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Student Lab関連論文の記事を更新しました【Student Lab】

2017年10月24日

1.   Skipping of an alternative intron in the srsf1 3' untranslated region increases transcript stability.

Med. Invest. 58:180-187, 2011

Yoko Akaike1)2), Ken Kurokawa1)2), Keisuke Kajita1)2), Yuki Kuwano1), Kiyoshi Masuda1), Kensei Nishida1), Seung Wan Kang3), Toshihito Tanahashi1), and Kazuhito Rokutan1)J.

1)Department of Stress Science, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan

2)Student Lab, The University of Tokushima Faculty Medicine, Tokushima, Japan.

3)Institute of Complementary and Integrative Medicine Medical Research Center, Seoul National University, Korea

 

2.   Retinoic acid receptor antagonist LE540 attenuates wakefulness via the dopamine D1 receptor in mice.

Kazuyoshi Kitaokaa, Mika Shimizub,c, Noriyuki Shimizub, Sachiko Chikahisab,

Madoka Nakagomid, Koichi Shudod, Kazuo Yoshizakia and Hiroyoshi Séib

Brain Research. 14:10-16. 2011

aDepartment of Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan

bDepartment of Integrative Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan

cStudent Lab, The University of Tokushima Faculty of Medicine, Tokushima, Japan

dResearch Foundation Itsuu Laboratory, Tokyo, Japan

 

3.   Iron reduction by deferoxamine leads to amelioration of adiposity via the regulation of oxidative stress and inflammation in obese and type 2 diabetes

KKAy miceAmerican Journal of Physiology - Endocrinology and Metabolism. 1;302:E77-86. 2012.

Soichiro Tajima Ph.D 1,2*, Yasumasa Ikeda M.D, Ph.D 1*, Kaori Sawada 1,3, Noriko Yamano Ph.D 1, Yuya Horinouchi Ph.D 1,2, Yoshitaka Kihira Ph.D 1, Keisuke Ishizawa Ph.D 4, Yuki Izawa-Ishizawa M.D, Ph.D 1, Kazuyoshi Kawazoe Ph.D 2, Shuhei Tomita M.D, Ph.D 1, Kazuo Minakuchi Ph.D 2, Koichiro Tsuchiya Ph.D 4, Toshiaki Tamaki M.D, Ph.D 1

1) Department of Pharmacology, the University of Tokushima Graduate School of Health Biosciences

2) Department of Pharmacy, Tokushima University Hospital

3) Student Laboratory, the University of Tokushima Faculty of Medicine

4) Department of Medical Pharmacology, the University of Tokushima Graduate School of Health Biosciences

*These authors equally contributed to this work.

 

4.   Chronic exposure to an extremely low-frequency magnetic field induces depression-like behavior and corticosterone secretion without enhancement of the hypothalamic-pituitary-adrenal axis in mice.

Bioelectromagnetics 2013 Jan;34(1):43-51.

Kitaoka K 1, Kitamura M 1, Aoi S1,2, Shimizu N 3, Yoshizaki K 1.

1)Department of Physiology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan

2)Student Lab, University of Tokushima Faculty of Medicine,Tokushima, Japan

3)Department of Integrative Physiology, Institute of Health Biosciences, University of Tokushima Graduate School,Tokushima, Japan

 

5.   Rab13 small G protein and Junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development

J. Biol. Chem. 2012 Dec 14;287(51):42455-68.

Ayuko Sakane‡, Ahmed Alamir Mahmoud Abdallah‡, Kiyoshi Nakano‡§, Kazufumi Honda¶, Wataru Ikeda, Yumiko Nishikawa$, Mitsuru Matsumoto$, Natsuki Matsushita‡‡, Toshio Kitamura**, and Takuya Sasaki‡

‡Department of Biochemistry, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan,

§Student lab, The University of Tokushima Faculty of Medicine, Tokushima 770-8503, Japan,

¶Division of Chemotherapy and Clinical Research, National Cancer Center Research Institute,

Tokyo 104-0045, Japan,

KAN Research Institute, Inc., Kobe 650-0047, Japan,

$Division of Molecular Immunology, The Institute for Enzyme Research, The University of Tokushima, Tokushima 770-8503, Japan,

‡‡Functional Genomics Core-Laboratory, Ehime University Proteo-Medicine Research Center, Ehime 791-0295, Japan, and

**the Department of Hematopoietic Factor, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan

 

6.   Immunoreactivity for GABA, GAD65, GAD67 and Bestrophin-1 in the meninges and the choroid plexus:implications for non-neuronal sources for GABA in the developing mouse brain.

