hirotaka Matsuo: Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals., Communications Biology, Vol.2, 115, 2019. doi: 10.1038/s42003-019-0339-0. eCollection 2019.

Takeshi Nishiyama, Masahiro Nakatochi, Atsushi Goto, Motoki Iwasaki, Tsuyoshi Hachiya, Yoichi Sutoh, Atsushi Shimizu, Chaochen Wang, Hideo Tanaka, Miki Watanabe, Akihiro Hosono, Yuya Tamai, Tamaki Yamada, Taiki Yamaji, Norie Sawada, Kentaro Fukumoto, Kotaro Otsuka, Kozo Tanno, Hiroaki Tomita, Kaname Kojima, Masao Nagasaki, Atsushi Hozawa, Asahi Hishida, Tae Sasakabe, Yuichiro Nishida, Megumi Hara, Hidemi Ito, Isao Oze, Yohko Nakamura, Haruo Mikami, Rie Ibusuki, Toshiro Takezaki, Teruhide Koyama, Nagato Kuriyama, Kaori Endoh, Kiyonori Kuriki, C Tanvir Turin, Takashima Naoyuki, Sakurako Katsuura-Kamano, Hirokazu Uemura, Rieko Okada, Sayo Kawai, Mariko Naito, Yukihide Momozawa, Michiaki Kubo, Makoto Sasaki, Masayuki Yamamoto, Shoichiro Tsugane, Kenji Wakai and Sadao Suzuki: Genome-wide association meta-analysis and Mendelian randomization analysis confirm ALDH2 influencing on sleep duration in the Japanese population., Sleep, 2019. Feb 22. pii: zsz046. doi: 10.1093/sleep/zsz046. [Epub ahead of print]

Basilua Andre Muzembo, Miyuki Iwai-shimada, Tomohiko Isobe, Kokichi Arisawa, Masayuki Shima, Tetsuhito Fukushima and Shoji F. Nakayama: Dioxins levels in human blood after implementation of measures against dioxin exposure in Japan, Environmental Health and Preventive Medicine, Vol.24, No.1, 6, 2019. (DOI: 10.1186/s12199-018-0755-7, PubMed: 30630405)

Tetsuya Matsuura, Toshiyuki Iwame, Naoto Suzue, Shoichiro Takao, Susumu Nishio, Kokichi Arisawa and Koichi Sairyo: Cumulative Incidence of Osteochondritis Dissecans of the Capitellum in Preadolescent Baseball Players., Arthroscopy: the Journal of Arthroscopic & Related Surgery, Vol.35, No.1, 60-66, 2019. (DOI: 10.1016/j.arthro.2018.08.034, PubMed: 30611367, Elsevier: Scopus)

Yumi Kuwamura, Eijiro Sakamoto, Masuko Sumikawa, Munehide Matsuhisa, Daisuke Hinode, Hirokazu Uemura, Sachi Kishida. Assessing the oral health of in-patients with diabetes using a clinical version of the Diabetes Oral Health Assessment Tool© and its association with dental examinations. The Journal of Medical Investigation: JMI 66(3.4), 328-336, 2019.

Toshiyuki Iwame, Tetsuya Matsuura, Naoto Suzue, Joji Iwase, Hirokazu Uemura, Koichi Sairyo. Factors Associated with Knee Pain and Heel Pain in Youth Soccer Players Aged 8 to 12 Years. Orthopaedic Journal of Sports Medicine 7(11), 2325967119883370, 2019.

Matsuzaki K, Yasui T, Matsui S, Fukuoka M, Uemura H. Differences in menopausal symptoms and coping strategies according to personality in Japanese nurses. J Obstet Gynaecol. 2019 Feb;39(2):242-247. doi: 10.1080/01443615.2018.1498468.

上村浩一, 釜野桜子, NGUYEN TIEN VAN, 有澤孝吉 :労働者における脂肪肝の簡易指標である Fatty Liver Index と慢性炎症や動脈スティフネスとの関連: J-MICC Study 徳島地区調査より,第63回中国四国合同産業衛生学会, 2019年12月.

