2025(ねん)

Development of a Novel Horner–Wadsworth–Emmons Reagent for the Facile Preparation of Mixed Phosphonoacetates.
M. Nakao, M. Okamoto, S. Isetani, A. Imai, S. Kitaike, and S. Sano,
SynOpen, 9 (1), 131–137 (2025).

Synthesis of Methyl 2-[Bis(benzylthio)phosphoryl]acetate as a Novel Horner–Wadsworth–Emmons-Type Reagent and Its Application to the Diastereodivergent Synthesis of (E)- and (Z)-α,β-Unsaturated Esters.
S. Sano, S. Yamada, T. Ihara, K. Seki, S. Kitaike, and M. Nakao,
Synlett, 36 (5), 546–550 (2025).

2024(ねん)

Concentration-dependence of specific rotation of optically active glycerol analogues and structurally related compounds: the significance of intermolecular hydrogen bonding.
M. Nakao, A. Nakamura, S. Yamada, S. Kitaike, and S. Sano,
Results in Chemistry, 7, 101415 (2024).

2023(ねん)

Synthesis of Novel Phosphorus-Substituted Stable Isoindoles by a Three-Component Coupling Reaction of ortho-Phthalaldehyde, 9,10-Dihydro-9-oxa-10-phosphaphenanthrene 10-Oxide, and Primary Amines.
M. Nakao, A. Nakamura, T. Takesue, S. Kitaike, H.-O. Ito, and S. Sano,
SynOpen, 7 (3), 394-400 (2023).

Efficient One-Pot, Three-Step Synthesis of 1,2,3,5-Tetrasubstituted Pyrroles via Aza-Michael Addition of Methyl 3-Iminoacrylates.
M. Nakao, K. Horikoshi, S. Kitaike, and S. Sano,
Heterocycles, 106 (8), 1397-1406 (2023).

Molecular species profiles of plasma ceramides in different clinical types of X-linked adrenoleukodystrophy.
K. Morito, R. Shimizu, H. Ali, A. Shimada, T. Miyazaki, N. Takahashi, M. M. Rahman, K. Tsuji, N. Shimozawa, M. Nakao, S. Sano, M. Azuma, M. Nanjundan, K. Kogure, and T. Tanaka,
THe Journal of Medical Investigation, 70 (3/4), 403-410 (2023).

Novel anti-myeloma therapeutic option with inhibition of the HDAC1-IRF4 axis and PIM kinase.
T. Harada, H. Ohguchi, A. Oda, M. Nakao, J. Teramachi, M. Hiasa, R. Sumitani, M. Oura, K. Sogabe, T. Maruhashi, M. Takahashi, S. Fujii, S. Nakamura, H. Miki, K. Kagawa, S. Ozaki, S. Sano, T. Hideshima, and M. Abe,
Blood Advances, 7 (6), 1019-1032 (2023).

Only one carbon difference determines the pro-apoptotic activity of α-tocopheryl esters.
M. N. Ray, M. Ozono, M. Nakao, S. Sano, and K. Kogure,
The FEBS Journal, 290 (4), 1027-1048 (2023).

2022(ねん)

Development of a novel tocopheryl ester for suppression of lipid accumulation without cytotoxicity by optimization of dicarboxylic ester moiety.
M. Yamasaki, Y. Seto, M. Ozono, M. Nakao, A. Shigenaga, A. Otaka, S. Sano, and K. Kogure,
Biochemistry and Biophysics Reports, 31, 101329 (2022). https://doi.org/10.1016/j.bbrep.2022.101329

Synthesis of Novel 2,3-Disubstituted Thiophenes via Tandem Thia-Michael/Aldol Reaction of Allenyl Esters.
M. Nakao, M. Toguchi, K. Horikoshi, S. Kitaike, and S. Sano,
Heterocycles, 104 (2), 379-388 (2022).

2021(ねん)

Catalytic Asymmetric Ring-Opening of σ-Symmetric Cyclic Carbonates with Chiral Amino Sulfonamide Catalysts.
M. Nakao, T. Shozui, D. Inoue, T. Ihara, S. Kitaike, and S. Sano,
Heterocycles, 103 (2), 1011-1022 (2021).