PLoS ONE, 8(2): e56901, 2013.

Tochitani S.1and Kondo S.1,2

1) Department of Anatomy and Developmental Neurobiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan

2) Student Lab, University of Tokushima Faculty of Medicine,Tokushima, Japan

 

7.   Prions disturb post-Golgi trafficking of membrane proteins

Nature Communications 2013;4:1846.

Keiji Uchiyama1, Naomi Muramatsu1, Masashi Yano1, Takeshi Usui1,2,

Hironari Miyata3 & Suehiro Sakaguchi1

1) Division of Molecular Neurobaiology, The Institute for Enzyme Research (KOSOKEN), The University of Tokushima, Tokushima, Japan

2) Student Lab, The University of Tokushima Faculty of Medicine,Tokushima, Japan

3) Animal Research center, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan

 

8.   Maternal Dietary Restriction Alters Offspring's Sleep Homeostasis

PLoS One. 2013 May 31;8(5):e64263

Noriyuki Shimizu1, Sachiko Chikahisa1, Yuina Nishi1,2, Saki Harada1,2, Yohei Iwaki1, Hiroaki Fujihara1, Kazuyoshi Kitaoka1, Tetsuya Shiuchi1, Hiroyoshi Se´ i1

1) Department of Integrative Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan,

2) Student Lab, University of Tokushima Faculty of Medicine, Tokushima, Japan

 

9.   HER2 amplification detected in the circulating DNA of patients with gastric cancer: a retrospective pilot study.

Gastric Cancer. 2014 Oct 17.

Shoda K1, 2, Masuda K2, Ichikawa D1, Arita T1Miyakami Y3, Watanabe M3, Konishi H1, Imoto I2, Otsuji E1.

1. Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, 465 Kawaramach Hirokoji Kajiicho, Kamigyo-ku, Kyoto, 602-8566, Japan

2. Department of Human Genetics, Institute of Health Biosciences, University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan

3. Student Laboratory, Faculty of Medicine, University of Tokushima, Tokushima, Japan

 

10.   Dietary iron restriction inhibits progression of diabetic nephropathy in db/db mice.

Am J Physiol Renal Physiol. 304: F1028–F1036, 2013.

Yasumasa Ikeda1*, Hideaki Enomoto1, 2*, Soichiro Tajima1, Yuki Izawa-Ishizawa1, Yoshitaka Kihira1, Keisuke Ishizawa3, Shuhei Tomita4, Koichiro Tsuchiya3, and Toshiaki Tamaki1

1Department of Pharmacology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan;

2Student Laboratory, Faculty of Medicine, University of Tokushima, Tokushima, Japan

3Department of Medical Pharmacology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan

4Division of Molecular Pharmacology, Tottori University, Tottori, Japan    * Y. Ikeda and H. Enomoto contributed equally to this work.

 

11.   Iron chelation by deferoxamine prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction.

PLoS ONE. 9:e89355. (2014).

Yasumasa Ikeda1, Iori Ozono1, 2, Soichro Tajima1, Mizuki Imao3, Yuya Horinouchi1, Yuki Izawa-Ishizawa1, Yoshitaka Kihira1, Rihito Miyamoto3, Keisuke Ishizawa3, Koichiro Tsuchiya3 and Toshiaki Tamaki1

1Department of Pharmacology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan;

2Student Lab, Faculty of Medicine, University of Tokushima, Tokushima, Japan

3Department of Medical Pharmacology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan

 

12.   Deletion of hypoxia-inducible factor-1α in adipocytes enhances glucagon-like peptide-1 secretion and reduces adipose tissue inflammation.