上村浩一, 釜野桜子, 有澤孝吉 :日常の生活活動および余暇時の運動とメタボリック症候群との関連:J-MICC Study,第78回日本公衆衛生学会総会, 2019年10月.

釜野桜子, 上村浩一, 有澤孝吉 :朝食欠食および睡眠時間とメタボリック症候群との関連:J-MICC Study,第78回日本公衆衛生学会総会, 2019年10月.

岩崎夕貴, 釜野桜子, 上村浩一, 有澤孝吉 :栄養素パターンとメタボリックシンドロームとの関連の検討,第64回四国公衆衛生学会, 2019年2月.

上村浩一, 釜野桜子, 岩﨑夕貴, 有澤孝吉 :日常の身体活動および余暇時の運動とメタボリック症候群やその構成因子との関連の検討,第89回日本衛生学会学術総会, 2019年2月.

上村浩一, 釜野桜子, 岩﨑夕貴, 有澤孝吉 :脂肪肝の簡易指標であるFatty liver indexと慢性炎症や動脈スティフネスとの関連,第29回日本疫学会学術総会, 2019年2月.

予防医学分野業績2018

（英文論文）

Uemura H, Katsuura-Kamano S, Nakamoto M, Yamaguchi M, Fujioka M, Iwasaki Y, Arisawa K. Inverse association between soy food consumption, especially fermented soy products intake and soy isoflavone, and arterial stiffness in Japanese men. Sci Rep. 2018 Jun 25;8(1):9667. doi: 10.1038/s41598-018-28038-0.

Hishida A, Nakatochi M, Akiyama M, Kamatani Y, Nishiyama T, Ito H, Oze I, Nishida Y, Hara M, Takashima N, Turin TC, Watanabe M, Suzuki S, Ibusuki R, Shimoshikiryo I, Nakamura Y, Mikami H, Ikezaki H, Furusyo N, Kuriki K, Endoh K, Koyama T, Matsui D, Uemura H, Arisawa K, Sasakabe T, Okada R, Kawai S, Naito M, Momozawa Y, Kubo M, Wakai K; Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group. Genome-Wide Association Study of Renal Function Traits: Results from the Japan Multi-Institutional Collaborative Cohort Study. Am J Nephrol. 2018;47(5):304-316. doi: 10.1159/000488946.

Shimanoe C, Hachiya T, Hara M, Nishida Y, Tanaka K, Sutoh Y, Shimizu A, Hishida A, Kawai S, Okada R, Tamura T, Matsuo K, Ito H, Ozaki E, Matsui D, Ibusuki R, Shimoshikiryo I, Takashima N, Kadota A, Arisawa K, Uemura H, Suzuki S, Watanabe M, Kuriki K, Endoh K, Mikami H, Nakamura Y, Momozawa Y, Kubo M, Nakatochi M, Naito M, Wakai K. A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. Genes Brain Behav. 2018 Apr 17:e12481. doi: 10.1111/gbb.12481. [Epub ahead of print]

Yang X, Nakamoto M, Shuto E, Hata A, Aki N, Shikama Y, Bando Y, Ichihara T, Minamigawa T, Kuwamura Y, Tamura A, Uemura H, Arisawa K, Funaki M, Sakai T. Associations between intake of dietary fermented soy food and concentrations of inflammatory markers: a cross-sectional study in Japanese workers. J Med Invest. 2018;65(1.2):74-80. doi: 10.2152/jmi.65.74.

Bahari T, Uemura H, Katsuura-Kamano S, Yamaguchi M, Nakamoto M, Miki K, Ishizu M, Arisawa K. Nutrient-Derived Dietary Patterns and Their Association With Metabolic Syndrome in a Japanese Population. J Epidemiol. 2018 Apr 5;28(4):194-201. doi: 10.2188/jea.JE20170010.

