Development of the 4'-thiomodified siRNAs against SARS-CoV-2
〇Yuhei Nogi, Noriko Saito-Tarashima, Takaaki Koma, Masako Nomaguchi, Noriaki Minakawa
14th AFMC International Medicinal Chemistry Symposium (AIMECS 2023) (Poster presentation)
Jun 25-28, 2023, Conrad Hotel (Seoul Korea)
2022年度
Transfusion of mouse B cells, embedded antigens with hydroxyl PEG-modified liposomes in vitro, induces cellular immune responses in mice
〇Yoshino Kawaguchi, Taro Shimizu, Hidenori Ando, Yu Ishima, Tatsuhiro Ishida
15th International Symposium on Nanomedicine (ISNM2022) (Poster presentation)
Dec 6-8, 2022, Tokushima University (Tokushima Japan)
Oral sodium bicarbonate enhances accumulation and antitumor effects of PEGylated liposomal doxorubicin (Doxil®)
〇Nana Cristina Amorim Matsuo, Hidenori Ando, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida
15th International Symposium on Nanomedicine (ISNM2022) (Poster presentation)
Dec 6-8, 2022, Tokushima University (Tokushima Japan)
Preparation, optimization, and evaluation of anionic DPPG-based LNPs for delivery of peptide antigens
〇Eslam Ramadan, Hidenori Ando, Haruka Yamamoto, Mako Fukumoto, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida
15th International Symposium on Nanomedicine (ISNM2022) (Poster presentation)
Dec 6-8, 2022, Tokushima University (Tokushima Japan)
The mechanism investigation of intestinal absorption enhancement of drugs using ionic liquids
〇Shoichiro Fukuda, Hidenori Ando, Atsuya Maruyama, Takashi Nakae, Noboru Tatsumi, Hidetoshi Hamamoto, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida
15th International Symposium on Nanomedicine (ISNM2022) (Poster presentation)
Dec 6-8, 2022, Tokushima University (Tokushima Japan)
Neutralization of acidic tumor microenvironment by dosing of sodium potassium citrate (K/Na citrate) enhances antitumor effects of Abraxane®
〇Riku Uehara, Hidenori Ando, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida
15th International Symposium on Nanomedicine (ISNM2022) (Poster presentation)
Dec 6-8, 2022, Tokushima University (Tokushima Japan)
Differential organ-specific distribution of human serum albumin denatured by various modifications
〇Aiko Hashimoto, Yu Ishima, Taro Shimizu, Hidenori Ando, Tatsuhiro Ishida
15th International Symposium on Nanomedicine (ISNM2022) (Poster presentation)
Dec 6-8, 2022, Tokushima University (Tokushima Japan)
An ionic liquids-based topical antitumor vaccine: a mechanism for induction of antitumor immunity via topical application of cancer-antigen peptides
〇Takaaki Matsuzaki, Taro Shimizu, Hidenori Ando, Yu Ishima, Katsuhiro Yamanaka, Hidetoshi Hamamoto, Tatsuhiro Ishida
15th International Symposium on Nanomedicine (ISNM2022) (Poster presentation)
Dec 6-8, 2022, Tokushima University (Tokushima Japan)
Development of a novel technique for antibody induction against membrane proteins by spleen immunization with membrane protein-loaded PEG-modified liposomes
〇Shunto Yamamoto, Hidenori Ando, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida
15th International Symposium on Nanomedicine (ISNM2022) (Poster presentation)
Dec 6-8, 2022, Tokushima University (Tokushima Japan)
Induction of neutralizing antibodies by immunization with inactivated human TNF-alpha in mice
〇Haruka Yamamoto, Hidenori Ando, Yasukazu Omoto, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida
15th International Symposium on Nanomedicine (ISNM2022) (Poster presentation)
Dec 6-8, 2022, Tokushima University (Tokushima Japan)
Synthesis and physical/enzymatic behaviors of the DNA oligomer possessing an ambiguous base, 5-aminoimidazole-4-carboxamide
〇Yuhei Nogi, Noriko Saito-Tarashima, Noriaki Minakawa
