2023年

原著論文

1. 1,3a,6a-Triazapentalene derivatives as photo-induced cytotoxic small fluorescent dyes
   D. Tsuji, A. Nakayama, Y. Yamamoto, S. Nagano, T. Taniguchi, R. Sato, S. Karanjit, N. Muguruma, T. Takayama, K. Itoh, K. Namba. Commun. Chem. 2023, 6, 37. [link]   
   
   
    
2. Suitable stereoisomers of vibrioferrin probes for iron uptake of Vibrio parahaemolyticus
   R. Sumida, M. Okuda, A. Mera, M. Inoue, S. Karanjit, K. Niwa, T. Tsutusmi, R Sato, A. Nakayama, N. Tanaka, M. Oda, K. Namba. Chem. Lett. 2023, Advance Publication [link]
   
   
    
3. A simple and powerful tert-butylation of carboxylic acids and alcohols.
   C. Ogasa, K. Kayano, K. Namba. Synlett, 2023, accepted article. [Link]
   
4.  
5.  

2022年

原著論文

1. A heterogeneous bifunctional silica-supported Ag2O/Im+Cl− catalyst for efficient CO2 conversion
   S. Karanjit, E. Tanaka, L. K. Shrestha, A. Nakayama, K. Ariga, K. Namba. Cata. Sci. Technol. 12, 3778-3785 (2022).  [Link]
   
    
2. Total Syntheses of Proposed Structures of 4,10-Dihydroxy-8,12-guaianolides.
   Y. Kimura, E. Ohashi, S. Karanjit, T. Taniguchi, A. Nakayama, H. Imagawa, R. Sato, K. Namba. Org. Lett. 24, 3297-3301 (2022). [Link]
   
    
3. Uptake mechanism of iron-phytosiderophore from the soil based on the structure of yellow stripe transporter.
   A. Yamagata, Y. Murata, K. Namba, T. Terada, S. Fukai, M. Shirouzu. Nature Communications. 13, 7180 (2022). [link]

2021年

原著論文

1. Concise Total Synthesis of Tronocarpine.
   A. Nakayama, T. Nakamura, T. Zaima, S. Fujimoto, S. Karanjit, K. Namba. Angew. Chem. Int. Ed. 60, 635-639 (2021). [Link]
   
2. Development of a mugineic acid family phytosiderophore analog as an iron fertilizer
   M. Suzuki, A. Urabe, S. Sasaki, R. Tsugawa, S. Nishio, H. Mukaiyama, Y. Murata, H. Masuda, M. Sann Aung, A. Mera, M. Takeuchi, K. Fukushima, M. Kanaki, K. Kobayashi, Y. Chiba, B. B. Shrestha, H. Nakanishi, T. Watanabe, A. Nakayama, H. Fujino, T. Kobayashi, K. Tanino, N. K. Nishizawa, K. Namba. Nature Communications, 12, 1558 (2021).[Link]
   
3. Development of a novel antioxidant based on a dimeric dihydroisocoumarin derivative
   A. Nakayama, T. Nakamura, T. Ara, T. Fukuta, S. Karanjit, T. Harada, A. Oda, H. Sato, M. Abe, K. Kogure, K. Namba . Tetrahedron Lett. 74, 153176 (2021). [Link]
   
   
    
4. Efficient construction of the hexacyclic ring core of palau'amine: the pKa concept for proceeding with unfavorable equilibrium reactions
   E. Ohashi, S. Karanjit, A. Nakayama, K. Takeuchi, S. E. Emam, H. Ando, T. Ishida, K. Namba. Chemical Science, 2021, 12, 12201-12210. [Link]
   

2020年

原著論文

1. Development of a 1,3a,6a-triazapentalene derivative as a compact and thiol-specific fluorescent labeling reagent;
   A. Nakayama, A. Otani, T. Inokuma, D. Tsuji, H. Mukaiyama, A. Nakayama, K. Itoh, A. Otaka, K. Tanino, K. Namba. Commun Chem., 3, 6 (2020).[Link]
   