Indocyanine green-labeled dasatinib as a new fluorescent probe for molecular imaging of gastrointestinal stromal tumors.
S. Fujimoto, N. Muguruma, M. Nakao, H. Ando, T. Kashihara, Y. Miyamoto, K. Okamoto, S. Sano, T. Ishida, Y. Sato, and T. Takayama,
Journal of Gastroenterology and Hepatology, 36 (5), 1253-1262 (2021).

2020(ねん)

総説(そうせつ) がんを標的(ひょうてき)とした(うち)()(きょう)分子(ぶんし)イメージングの(しん)展開(てんかい)
六車(むぐるま) 直樹(なおき), 藤本(ふじもと) 将太(しょうた), 樫原(かしわら) 孝典(たかのり), (さん)(きょう) ()(こころざし), 宮本(みやもと) 佳彦(よしひこ), 岡本(おかもと) 耕一(こういち), 中尾(なかお) (まこと)(やすし), 佐野(さの) 茂樹(しげき), 高山(たかやま) 哲治(てつじ),
OPTRONICS, 39 (9), 117-121 (2020).

Tandem Thia-Michael/Dieckmann Condensation of Allenyl Esters for the Regioselective Synthesis of Trisubstituted Thiophenes.
M. Nakao, M. Toguchi, Y. Shimabukuro, and S. Sano,
Tetrahedron Letters, 61 (36), 152271. https://doi.org/10.1016/j.tetlet.2020.152271.

Synthesis of Three Stereoisomers of Erythrochelin, a Hydroxamate-type Tetrapeptide Siderophore from Saccharopolyspora erythraea.
M. Nakao, A. Adachi, S. Kitaike, and S. Sano,
Heterocycles, 101 (1), 347-356 (2020).

2018(ねん)

Facile Two-Step Synthesis of Methyl Bis(2,2,2-trifluoroethyl)phosphonoacetate by Exploiting Garegg-Samuelsson Reaction Conditions.
S. Sano, T. Matsumoto, M. Toguchi, and M. Nakao,
Synlett, 29 (11), 1461-1464 (2018).

Synthesis of Sterically Protected Isoindoles from ortho-Phthalaldehyde.
M. Nakao, N. Nishikiori, A. Nakamura, M. Miyagi, N. Shibata, S. Kitaike, M. Fukui, H.-O. Ito, and S. Sano,
SynOpen, 2 (1), 50-57 (2018).

Unique Anti-myeloma Activity by Thiazolidine-2,4-dione Compounds with Pim Inhibiting Activity.
S. Fujii, S. Nakamura, A. Oda, H. Miki, H. Tenshin, J. Teramachi, M. Hiasa, Y. Maeda, M. Oura, M. Takahashi, M. Iwasa, I. Endo, S. Yoshida, K. Aihara, K. Kurahashi, T. Harada, K. Kagawa, M. Nakao, S. Sano, and M. Abe,
British Journal of Haematology, 180 (2), 246-258 (2018).

2017(ねん)

ジケトピペラジンの分子(ぶんし)構造(こうぞう)特性(とくせい)基盤(きばん)とする機能(きのう)(せい)分子(ぶんし)創製(そうせい)
Development of Novel Functional Molecules Based on the Molecular Structure Characteristics of Diketopiperazines
中尾(なかお)(まこと)(やすし),
Michiyasu Nakao,
YAKUGAKU ZASSHI, 137 (12), 1505-1516 (2017).

Synthesis of Fluorine-Containing Analogues of 1-Lysoglycerophospholipids via Horner-Wadsworth-Emmons Reaction.
M. Nakao, K. Tanaka, S. Kitaike, and S. Sano,
Synthesis, 49 (16), 3654-3661 (2017).

Antibacterial and Antibiofilm Effects of Reuterin-Related Compounds to Periodontopathic Bacteria.
N. Fujiwara, K. Murakami, M. Nakao, M. Toguchi, H. Yumoto, K. Hirota, T. Matsuo, S. Sano, K. Ozaki, and Y. Miyake,
Journal of Oral Health and Biosciences, 30 (1), 8-17 (2017).

Novel Reuterin-Related Compounds Suppress Odour by Periodontopathic Bacteria.
N. Fujiwara, K. Murakami, M. Nakao, M. Toguchi, H. Yumoto, T. Amoh, K. Hirota, T. Matsuo, S. Sano, K. Ozaki, and Y. Miyake,
Oral Diseases, 23 (4), 492-497 (2017).

その他(そのた)論文(ろんぶん)発表(はっぴょう) * Papers

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