Professor SEI Hiroyoshi

  A feature of research in the field of physiology is that it is based on chronic experiments using laboratory animals. As indicated by the word “homeostasis,” in physiological research, the individual is, in principle, viewed as a whole, and even when the research is focused on a partial limited physiological function, the connection with the whole is never forgotten. From this point of view, we are trying to elucidate the brain mechanisms of higher brain functions such as sleep, emotional behavior, and/or social behavior, in relation with peripheral metabolic function in muscle, fat and/or liver. For example, we have found that chronic sleep-loss model mice cause abnormal glucose metabolism.