Nakagawa-Senda H, Hachiya T, Shimizu A, Hosono S, Oze I, Watanabe M, Matsuo K, Ito H, Hara M, Nishida Y, Endoh K, Kuriki K, Katsuura-Kamano S, Arisawa K, Nindita Y, Ibusuki R, Suzuki S, Hosono A, Mikami H, Nakamura Y, Takashima N, Nakamura Y, Kuriyama N, Ozaki E, Furusyo N, Ikezaki H, Nakatochi M, Sasakabe T, Kawai S, Okada R, Hishida A, Naito M, Wakai K, Momozawa Y, Kubo M, Tanaka H. A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study. Sci Rep. 2018 Jan 24;8(1):1493.

Katsuura-Kamano S, Uemura H, Yamaguchi M, Nakamoto M, Bahari T, Miki K, Ishizu M, Sawachika F, Arisawa K. Dietary calcium intake is associated with serum high-sensitivity C-reactive protein level in the general Japanese population. J Clin Biochem Nutr Jan 2018; 62(1): 89-93.

（国内学会一般演題）

上村浩一、釜野桜子、岩崎夕貴、有澤孝吉．日常の身体活動および余暇時の運動とメタボリック症候群やその構成因子との関連の検討．第89回日本衛生学会学術総会．2019.2.1～2.3、名古屋大学東山キャンパス（愛知県名古屋市）

上村浩一、釜野桜子、岩崎夕貴、有澤孝吉．脂肪肝の簡易指標であるFatty liver indexと慢性炎症や動脈スティフネスとの関連．第29回日本疫学会学術総会．2019.1.30～2.1、一橋大学一橋講堂（東京都千代田区）

松井寿美佳、安井敏之、上村浩一、苛原稔．周閉経期におけるコルチゾールの変化と脂質代謝との関連．第33回日本女性医学学会学術集会．2018年11月3日～4日、岐阜県岐阜市

松崎和代、安井敏之、松井寿美佳、上村浩一．看護師の喫煙者及び非喫煙者における更年期症状並びに対処行動の違い．第33回日本女性医学学会学術集会．2018年11月3日～4日、岐阜県岐阜市

松井寿美佳、安井敏之、上村浩一、苛原稔．周閉経期のFSHのばらつきとBMIとの関連．第33回日本女性医学学会学術集会．2018年11月3日～4日、岐阜県岐阜市

石原留美、永峰啓子、上村浩一、安井敏之．エストロゲンの変化に伴う産褥期のほてりや寝汗並びにその関連要因の検討．第33回日本女性医学学会学術集会．2018年11月3日～4日、岐阜県岐阜市

上村浩一、釜野桜子、有澤孝吉．Hepatic steatosis indexやFatty liver indexと慢性炎症や動脈スティフネスとの関連．第77回日本公衆衛生学会総会．2018年10月24日～10月26日、福島県郡山市

松井寿美佳、安井敏之、上村浩一、苛原稔．副腎アンドロゲンはホルモン補充療法中、わずかなエストロゲンの増加でも低下する．第70回日本産科婦人科学会学術講演会．2018年5月10日～13日、宮城県仙台市．

松井寿美佳、安井敏之、上村浩一、苛原稔．周閉経期女性におけるコルチゾールの変化と脂質代謝との関連．第91回日本内分泌学会学術総会．2018年4月26日～28日、宮崎県宮崎市

上村浩一、釜野桜子、藤岡美穂、岩崎夕貴、有澤孝吉．日本人男性における大豆食品や大豆イソフラボンの摂取状況と動脈スティフネスとの関連．第88回日本衛生学会学術総会．2018.3.22～3.24 東京工科大学蒲田キャンパス（東京都大田区）

上村浩一、釜野桜子、Bahari Tirani、藤岡美穂、岩崎夕貴、有澤孝吉．日本人男性における大豆食品摂取と動脈スティフネスとの関連：J-MICC Study徳島地区調査．第28回日本疫学会学術総会、平成30年2月1日～2月3日、コラッセふくしま（福島県福島市）