    
2. Synthesis and Antimicrobial Evaluation of Side-Chain Derivatives based on Eurotiumide A. 
   T. Nakamura, M. Hamada, S. Nagano, S. Kameyama, Y. Furue, N. Hayashi, G. Kamoshida, S. Karanjit, M. Oda, K. Namba. Marine Drugs, 18, 92 (2020).[Link]
   
    
3. Synthesis and evaluation of 1,1,7,7-tetramethyl-9-azajulolidine (TMAJ) as a highly active derivative of N,N-dimethylaminopyridine.
   T. Tsutsumi, A. Saitoh, T. Kasai, M.-Y. Chu, S, Karanjit, A. Nakayama, K. Namba. Tetrahedron Lett. 61, 152047 (2020). [Link]
   
    
4. Total Synthesis of Epilupinine: Synthetic Strategy of Fused Bicyclic Skeleton Containing Nitrogen.
   T. Tsutsumi, K. Namba. Chem. Lett., 49(8), 963-969 (2020) [Link]
   
    
5. Hydrotalcite-Supported Ag/Pd Bimetallic Nanoclusters Catalyzed Oxidation and One-Pot Aldol Reaction in Water.
   S. Karanjit, A. Tamura, M. Kashihara, K. Ushiyama, L. K. Shrestha, K. Ariga, A. Nakayama, K. Namba. Cyatalysts, 10(10), 1120 (2020) [Link]
   

2019年

原著論文

1. Microwave-assisted Tertiary Carbon Radical Reaction for Construction of Quaternary Carbon Center;
   R. Sato, R. Okamoto, T. Ishizuka, A. Nakayama, S. Karanjit, K. Namba, Chem. Lett., 48, 414-417 (2019).[Link]
   
    
2. A Concise Asymmetric Total Synthesis of (+)-Epilupinine;
   T. Tsutsumi, S. Karanjit, A. Nakayama, K. Namba, Org. Lett., 4013-4017 (2019).[Link]
   
3. Asymmetric Total Syntheses and Structure Elucidations of (+)-Eurotiumide F and (+)-Eurotiumide G ;
   A. Nakayama, H. Sato, S. Nagano, S. Karanjit, H. Imagawa, K. Namba,Chem. Pharm. Bull, 67, 953-958 (2019).[Link]
4. 

総論・著書

1. 天然物合成が引き出す複雑天然物の力, 難波康祐, MEDCHEM NEWS, 29, 183-187 (2019).

2018年

原著論文

1. Highly active and reusable hydrotalcite-supported Pd(0) catalyst for Suzuki coupling reactions of aryl bromides and chlorides;
   K. Sangita, M. Kashihara, A. Nakayama, L. K. Shrestha, K. Ariga, K. Namba,Tetrahedron, 74, 948-954 (2018).[Link]
   
    
2. Asymmetric Total Syntheses and Structure Revisions of Eurotiumide A and Eurotiumide B, and Evaluation of their Fluorescent Properties as Natural Probes;
   A. Nakayama, H. Sato, S. Karanjit, N. Hayashi, M. Oda, K. Namba,Eur. J. Org. Chem., 4013-4017 (2018).[Link]
   
    
3. Direct Synthesis of Polycyclic Tropinones via Condensation‐(4+3) Cycloaddition Cascade Reaction;
   T. Okamoto, M. Shibata, S. Karanjit, A. Nakayama, M. Yoshida, K. Namba, Chem. Eur. J., 24, 9508-9513 (2018).[Link]
   
4. Quantitation of sevoflurane in whole blood and aqueous solutions by volatile organic compound sensing;
   Y. Hase, K. Suzuki, N. Kamekura, M. Shibuya, Y. Takahashi, K. Namba, T. Fujisawa,J. Pharmacological and Toxicological Methods, 94, 71-76 (2018).[Link]
    
5. Synthesis and Evaluation of 1,3a,6a-triazapentalene (TAP)-bonded system;
   M. Ito, A. Mera, T. Mashimo, T. Seki, S. Karanjit, E. Ohashi, A. Nakayama, K. Kitamura, T. Hamura, H. Ito, K. Namba, Chem. Eur. J., 17727-17733 (2018).[Link]
   