The 49th International Symposium on Nucleic Acids Chemistry / The 6th Annual Meeting of Japan Society of Nucleic Acids Chemistry (ISNAC2022) (Poster presentation)
Nov 2-4, 2022, Tokyo University of Science (Tokyo Japan)
Biological roles of supersulfide in human hair
〇Takeru Hirai, Nanami Tasaka, Hidenori Ando, Taro Shimizu, Tatsuhiro Ishida, Yu Ishima
Redox Week in Sendai 2022 (Poster presentation)
Oct 28- Nov 1, 2022, Tohoku University Seiryo Campus (Sendai Japan)
2021年度
Synthesis of 4'-thiomodified cyclic dinucleotide analogs as STING agonists
〇Mao Kinoshita, Noriko Saito-Tarashima, Noriaki Minakawa
AFMC International Medicinal Chemistry Symposium 2021 (AIMECS2021) (Poster presentation)
Nov 29- Dec 2, 2021, On line
The induction level of anti-PEG IgM by PEGylated liposomes depends on the route of administration and the presence of nucleic acids
〇Haruka Takata, Taro Shimizu, Hiro Ueda, Hidenori Ando, Yu Ishima, Tatsuhiro Ishida
14th International Symposium on Nanomedicine (ISNM2021) (Poster presentation)
Nov 17-19, 2021, On line
Human serum albumin (HSA)-based nanocarriers efficiently deliver antigens to the spleen and induce antigen-specific humoral immunity
〇Rina Yamade, Taro Shimizu, Naoki Hirakawa, Hidenori Ando, Yu Ishima, Tatsuhiro Ishida
14th International Symposium on Nanomedicine (ISNM2021) (Poster presentation)
Nov 17-19, 2021, On line
Chemical synthesis and evaluation of 4'-thiomodified cyclic dinucleotides
〇Mao Kinoshita, Noriko Saito-Tarashima, Noriaki Minakawa
The 48th International Symposium on Nucleic Acids Chemistry / The 5th Annual Meeting of Japan Society of Nucleic Acids Chemistry (ISNAC2021) (Poster presentation)
Nov 10-12, 2021, On line
Synthesis and Properties of 4'-ThioLNA/BNA
〇Toshiki Miyazawa, Rion Maeda, Noriko Saito-Tarashima, Yuichi Yoshimura, Noriaki Minakawa
The 48th International Symposium on Nucleic Acids Chemistry / The 5th Annual Meeting of Japan Society of Nucleic Acids Chemistry (ISNAC2021) (Poster presentation)
Nov 10-12, 2021, On line
2019年度
Synthesis of cyclic-di-ZMP
〇Yusuke Kumanomido, Noriko Saito-Tarashima, Noriaki Minakawa
The 46th International Symposium on Nucleic Acids Chemistry / The 3rd Annual Meeting of Japan Society of Nucleic Acids Chemistry (ISNAC2019) (Poster presentation)
Oct 29-31, 2019, Miyaji Gakki Hall (Tokyo Japan)
Gene therapy with lipoplexes may worsen inflammation via formation of immune complexes with the pre-existing anti-DNA antibodies in SLE
〇Haruka Takata, Taro Shimizu, Tatsuhiro Ishida
Liposome Research Days 2019 (LRD2019) (Poster presentation)
Sep 15-18, 2019, Hokkaido University Conference Hall (Sapporo Japan)
Enhanced therapeutic efficacy of liposomal weak-base anticancer drugs by daily oral administration of sodium bicarbonate
〇Maho Tagami, Hidenori Ando, Ai Ikeda, Kiyoshi Eshima, Cheng-Long Huang, Hiromi Wada, Tatsuhiro Ishida
Liposome Research Days 2019 (LRD2019) (Poster presentation)
Sep 15-18, 2019, Hokkaido University Conference Hall (Sapporo Japan）
Immunization method to obtain antigen-specific antibodies by antigen delivery to splenic marginal zone B cells using PEGylated liposomes
〇Yuna Shimazaki, Hidenori Ando, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida
Liposome Research Days 2019 (LRD2019) (Poster presentation)
Sep 15-18, 2019, Hokkaido University Conference Hall (Sapporo Japan)
2018年度
Sphingosine-1-phosphate (S1P) affects the secretion of high density lipoprotein (HDL)-constituent protein
〇Kouki Tachibana, Tamotsu Tanaka, Kentaro Kogure, Tatsuhiro Ishida, Keiichiro Okuhira
12th International Symposium on Nanomedicine (ISNM2018) (Oral presentation)
