Professor ABE Masahiro

 Our Department focuses on the areas of hematology and endocrinology/metabolism.
 Researches in these areas include : 1）elucidation of the mechanisms of myeloma cell expansion and formation of destructive lesions in bone, and 2）development of moleculartargeted therapy against multiple myeloma, 3）elucidation of the molecular mechanisms of osteoblastic differentiation and bone formation, as well as development of bone anabolic therapy, 4）clarification of the mechanisms of the development of insulin resistance and looking up newly differentiation factor of adipose tissue 5）elucidation of the pathological interplay between cardiovascular diseases and metabolic disorders using several genetically modified mice, and development of new modalities of therapeutic agents involved in regulation of thrombin actions.