PLoS ONE. 9:e93856. (2014).

Yoshitaka Kihira1, Mariko Miyake2, Manami Hirata1, 3, Yoji Hoshina1, 3, Kana Kato4, Hitoshi Shirakawa4, Hiroshi Sakaue5, Noriko Yamano1, Yuki Izawa-Ishizawa1, Keisuke Ishizawa2, Yasumasa Ikeda1, Koichiro Tsuchiya2, Toshiaki Tamaki1 and Shuhei Tomita6

1Department of Pharmacology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan

2Department of Medical Pharmacology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan

3Student Lab, Faculty of Medicine, University of Tokushima, Tokushima, Japan

4Laboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, Miyagi, Japan,

5Department of Nutrition and Metabolism, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan,

6Division of Molecular Pharmacology, Faculty of Medicine, Tottori University, Tottori, Japan

 

13.   Angiotensin II alters the expression of duodenal iron transporters, hepatic hepcidin, and body iron distribution in mice.

Eur J Nutr. 54:709-719.(2015)

Soichiro Tajima1, 2, Yasumasa Ikeda1, Hideaki Enomoto1, 3, Mizuki Imao4, Yuya Horinouchi1, Yuki Izawa-Ishizawa1, Yoshitaka Kihira1, Rihito Miyamoto4, Keisuke Ishizawa4, Koichiro Tsuchiya4 and Toshiaki Tamaki1 

1Department of Pharmacology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan

2Department of Pharmacy, Kyushu University Hospital, Fukuoka, Japan

3Student Lab, Faculty of Medicine, University of Tokushima, Tokushima, Japan

4Department of Medical Pharmacology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan

  

14. Identification of Polyethylene Glycol-Resistant Macrophages on Stealth Imaging in Vitro Using Fluorescent Organosilica Nanoparticles

ACS nano. 2015 Jan 28.

Michihiro Nakamura*†, Koichiro Hayashi†, Mutsuki Nakano†‡, TakafumiKanadani†‡, Kazue Miyamoto†‡, Toshinari Kori, Kazuki Horikawa§
†Department of Anatomy and Cell Biology, The University of Tokushima Graduate School of Medical Sciences, 3-18-15 Kuramoto, Tokushima 770-8503, Japan

‡Student Lab, The University of Tokushima Faculty of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan
Tokushima Prefectural Industrial Technology Center, 11–2 Nishibari, >Saigacho, Tokushima 770–8021, Japan

§Division of Bioimaging, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan

 

15. A FRMD7 variant in a Japanese family causes congenital nystagmus.

Hum Genome Variation 2015;2:15002_1-4 doi:10.1038/hgv.2015.2

Kohmoto T1), Okamoto N, Satomura S, Naruto T, Komori T, Hashimoto T, Imoto I*2)

1) Student Lab, The University of Tokushima Faculty of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan

2) Department of Human Genetics, Institute of Health Biosciences, University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan

 

16. A novel PTCH1 mutation in a patient with Gorlin syndrome.

Hum Genome Variation 2014;114022_1-3 doi:10.1038/hgv.2014.22

Okamoto N, Naruto T, Kohmoto T1), Komori T, Imoto I*2)

1) Student Lab, The University of Tokushima Faculty of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan

2) Department of Human Genetics, Institute of Health Biosciences, University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan

 

17. Endothelial Nitric Oxide Synthase-Independent Pleiotropic Effects of Pitavastatin Against Atherogenesis and Limb Ischemia in Mice.

J Atheroscler Thromb. 2017 Jun 6. doi: 10.5551/jat.37747. [Epub ahead of print]

Mitsuhashi T1), Uemoto R2), Ishikawa K3), Yoshida S4), Ikeda Y5), Yagi S6), Matsumoto T7), Akaike M3), Aihara KI.2)

1) Student Laboratory, Faculty of Medicine, Tokushima University.

2) Department of Community Medicine for Diabetes and Metabolic Disorders, Tokushima University.

3) Department of Medical Education, Tokushima University.