総論・著書

1. 第4章 連続環化反応を鍵としたpalau'amineの全合成, 難波康祐, 天然有機化合物の全合成~独創的なものづくりの反応と戦略~, 化学同人 (2018).[Link]
2. 天然物全合成から見つけた蛍光化合物-Eurotiumide類の不斉全合成と蛍光特性-, 中山淳, 有機合成化学協会誌, 76, 498-501 (2018).[Link]
3. PIになるまでの道程 人との出会い, 難波康祐, 有機合成化学協会誌, 76, 740-742 (2018).[Link]
4. Organic Chemistry Research on the Mechanistic Elucidation of Iron Acquisition in Barley;
   Kosuke Namba and Yoshiko Murata, Bio. Pharm. Bull, 41, 1502-1507 (2018).[Link]
5. Chapter 6: Kinetic Control in Natural Product Synthesis, Kosuke Namba and Eisaku Ohashi;
   Kinetic Control in Synthesis and Self-assembly, ELSEVIER book [Link]

2017年

原著論文

1. Development of 1,3a,6a-triazapentalene-labeled enterobactin as a fluorescence quenching sensor of iron ion
   T. Hayashi, A. Osawa, T. Watanabe, Y. Murata, A. Nakayama, K. Namba, Tetrahedron Lett., 58, 1961-1964 (2017) [Link]
   
    
2. Synthesis of 2,6-Disubstituted-1,3a,6a-Triazapentalenes and Their Fluorescence Properties
   A. Mera, M. Ito, A. Nakayama, K. Namba, Chem. Lett., 46, 539-542 (2017) [Link]
   
    

総論・著書

1. Total Synthesis of Palau'amine
   K. Namba, K. Takeushi, Y. Kaihara, K. Tanino,J. Synth. Org. Chem., Jpn., 75, 1094-1101 (2017)[Link]

2016年

原著論文

1. Functional 1,3a,6a-triazapentalene scaffold: Design of fluorescent probes for kinesin spindle protein (KSP)
   J. Sawada, A. Osawa, T. Takeuchi, M. Kaneda, S. Oishi, N. Fujii, A. Asai, K. Tanino, K. Namba, Bioorg. Med. Chem. Lett., 26,5765-5769 (2016) [Link]
2. Effective Cellular Morphology Analysis for Differentiation Processes by a Fluorescent 1,3a,6a-Triazapentalene Derivative Probe in Live Cells
   R. Kamada, F. Tano, F. Kudoh, N. Kimura, Y. Chuman, A. Osawa, K. Namba, K. Tanino, PLOSone, 11,e0160625 (2016) [Link]
3. Facile Guanidine Formation under Mild Acidic Conditions.
   K. Takeuchi, A. Nakayama, K. Tanino, K. Namba, Synlett, 27, 2591-2596 (2016) [Link]
4. Direct cyclization of 1,3-diaryl propargylic alcohols with β-dicarbonyl compounds by palladium-boric acid dual-catalyst system.
   M. Yoshida, S. Ohno, S. Eguchi, T. Mizuguchi, K. Matsumoto, K. Namba, Tetrahedron., 72, 5633-5639 (2016) [Link]
5. Substituent Effect at the C4-Position of 1,3a,6a-Triazapentalene.
   A. Nakayama, S. Nishio, A. Otani, A. Mera, A. Osawa, K. Tanino, K. Namba, Chem. Pharm. Bull., 64, 830-837 (2016) [Link]
6. Synthesis of functionalized 2,3-dihydropyrroles by oxidative radical cyclization of N-Sulfonyl β-enamino esters with alkenes.
   M. Yoshida, A. Kobayashi, A. Nakayama, K. Namba Tetrahedron, 72, 2544-2551 (2016) [Link]

2015年

原著論文

1. Total Synthesis of Palau'amine
   K. Namba, K. Takeuchi, Y. Kaihara, M. Oda, A. Nakayama, A. Nakayama, M. Yoshida, K. Tanino, Nature Communications, 6:8731 (2015) [Link]
   