Dec 6-8, 2018, Kogushi Campus in Yamaguchi University (Ube Japan)
Creation of a puDDD: pyAAA H-bonding base pair in DNA oligonucleotide
〇Koki Matsumoto, Noriko Saito-Tarashima, Noriaki Minakawa
ISNAC2018 (Poster Presentation)
Nov 7-9, 2018, Kyoto University Clock Tower Centennial Hall (Kyoto Japan)
Elucidating dynamic interactions between siRNA and proteins using a pair of nucleoside chemical probes
〇Tomoya Wada, Mayu Yamada, Noriko Saito-Tarashima, Noriaki Minakawa
The 23rd International Roundtable of Nucleosides, Nucleotides and Nucleic Acids (IRT 2018) (Poster presentation)
Aug 26-30, 2018, The University of California (San Diego)
The effect of liposome co-incubation with cancer cells on the secretion, uptake propensity and expression of certain surface proteins of cancer cell-derived exosomes (extracellular vesicles)
〇Sherif Emam Abdallah Emam, Hidenori Ando, Lila Selim Ahmed Ali Abu Amr, Yu Ishima, A M Mahdy, S F Ghazy, Tatsuhiro Ishida
2018 CRS Annual Meeting & Exposition (Poster presentation)
July 21-24, 2018, New York Hilton Midtown Manhattan Hotel (New York)
Reactive Sulfur Species in Human Hair Keratin Respond To Oxidative Stress
〇Nanami Tasaka, Mayumi Ikeda, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida
5th World Congress on Hydrogen Sulfide in Biology & Medicine (Poster presentation)
May 31-June 3, 2018, Intercontinental Yorkville Hotel (Toronto)
A Novel S-Sulfhydrated Human Serum Albumin Preparation Suppresses Melanin Synhtesis
〇Mayumi Ikeda, Nanami Tasaka, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida
5th World Congress on Hydrogen Sulfide in Biology & Medicine (Poster presentation)
May 31-June 3, 2018, Intercontinental Yorkville Hotel (Toronto)
2017年度
Synthesis and properties of 4'-selenoRNA
〇Masashi Ota, Noriko Saito-Tarashima, Noriaki Minakawa
ISNAC2017 (Poster presentation)
November 14-16, 2017, Tokyo University of Science (Tokyo Japan)
Investigation on antitumor effect and systemic toxicity by repeated injection of thermosensitive liposome encapsulating doxorubicin (ThermoDox®)
〇Takuma Maitani, Masami Ukawa, Satoru Ishii, Gou Nohara, Hikaru Abutani, Nicholas Anderson, Tatsuhiro Ishida
ILS Liposome Advances and Liposome Research Days Combined Conference (Poster presentation)
September 16-18, 2017, Royal Olympic Hotel (Athens)
2015年度
Targeted gene silencing by introduction of intelligent RNA expression device (iRed)
〇Nozomi Kinjo, Hidenori Ando, Noriko Tarashima, Noriaki Minakawa, Tatsuhiro Ishida
Liposome Advances 2015 (Poster presentation)
December 19-22, 2015, UCL School of Pharmacy, University of London (London)
Liposomal doxorubicin (DXR) exerts antitumor effect via securing antitumor immunity against DXR in tumor microenvironment
〇Takuma Takayama, Taro Shimizu, Masami Ukawa, Tatsuhiro Ishida
Liposome Advances 2015 (Poster presentation)
December 19-22, 2015, UCL School of Pharmacy, University of London (London)
Anti-PEG IgM production induced by siRNA-containing PEGylated liposome
〇Yuka Kitayama, Ryo Abe, Taro Shimizu, Tatsuhiro Ishida
Liposome Advances 2015 (Poster presentation)
December 19-22, 2015, UCL School of Pharmacy, University of London (London)
Altering PEGylated liposomes modification from DSPE-PEG-OCH3 to DSPE-PEG-OH suppresses secretion of anti-PEG IgM and proliferation of PEG-specific B cells
〇Mizuki Awata, Risako Fujita, Yu Mima, Munehira Kawanishi, Taro Shimizu, Tatsuhiro Ishida
Liposome Advances 2015 (Poster presentation)
December 19-22, 2015, UCL School of Pharmacy, University of London (London)
Development of a Minimally-Sized DNA Vector for Gene Silencing using an Unnatural Base Pair Analog Having Four Hydrogen Bonds
〇Noriko Tarashima, Noriaki Minakawa