嵩下賢、内田雄三、上村浩一、徳永了亮、才木茜、早稲田宗、石居敏文．増悪を繰り返す心不全患者の背景要因の検討．第82回日本循環器学会学術集会．2018.3.23～3.25 大阪市

藤岡美穂、上村浩一、釜野桜子、岩崎夕貴、有澤孝吉．炎症関連遺伝子とメタボリックシンドロームの関連性の検討．第63回四国公衆衛生学会総会・平成29年度四国公衆衛生研究発表会．2018.1.25～1.26、高知県高知市

予防医学分野業績2017

（英文論文）

Yuko Uemura, Toshiyuki Yasui, Kimiyo Horike, Kazuhisa Maeda, Hirokazu Uemura, Mari Haku, Reiko Sakae and Keiko Matsumura. Association of low back and pelvic pain at the second trimester with that at the third trimester and puerperium in Japanese pregnant women. J Preg Child Health 2017, 4:5 DOI: 10.4172/2376-127X.1000351

Takagi S, Naito M, Kawai S, Okada R, Nagata C, Hosono S, Nishida Y, Takashima N, Suzuki S, Shimoshikiryo I, Mikami H, Uemura H, Kuriyama N, Ohnaka K, Kubo M, Hamajima N, Tanaka H, Wakai K. Macronutrient intakes and serum oestrogen, and interaction with polymorphisms in CYP19A1 and HSD17B1 genes: a cross-sectional study in postmenopausal Japanese women.

Br J Nutr. 2017 Sep;118(6):463-472. doi: 10.1017/S0007114517002239.

Koyama T, Kuriyama N, Ozaki E, Matsui D, Watanabe I, Takeshita W, Iwai K, Watanabe Y, Nakatochi M, Shimanoe C, Tanaka K, Oze I, Ito H, Uemura H, Katsuura-Kamano S, Ibusuki R, Shimoshikiryo I, Takashima N, Kadota A, Kawai S, Sasakabe T, Okada R, Hishida A, Naito M, Kuriki K, Endoh K, Furusyo N, Ikezaki H, Suzuki S, Hosono A, Mikami H, Nakamura Y, Kubo M, Wakai K. Genetic Variants of RAMP2 and CLR are Associated with Stroke. J Atheroscler Thromb. 2017 Sep 14. doi: 10.5551/jat.41517. [Epub ahead of print]

Matsui S, Yasui T, Kasai K, Yoshida K, Kato T, Uemura H, Kuwahara A, Matsuzaki T, Irahara M. Circulating dehydroepiandrosterone-sulphate decreases even with a slight change in oestradiol.

J Obstet Gynaecol. 2017:14:1-5. doi: 10.1080/01443615.2017.1344829.

Bahari T, Uemura H, Katsuura-Kamano S, Yamaguchi M, Nakamoto M, Miki K, Sawachika F, Arisawa K. Association between dietary patterns and serum adiponectin: a cross-sectional study in a Japanese population. Int J Food Sci Nutr. 2017:21:1-10. doi: 10.1080/09637486.2017.1338249.

Hirokazu Uemura, Sakurako Katsuura-Kamano, Miwa Yamaguchi, Tirani Bahari, Masashi Ishizu, Miho Fujioka, Kokichi Arisawa.

Relationships of serum high-sensitivity C-reactive protein and body size with insulin resistance in a Japanese cohort.PLoS One. 2017 Jun 2;12(6):e0178672. doi: 10.1371/journal.pone.0178672. eCollection 2017.

Hirokazu Uemura, A. Ammar Ghaibeh, Sakurako Katsuura-Kamano, Miwa Yamaguchi, Tirani Bahari, Masashi Ishizu, Hiroki Moriguchi, Kokichi Arisawa. Systemic inflammation and family history in relation to the prevalence of type 2 diabetes based on an alternating decision tree. Scientific Reports,2017 Mar 31;7:45502. doi: 10.1038/srep45502.