2. Acid-catalyzed [4+3] cycloaddition reaction of N-nosyl pyrroles.
   M. Shibata, R. Fuchigami, R. Kotaka, K. Namba, K. Tanino, Tetrahedron, impress (2015) [Link]
   
3. Total Syntheses and Initial Evaluation of [Ψ[C(═S)NH]Tpg4]vancomycin, [Ψ[C(═NH)NH]Tpg4]vancomycin, [Ψ[CH2NH]Tpg4]vancomycin, and Their (4-Chlorobiphenyl)methyl Derivatives: Synergistic Binding Pocket and Peripheral Modifications for the Glycopeptide Antibiotics.
   A. Okano , A. Nakayama , K. Wu , E. A. Lindsey , A. W. Schammel , Y. Feng , K. C. Collins , D. L. Boger, J. Am. Chem. Soc., 137, 3693-3704 (2015) [Link]
   
4. Synthesis of Yellow and Red Fluorescent 1,3a,6a-Triazapentalene and Theoretical Investigation of Optical Properties.
   K. Namba, A. Osawa, A. Nakayama, A. Mera, F. Tano, Y. Chuman, E. Sakuda, T. Taketsugu, K. Sakaguchi, N. Kitamura, K. Tanino, Chem. Sci., 6, 1083-1093 (2015) [Link]
   
5. 2'-Deoxymugineic acid promotes growth of rice (Oryza sativa L.) by orchestrating iron and nitrate uptake processes under high pH conditions.
   R. Araki, K. Kousaka, K. Namba, Y. Murata, J. Murata, Plant. J., 81, 233-246 (2015) [Link]

2014年

原著論文

1. One-pot synthesis of tri- and tetrasubstituted pyridines by sequential ring-opening/cyclization/oxidation of N-arylmethyl 3-aziridinylpropiolate esters.
   M. Yoshida, T. Mizuguchi, K. Namba, Angew. Chem. Int. Ed., 53, 14550-14554 [Link]
   
2. N-Acyl-N-tosylhydrazine as a Synthon To Construct Tetrasubstituted Carbon Centers Possessing a Nitrogen Group.
   K. Namba, Y. Shobo, K. Fujimoto, I. Shoji, M. Yoshida, K. Tanino, Eur. J. Org. Chem, in press. [Link]
   
3. Total synthesis of (-)-HM-3 and (-)-HM-4 utilizing a palladium-catalyzed addition of an arylboronic acid to an allenic alcohol followed by Eschenmoser-Claisen rearrangement.
   M. Yoshida, T. Kasai, T. Mizuguchi, K. Namba, Synlett, 25, 1160-1162 (2014) [Link]
   
4. Synthesis of functionalized 2-vinyl-2,3-dihydropyrroles and 3-methylene-1,2,3,4-tetrahydropyridines by palladium-catalyzed cyclization of ß-enaminocarbonyl compounds with allylic bisacetates.
   M. Yoshida, K. Kinoshita, K. Namba, Org. Biomol. Chem., 12, 2394-2403 (2014) [Link]
   

2013年

原著論文

1. Synthesis of substituted tetrahydrocyclobuta[b]benzofurans by palladium-catalyzed substitution/[2+2] cycloaddition of propargylic carbonates with 2-vinylphenols.
   M. Yoshida, S. Ohno, K. Namba, Angew. Chem. Int. Ed., 52, 13597-13600 (2013) [Link]
   
2. Transformations of 1-(Oxiranylmethyl)-1,2,3-triazoles into 2-(Oxiranylmethyl)-1,2,3-triazoles and Alkanenitriles.
   A. Osawa, A. Mera, K. Namba, K. Tanino, Synlett, 207-210 (2013) [Link]
   

2012年

原著論文

1. Concise [4+3] cycloaddition reaction of pyrroles leading to tropinone derivatives.
   R. Fuchigami, K. Namba, K. Tanino, Tetrahedron Lett., 53, 5725-5728 (2012) [Link]
   