4) Department of Hematology, Endocrinology & Metabolism, Tokushima University.

5) Department of Pharmacology, Tokushima University.

6) Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences.

7) Fujii Memorial Institute of Medical Sciences, Tokushima University.

 

18. Essential role of CCL21 in establishment of central selftolerance in T cells.

J Exp Med. 2017 Jun 13. pii: jem.20161864. doi: 10.1084/jem.20161864. [Epub ahead of print]

Mina Kozai,1 Yuki Kubo,1,2 Tomoya Katakai,4 Hiroyuki Kondo,1 Hiroshi Kiyonari,5 Karin Schaeuble,Sanjiv A. Luther,6 Naozumi Ishimaru,3 Izumi Ohigashi,1 and Yousuke Takahama1

1) Division of Experimental Immunology, Institute of Advanced Medical Sciences, Tokushima University.

2) Student Laboratory, Faculty of Medicine, Tokushima University.

3) Division of Molecular Pathology, Graduate School of Oral Sciences, Tokushima University.

4) Department of Immunology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan

5) Animal Resource Development Unit and Genetic Engineering Team, Institute of Physical and Chemical Research Center for Life Science Technologies, Kobe, Japan

6) Department of Biochemistry, Center for Immunity and Infection, University of Lausanne, Lausanne, Switzerland

 

19. Iron suppresses erythropoietin expression via oxidative stress-dependent hypoxia-inducible factor-2 alpha inactivation..

Lab Invest. 2017 May;97(5):555-566. doi: 10.1038/labinvest.2017.11.

Oshima K1,2, Ikeda Y1, Horinouchi Y1, Watanabe H3, Hamano H1,4, Kihira Y1,5, Kishi S6, Izawa-Ishizawa Y1, Miyamoto L7, Hirayama T8, Nagasawa H8, Ishizawa K3,4, Tsuchiya K7, Tamaki T1.

1) Department of Pharmacology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

2) Student Lab, Tokushima University Faculty of Medicine, Tokushima, Japan.

3) Department of Clinical Pharmacy, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

4) Department of Pharmacy, Tokushima University Hospital, Tokushima, Japan.

5) Department of Clinical Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan.

6) Department of Nephrology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

7) Department of Medical Pharmacology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

8) Laboratory of Pharmaceutical and Medicinal Chemistry, Gifu Pharmaceutical University, Gifu, Japan.

 

20. Prions Amplify through Degradation of the VPS10P Sorting Receptor Sortilin.

PLOS Pathogen, 2017

Keiji Uchiyama1,*, Mitsuru Tomita1,2, Masashi Yano1, Junji Chida1, Hideyuki Hara1, Nandita Rani Das1, Anders Nykjaer3 & Suehiro Sakaguchi1,*

1 Division of Molecular Neurobiology, Institute for Enzyme Research (KOSOKEN), Tokushima University, 3-18-15 Kuramoto, Tokushima 770-8503, Japan

2 Student Laboratory, Faculty of Medicine, Tokushima University, 3-18-15 Kuramoto, Tokushima 770-8503, Japan

3 Department of Biomedicine, Aarhus University, Aarhus, Denmark

 

21. Prion Protein Devoid of the Octapeptide Repeat Region Delays BSE Pathogenesis in Mice.

Journal of Virology, 2017(in press)

Hideyuki Hara,a,* Hironori Miyata,b,* Nandita Rani Das,a,* Junji Chida,a Tatenobu Yoshimochi,a,c Keiji Uchiyama,a Hitomi Watanabe,d Gen Kondoh,d Takashi Yokoyama,e Suehiro Sakaguchia#

aDivision of Molecular Neurobiology, The Institute for Enzyme Research (KOSOKEN), Tokushima University, Kuramoto, Tokushima, Japan

bAnimal Research Center, School of Medicine, University of Occupational and Environmental Health, Yahatanishi, Kitakyushu, Japan

cStudent Laboratory, Faculty of Medicine, Tokushima University, Kuramoto, Tokushima, Japan

dLaboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

eNational Institute of Animal Health (NIAH), National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki, Japan.

 

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