Matsui S, Yasui T, Kasai K, Keyama K, Yoshida K, Kato T, Uemura H, Kuwahara A, Matsuzaki T, Irahara M. Sex hormone-binding globulin and antithrombin III activity in women with oral ultra-low-dose estradiol. J Obstet Gynaecol. 2017 Mar 20:1-6. doi: 10.1080/01443615.2017.1285275.

Kazuyo Matsuzaki, Toshiyuki Yasui, Miwa Fukuoka and Hirokazu Uemura. Differences in Associations of Menopausal Symptoms with Job-related Stress Factors in Full-time and Part-time Workers in Japan. Int J Women’s Health Care. 2017;1(1).

Yuko Uemura, Toshiyuki Yasui, Kimiyo Horike, Kazuhisa Maeda, Hirokazu Uemura, Mari Haku, Reiko Sakae, Keiko Matsumura. Factors related with low back pain and pelvic pain at the early stage of pregnancy in Japanese women. International Journal of Nursing and Midwifery. 2017;9(1):1-9. DOI: 10.5897/IJNM2016.0249

Sasakabe T, Wakai K, Kawai S, Hishida A, Naito M, Suzuki S, Nindita Y, Arisawa K, Kita Y, Hara M, Kuriyama N, Hirata A, Mikami H, Oze I, Kubo M, Tanaka H, Hamajima N. Modification of the Associations of Alcohol Intake With Serum Low-Density Lipoprotein Cholesterol and Triglycerides by ALDH2 and ADH1B Polymorphisms in Japanese Men. J Epidemiol. 2017 Nov 25. doi: 10.2188/jea.JE20160189.

（国際学会一般演題）

Yumi Kuwamura, Sumikawa Masuko, Eijiro Sakamoto, Takikawa Ineko, Yamako Hikari, Hirokazu Uemura, Sachi Kishida, Toshihiko Nagata and Munehide Matsuhisa. Nurses' Implementation and Opinion of Assessment of Oral Health Behavior in Patients with Diabetes.The 9th Scientific Meeting of the Asian Association for the Study of Diabetes.2017.5.19-20 Nagoya

（国内学会一般演題）

松崎和代、福岡美和、安井敏之、上村浩一．タイプA行動パターン及び非タイプA行動パターンによる看護師の更年期症状並びに対処行動の違いの検討．第32回日本女性医学学会学術集会．2017年11月4日～5日、大阪

植村裕子、安井敏之、上村浩一．妊娠期から産褥期における腰痛の縦断的検討．第32回日本女性医学学会学術集会．2017年11月4日～5日、大阪

松井寿美佳, 安井敏之, 笠井可菜，吉田加奈子, 加藤剛志, 上村浩一, 苛原稔．ホルモン補充療法中、デヒドロエピアンドロステロンサルフェートは、わずかなエストロゲンの増加でも低下する．第32回日本女性医学学会学術集会．2017年11月4日～5日、大阪

上村浩一、釜野桜子、有澤孝吉．日本人男性における大豆食品摂取と動脈スティフネスとの関連．第76回日本公衆衛生学会総会．2017年10月31日～11月2日、鹿児島

上村浩一、釜野桜子、山口美輪、Bahari Tirani、石津将、藤岡美穂、有澤孝吉．一般集団における慢性炎症とインスリン代謝関連指標との関係の検討．第87回日本衛生学会学術総会．．2017年3月26日～28日、宮崎

予防医学分野業績2016

（英文論文）

Higashibata T, Wakai K, Naito M, Morita E, Hishida A, Hamajima N, Hara M4, Suzuki S, Hosono S, Takashima N, Ohnaka K, Takada A, Mikami H, Watanabe Y, Uemura H, Kubo M, Tanaka H Effects of self-reported calorie restriction on correlations between SIRT1 polymorphisms and body mass index and long-term weight change.Gene. 2016 Dec 5;594(1):16-22. doi: 10.1016/j.gene.2016.08.051.