    
2. One-pot Synthesis of Highly Fluorescent 2,5-Disubstituted-1,3a,6a-triazapentalene.
   K. Namba, A. Mera, A. Osawa, E. Sakuda, N. Kitamura, K. Tanino, Organic Letters, 14, 5554-5557 (2012) [Link]
   
    
3. Hg(OTf)2-Catalyzed Vinylogous Semi-Pinacol Rearrangement Leading to 1,4-Dihydroquinolines.
   K. Namba, M. Kanaki, H. Suto, M. Nishizawa, K. Tanino, Organic Letters, 14, 1222-1225 (2012) [Link]
   
    
4. Carbon-Nitrogen Bond Formation Between Allyl Silyl Ether and Hydrazide Promoted by Mercuric Triflate Catalyst.
   H. Yamamoto, N. Yamasaki, S. Yoshidome, I. Sasaki, K. Namba, H. Imagawa, M. Nishizawa, Synlett, 1069-1073 (2012) [Link]
   

総論・著書

1. Total Synthesis of Manzacidins. An Overview and Perspective.
   Y. Ohfune, K. Oe, K. Namba, T. Shinada, Heterocycles, 85, 2617-2649 (2012) [Link]
   ]

2011年

原著論文

1. Direct Synthesis of Fluorescent 1,3a,6a-Triazazapentalene Derivatives via Click-Cyclization-Aromatization Cascade Reaction.
   K. Namba, A. Osawa, S. Ishizaka, N. Kitamura, K. Tanino, J. Am. Chem. Soc., 133, 11466-11469 (2011) [Link]
   

総論・著書

1. 野崎-檜山-岸反応(NHK)反応.
   早川一郎, 難波康祐
   化学同人, 2011年10月

2010年

原著論文

1. Synthetic Studies on Palauamine. Construction of the Cyclopentane Core via an Asymmetric [1,3]-Dipolar Cycloaddition.
   K. Namba, M. Inai, U. Sundermeier, Robert M. Williams,* Tetrahedron Letters, 51, 6557-6559 (2010) [Link]
   
    
2. Hg(OTf)2-BINAPHANE-Catalyzed Enantioselective Anilino Sulfonamide Allyl Alcohol Cyclization.
   H. Yamamoto, E. Ho, K. Namba, H. Imagawa, M. Nishizawa, Chem. Eur. J., 16, 11271-11274 (2010) [Link]
   
    
3. Hg(OTf)2-Catalyzed Cycloisomerization of Aryl- and Hetero- Substituted 1,3-Dienes.
   M. Nishizawa, S. Shiomi, D. Odate, I. Sasaki, K. Namba, H. Yamamoto, H. Imagawa, Chemistry Letters, 39, 830-831 (2010) [Link]
   
    
4. Development of Mugineic Acid as a Molecular Probe for the Mechanistic Elucidation of Iron Acquistion in Barley.
   K. Namba, K. Kobayashi, Y. Murata, H. Hirakawa, T. Yamagaki, T. Iwashita, M. Nishizawa, S. Kusumoto, K. Tanino, Angew. Chem. Int. Ed., 49, 9956-9959 (2010) [Link]
   

総論・著書

1. Toward Mechanistic Elucidation of Iron Acquisition in Barley: Efficient Synthesis of Mugineic Acids and Their Transport Activities.
   K. Namba, Y. Murata, Chemical Record, 10, 140-150 (2010) [Link]
   ]

2009年

原著論文

1. Toward Palauamine; Hg(OTf)2-Catalyzed Synthesis of Cyclopentane Core.
   K. Namba, Y. Kaihara, H. Yamamoto, H. Imagawa, K. Tanino, R. M. Williams, M. Nishizawa, Chem. Eur. J., 15, 6560-6563 (2009) [Link]
   
    
2. 4-Aminopyridines-Catalyzed Direct and Regioselective Acylation of N-Tosylhydrazide.
   K. Namba, I. Shoji, M. Nishizawa, K. Tanino, Organic Letters, 11, 4970-4973 (2009) [Link]
   
