Professor TAKAYAMA Tetsuji

 Main themes of our department is to investigate molecular mechanism of initiation and progression of gastrointestinal cancers, and to develop effective drugs targeting a specific molecule for cancers. 1）Carcinogenesis of sessile serrated adenoma/polyps（SSA/Ps), 2） Cancer-adipocyte interaction in pancreatic carcinogenesis, 3）Mechanism of PIVKA-II production in hepatocellular cancer （HCC）, 4）EGFR Internalization as a predictor of anti-EGFR agents, 5）Molecular imaging of aberrant crypt foci （ACF） using GST-pi specific probe, 6）Mechanism of sorafenib resistance in HCC, 7）Angiogenic factors in ulcerative colitis tissue. We also have many research themes including plasma apheresis, capsule endoscopy and inherited colon cancer, etc.. In addition, many clinical trials are ongoing based on the results of our basic studies.