Hinako Nanri, Yuichiro Nishida, Kazuyo Nakamura, Keitaro Tanaka, Mariko Naito, Guang Yin, Nobuyuki Hamajima, Naoyuki Takashima, Sadao Suzuki, Yora Nindita, Michiko Kohno, Hirokazu Uemura, Teruhide Kyoyama, Satoyo Hosono, Haruo Mikami, Michiaki Kubo, Hideo Tanaka. Associations between dietary patterns, ADRβ2 Gln27Glu and ADRβ3 Trp64Arg with regard to serum triglyceride levels: J-MICC Study.Nutrients. 2016 Sep 6;8(9). pii: E545. doi: 10.3390/nu8090545.

Yin G, Naito M, Wakai K, Morita E, Kawai S, Hamajima N, Suzuki S, Kita Y, Takezaki T, Tanaka K, Morita M, Uemura H, Ozaki E, Hosono S, Mikami H, Kubo M, Tanaka H; Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group. ALDH2 polymorphism is associated with fasting blood glucose through alcohol consumption in Japanese men. Nagoya J Med Sci. 2016 May;78(2):183-93.

Matsui S, Yasui T, Kasai K, Keyama K, Kato T, Uemura H, Kuwahara A, Matsuzaki T, Irahara M. Changes of liver enzymes and triglyceride during the menopausal transition in Japanese women.J Obstet Gynaecol. 2016 Aug;36(6):806-811.

Matsuzaki K, Uemura H, Yasui T. Differences in coping with menopausal symptoms in nurses and general workers in Japan. Maturitas. 2016 Apr;86:45-52. doi: 10.1016/j.maturitas.2016.01.010.

T Matsuura, N Suzue, T Iwame, Kokichi Arisawa, S Fukut and K Sairyo : Epidemiology of shoulder and elbow pain in youth baseball players, Phys Sportsmed (in press), 2016.

Sawachika F, Uemura H, Katsuura-Kamano S, Yamaguchi M, Bahari T, Miki K, Todo S, Inoo M, Onishi I, Kurata N, Arisawa K. Changes in foot function, disease activity, and disability after forefoot resection arthroplasty in patients with rheumatoid arthritis. J Med Invest. 2016;63(1-2):38-44. doi: 10.2152/jmi.63.38.

Uemura H, Katsuura-Kamano S, Yamaguchi M, Arisawa K, Hamajima N, Hishida A, Kawai S, Oze I, Shinchi K, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Kuriyama N, Kubo M, Tanaka H; Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group. A variant of the CLOCK gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population.J Diabetes. 2015 Sep 16. doi: 10.1111/1753-0407.12344.

Matsui S, Yasui T, Kasai K, Keyama K, Kato T,Uemura H, Kuwahara A, Matsuzaki T, Irahara M. Increase in circulating sclerostin at the early stage of menopausal transition in Japanese women. Maturitas. 2016 Jan;83:72-7.doi: 10.1016/j.maturitas.2015.10.001.

（国内学会シンポジウム）

上村浩一．「エイジングと女性のがん」エイジングと乳がんアンチエイジング療法との関連も含めて．第16回日本抗加齢医学会総会．2016年6月10日～12日、横浜

（国内学会一般演題）

高橋久美、安井敏之、上村浩一．交代制勤務を行う女性の月経周期の規則性と睡眠の質や量、および食生活や生活習慣との関係や特性．第31回日本女性医学学会学術集会．2016.11.5～6、京都．

松崎和代、福岡美和、上村浩一、安井敏之．フルタイムおよびパートタイム女性労働者における更年期症状と仕事におけるストレスとの関連．第31回日本女性医学学会学術集会．2016.11.5～6、京都．

上村浩一、釜野桜子、山口美輪、有澤孝吉．慢性炎症とインスリン抵抗性との関連：体格や生活習慣との交互作用を含めて．第75回日本公衆衛生学会総会．2016年10月26日～28日、大阪