AIMECS 2015(10th AFMC International Medicinal Chemistry Symposium in 2015) (Poster presentation)
Octover 18-21, 2015, International Convention Center (ICC) JEJU (Korea)
Gene silencing via RNA interference (RNAi) machinery using 4'-thioDNA as an artificial template
〇Noriko Tarashima, Nozomi Kinjyo, Takamitsu Kojima, Hidenori Ando, Tatsuhiro Ishida, Noriaki Minakawa
The 42nd International Symposium on Nucleic Acids Chemistry (Oral presentation)
September 23-25, 2015, I-messae hall (Himeji Japan)
2014年度
Arginine-glycosaminoglycan Interaction Regulates Penetration Efficiency of Arginine-rich Cell-penetrating Peptides in Biological Membrane
〇Yuki Takechi(Haraya), Yuto Yanagisawa, Kazuchika Nishitsuji, Kenji Utimura, Toru Kawakami, Kohsaku Kawakami, Keiichiro Okuhira, Hiroyuki Saito
Biophysical Society 59th Annual Meeting (Poster presentation)
February 7-11, 2015, The Baltimore Convention Center (Baltimore)
Synthesis and Properties of a novel 1,2-dithianenucleoside
〇Tadashi Miyazawa, Noriko Tarashima, Kazuhiro Furukawa, Noriaki Minakawa
The 41st International Symposium on Nucleic Acids Chemistry (Poster presentation)
November 5-7, 2014, Kitakyushu International Conference Center (Kitakyusyu Japan)
A convenient RNA purification method with a combination of click chemistry and a photolabile group
〇Kazuyuki Sagara, Noriko Tarashima, Kazuhiro Furukawa, Noriaki Minakawa
The 41st International Symposium on Nucleic Acids Chemistry (Poster presentation)
November 5-7, 2014, Kitakyushu International Conference Center (Kitakyusyu Japan)
The effect of intrapleural environment and physicochemical properties of liposome/lipoplex on its retention time after intrapleural injection
〇Chihiro Kato, Abu Lila Amr Selim, Tatsuhiro Ishida
Liposome Research Days 2014 (Poster presentation)
August 4-7, 2014, Copenhagen Business School (Denmark)
Antigen delivery with PEGylated liposome and presentation via MZ-B cells enhanced induction of antigen-specific cytotoxic T lymphocyte
〇Taro Shimizu, Yuki Watanabe, Yu Mima, Tatsuhiro Ishida, Hiroshi Kiwada
Liposome Research Days 2014 (Poster presentation)
August 4-7, 2014, Copenhagen Business School (Denmark)
Influence of retention time of liposome in thoracic cavity and release rate of Pemetrexed encapsulated in it for malignant pleural methothelioma therapy
〇Sakiko Kobayashi, Amr S. Abu-Lila, Tatsuhiro Ishida
Liposome Research Days 2014 (Poster presentation)
August 4-7, 2014, Copenhagen Business School (Denmark)
Comprehensive analysis of proteins bound on PEGylated liposome relating to the accelerated blood clearance (ABC) phenomenon by shotgun analysis
〇Munehira Kawanishi, Yosuke Hashimoto, Taro Shimizu, Ikuko Sagawa, Tatsuhiro Ishida, Hiroshi Kiwada
Liposome Research Days 2014 (Poster presentation)
August 4-7, 2014, Copenhagen Business School (Denmark)
Increased PEG-coated liposomal l-OHP accumulation in the liver relates antitumor effect against M5076 ovarian sarcoma liver metastasis
〇Yukako Fujiwara, Hiroyuki Nakamura, Tatsuhiro Ishida, Hiroshi Kiwada
Liposome Research Days 2014 (Poster presentation)
August 4-7, 2014, Copenhagen Business School (Denmark)
Inclusion of ganglioside into PEGylated liposome suppresses the anti-PEG immunity against PEGylatedliposome
〇Yu Mima, Taro Shimizu, Hiroshi Kiwada, Tatsuhiro Ishida
Liposome Research Days 2014 (Poster presentation)
August 4-7, 2014, Copenhagen Business School (Denmark)
Long interval between Doxil® treatments causes Doxil® resistance in Colon26-bearing mouse
〇Kosuke Takahashi, Miho Nishio, Tatsuhiro Ishida
Liposome Research Days 2014 (Poster presentation)
August 4-7, 2014, Copenhagen Business School (Denmark)