    
3. Hg(OTf)2-Catalyzed Instantaneous Hydration of and -Hydroxy Internal Alkynes with Complete Regioselectivity.
   M. Nishizawa, T. Takemoto, I. Sasaki, M. Nakano, E. Ho, K. Namba, H. Yamamoto, H. Imagawa, Synlett, 1175-1179 (2009) [Link]
   
    
4. Silaphenylmercuric Triflate-Catalyzed Reactions: The First Solid Supported Mercuric Salt Catalyst.
   H. Yamamoto, I. Sasaki, Y. Hirai, K. Namba, H. Imagawa, M. Nishizawa, Angew. Chem. Int. Ed., 48, 1244-1247 (2009) [Link]
   
    
5. Attempts to Improve the Overall Stereoselectivity of Ireland-Claisen Rearrangemen.
   C-L. Chen, K. Namba, Y. Kishi, Organic Letters, 11, 409-412 (2009) [Link]
   

原著論文

1. Efficient Glycosylation Using ODS Adsorption Method Based on the Affinity of Long Alkoxybenzyl Glycoside.
   H. Imagawa, A. Kinoshita, H. Yamamoto, K. Namba, M. Nishizawa, Synlett, 1981-1984 (2008) [Link]
   
    
2. Hg(OTf)2-Catalyzed Cyclization of N-Tosylanilinoallylic Alcohols Leading 2-Vinyindolines.
   K. Namba, Y. Nakagawa, H. Yamamoto, H. Imagawa, M. Nishizawa, Synlett, 10, 1719-1723 (2008) [Link]
   
    
3. Hg(OTf)2-Catalyzed Aryl Allyl Alcohol Cyclization.
   K. Namba, H. Yamamoto, I. Sasaki, K. Mori, H. Imagawa, M. Nishizawa, Organic Letters, 10, 1767-1770 (2008) [Link]
   
    
4. A specific transporter for iron (III)-phytosiderophore complex involved iron acquisition by bareley roots.
   Y. Murata, E. Harada, K. Sugase, K. Namba, M. Horikawa, J.-F. Ma, N. Yamaji, D. Ueno, K. Nomoko, T. Iwashita, S. Kusumoto, Pure Appl Chem, 80, 2689-2697 (2008) [Link]
    

原著論文

1. Structural element responsible for the Fe(III)-specific transport as phytosiderophore complex by HvYS1 transporter of barley.
   E. Harada, K. Sugase, K. Namba, T. Iwashita, M. Yoshiko,* FEBS Letters, 581, 4298-4302 (2007) [Link]
    
2. Virtually Complete E-Selective -Unsaturated Ester Synthesis by Hg(OTf)2-Catalyzed Hydration of sec-Ethoxyalkynyl Acetate.
    Organic Letters, 9,  [Link]
   
3. Catalytic Activation of the Leaving Group in the SN2 Reaction.
   H. Yamamoto, G. Pandey, Y. Asai, M. Nakano, A. Kinoshita, K. Namba, H. Imagawa, M. Nishizawa, Organic Letters, 9, 4029-4032 (2007) [Link]
   
    
4. A Practical Synthesis of a Phytosiderophore 2-Deoxymugineic Acid. A Key to the Mechanistic Study of Iron Acquisition by Graminaceous Plants.
   K. Namba, Y. Murata, M. Horikawa, T. Iwashita, S. Kusumoto, Angew. Chem. Int. Ed., 46, 7060-7063 (2007) [Link]
   
    
5. Total synthesis and morphogenesis-inducing activity of (±)-thallusin and its analogues.
   M. Nishizawa, T. Iyenaga, T. Kurisaki, M. Sharfuddin, K. Namba, H. Imagawa, Y. Shizuri, Y. Matsuo, Tetrahedron Letters, 48, 4229-4233 (2007) [Link]
   
    
6. Synthesis and Absolute Structure of Manzacidin B.
   T. Shinada, E. Ikebe, K. Oe, K. Namba, M. Kawasaki, Y. Ohfune, Organic Letters, 9, 1765-1767 (2007) [Link]
   

2007年以前の論文リストはこちらから

• 難波 康祐 教授