岩佐武、松崎利也、Tungalagsuvd Altankhuu、Munkhzaya Munkhsaikhan、河見貴子、仁木博文、加藤剛志、桑原章、上村浩一、安井敏之、苛原稔．（学会賞受賞講演）ストレスが視床下部におけるKiss1およびRFRP遺伝子発現と生殖機能に及ぼす影響．第69中国四国産科婦人科学会総会ならびに学術講演会． 2016.9.24～25、高松．

上村浩一、釜野桜子、山口美輪、Tirani Bahari、三木啓輔、石津将、有澤孝吉．肥満および慢性炎症とインスリン抵抗性との関連：J-MICC Study徳島地区調査より．第86回日本衛生学会学術総会．2016年5月11日～13日、旭川

松井寿美佳、安井敏之、笠井可菜、毛山薫、吉田加奈子、加藤剛志、上村浩一、苛原稔．超低用量経口エストラジオールは性ホルモン結合グロブリンを増加させる．第68回日本産科婦人科学会学術講演会．2016年4月21日～24日、東京．

三木啓輔、上村浩一、釜野桜子、山口美輪、Tirani Bahari、澤近房和、石津将、有澤孝吉．カリウム・ビタミンB1・ビタミンB2の摂取とインスリン抵抗性との関連についての検討 J-MICC Study徳島地区のデータより．第61回四国公衆衛生学会総会・平成27年度四国公衆衛生研究発表会．2016年2月4～5日、徳島

予防医学分野業績2015

（英文論文）

Yoshitoshi Ogura, Shakhinur Islam Mondal, Md Rakibul Islam, Toshihiro Mako, Kokichi Arisawa, Keisuke Katsura, Tadasuke Ooka, Yasuhiro Gotoh, Kazunori Murase, Makoto Ohnishi and Tetsuya Hayashi : The Shigatosin 2 production level in enterohemorrhagic Escherichia coli O157:H7 is correlated with the subtypes of toxin-encoding phage, Scientific Reports, Vol.5, p.16663, 2015.

Teruhide Koyama, Daisuke Matsui, Nagato Kuriyama, Etsuko Ozaki, Keitaro Tanaka, Isao Oze, Nobuyuki Hamajima, Kenji Wakai, Rieko Okada, Kokichi Arisawa, Haruo Mikami, Keiichi Shimatani, Akie Hirata, Naoyuki Takashima, Sadao Suzuki, Chisato Nagata, Michiaki Kubo and Hideo Tanaka : Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinaemia in Japanese men, Scientific Reports, Vol.5, p.15888, 2015.

Yumi Kuwamura, Masuko Sumikawa, Tetsuya Tanioka, Toshihiko Nagata, Eijiro Sakamoto, Hiromi Murata, Munehide Matsuhisa, Ken-ichi Aihara, Daisuke Hinode, Hirokazu Uemura, Hirokazu Ito, Yuko Yasuhara, Rozzano Locsin. Development of the Diabetes Oral Health Assessment Tool (C) for Nurses. Health. Pub. Date: December 28, 2015.

Miwa Yamaguchi, Hirokazu Uemura, Kokichi Arisawa, Sakurako Katsuura-Kamano, Nobuyuki Hamajima,Asahi Hishida,Shino Suma, Isao Oze, Kazuyo Nakamura, Naoyuki Takashima, Sadao Suzuki, Rie Ibusuki, Haruo Mikami, Keizo Ohnaka,Nagato Kuriyama, Michiaki Kubo, and Hideo Tanakafor the Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group. Association between brain-muscle-ARNT-like protein-2 (BMAL2) gene polymorphism and type 2 diabetes mellitus in obese Japanese individuals: A cross-sectional analysis of the Japan Multi-Institutional Collaborative Cohort Study. Diabetes Research and Clinical Practice.2015 Dec;110(3):301-8.

Y Sugimoto, K Wakai, H Nakagawa, S Suma, T Sasakabe, T Sakamoto, N Takashima, S Suzuki, S Ogawa, K Ohnaka, N Kuriyama, Kokichi Arisawa, H Mikami, M Kubo, S Hosono, N Hamajima, H Tanaka and J-MICC Study Group: Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers: a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study, Gene 2015;557(2):158-162.

Hirokazu Uemura, Sakurako Katsuura-Kamano, Miwa Yamaguchi, Kokichi Arisawa. Relationships of elevated levels of serum hepatic enzymes and alcohol intake with arterial stiffness in men. Atherosclerosis. 2015;238(1):83-8.

Ayako Kino, Toshiyuki Yasui, Hirokazu Uemura. Different Levels of Awareness and Knowledge of Male Climacteric in Female Nurses and Female Office Workers. Maturitas. 2015;80(2):198-204.

Tani A, Yamamoto S, Maegawa M, Kunimi K, Matsui S, Keyama K, Kato T, Uemura H, Kuwahara A, Matsuzaki T, Yasui T, Kamada M, Soeki T, Sata M, Irahara M. Arterial stiffness is increased in young women with endometriosis. J Obstet Gynaecol. (in press)

Tetsuya Enishi, Hirokazu Uemura, Shinsuke Katoh, Masanori Inatsugi, Sho Minato, Kei Inatsugi, Mikiko Inatsugi, Nori Sato and Koichi Sairyo. Transient severe hypotension following a weekly subcutaneous injection of teriparatide in an osteoporotic patient: a case report and insight for drug interaction between hypotensive agents and teriparatide.The Journal of Medical Investigation.2015;62(1,2):93-6.

（国内学会一般演題）

上村浩一、山口美輪、釜野桜子、有澤孝吉、J-MICC Study Group．日本人におけるCLOCK遺伝子多型と肥満、過体重および2型糖尿病との関連：J-MICC Study．第74回日本公衆衛生学会総会．2015年11月4日～6日、長崎

嵩下賢、上村浩一、後藤尚．長崎県五島市における献血者数増加への取り組み．第74回日本公衆衛生学会総会．2015年11月4日～6日、長崎

松崎和代、安井敏之、上村浩一．看護師と他の就労女性における更年期症状に対する対処方法の違い．第30回日本女性医学学会学術集会．2015年11月7日～8日、名古屋

高橋久美、安井敏之、上村浩一．交代勤務制を行う看護師の月経周期の規則性と睡眠．第30回日本女性医学学会学術集会．2015年11月7日～8日、名古屋

松井寿美佳, 安井敏之, 笠井可菜，毛山薫, 加藤剛志, 上村浩一, 苛原稔．エストロゲンの投与ルートによる男性ホルモンの変化の違いについての検討．第30回日本女性医学学会学術集会．2015年11月7日～8日、名古屋

毛山薫,安井敏之, 笠井可菜, 松井寿美佳，加藤剛志, 上村浩一, 苛原稔．閉経期女性における脂質代謝と男性ホルモン．第30回日本女性医学学会学術集会．2015年11月7日～8日、名古屋

毛山薫, 松井寿美佳，安井敏之, 笠井可菜,加藤剛志, 上村浩一, 苛原稔．周閉経期女性における脂質代謝と男性ホルモン．第68中国四国産科婦人科学会総会ならびに学術講演会．2015年9月5日～6日、倉敷

松井寿美佳, 安井敏之, 毛山薫, 加藤剛志, 上村浩一, 苛原稔．超低用量ホルモン補充療法は閉経後女性における動脈硬化度を改善する．第67回日本産科婦人科学会学術講演会．2015年4月10日～12日、横浜．

上村浩一、山口美輪、釜野桜子、有澤孝吉、J-MICC Study Group．Clock遺伝子多型と糖尿病有病との関連について：J-MICC Studyより．第85回日本衛生学会学術総会．2015年3月26日～28日、和歌山．

有澤孝吉、永井香絵、針田哲、苣木洋一、泥谷真樹、松村徹、上村浩一、釜野桜子、山口美輪.日本人におけるダイオキシン類の血中濃度ならびに摂取量の減少傾向（2002年～2013年）. 第85回日本衛生学会総会. 平成27年3月27～28日、和歌山.