【掲載論文】

1. Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model.
    Youichi Sato, Atsushi Tajima, Motoki Katsurayama, Shiari Nozawa, Miki Yoshiike, Eitetsue Koh, Jiro Kanaya,
    Taro Shimizu, Amr S. Abu Lila, Miho Nishino, Yusuke Doi, Hidenori Ando, Masami Ukawa, Yu Ishima, Tatsuhiro Ishida
    Cancer Sci., 2017,[DOI:10.1111/cas.13305]
 
2. A replication study of a candidate locus for follicle-stimulating hormone levels and association analysis for semen quality
    traits in Japanese men
    Youichi Sato, Atsushi Tajima, Motoki Katsurayama, Shiari Nozawa, Miki Yoshiike, Eitetsue Koh, Jiro Kanaya,
    Mikio Namiki, Kiyomi Matsumiya, Akira Tsujimura, Kiyoshi Komatsu, Naoki Itoh, Jiro Eguchi, Issei Imoto, Aiko Yamauchi
    and Teruaki Iwamoto
    Journal of Human Genetics, 2016, [DOI: 10.1038/jhg.2016.82]
 
3. 2015年冬季の徳島市における水溶性酸性ガス及びPM2.5に含まれる陰イオンのオンライン分析
  富安 直弥、並川 誠、田中 秀治、竹内 政樹
    BUNSEKI KAGAKU, Vol.65, No.8, pp.425-432 (2016)
 
4. Cellular Interaction and Cytotoxicity of the Iowa Mutation of Apolipoprotein A-I(ApoA-IIowa) Amyloid Mediated
    by Sulfate Moieties of Heparan Sulfate
    Kaori Kuwabara, Kazuchika Nishitsuji, Kenji Uchimura, Shang-Cheng Hung, Makoto Mizuguchi, Hiroyuki Nakajima,
    Shiho Mikawa, Norihiro Kobayashi, Hiroyuki Saito, and Naomi Sakashita
    J. Biol. Chem. in Press, 2015, [DOI: 10.1074/jbc.M115.652545 jbc.M115.652545]

 

 

5. Gene silencing using 4’-thioDNA as an artificial template to synthesize short-hairpin RNA without inducing

    a detectable innate immune response

    Noriko Tarashima, Hidenori Ando, Takamitsu Kojima, Nozomi Kinjyo, Yosuke Hashimoto, Kazuhiro Furukawa,

    Tatsuhiro Ishida, and Noriaki Minakawa*

    Mol. Ther. –Nucl. Acids 2015, in press[DOI:10.1038/mtna.2015.48]

 

 

6. Advanced therapeutic approach for the treatment of malignant pleural mesothelioma via the intrapleural

    administration of liposomal pemetrexed.

    Ando, H., Kobayashi, S., Abu Lila A.S., Essam Eldin N., Kato, C., Shimizu, T., Ukawa, M., Kawazoe, K., Ishida, T.

    J. Control. Release 2015,29-36  [DOI: 10.1016/j.jconrel.2015.10.019]

 

 

7. Encapsulation in a rapid-release liposomal formulation enhances the anti-tumor efficacy of pemetrexed in

    a murine solid mesothelioma-xenograft model.

    Essam Eldin, N., Abu Lila, A.S., Kawazoe, K., Elnahas, H.M., Mahdy, M.A., Ishida, T.,

    Eur. J. Pharm. Sci., 2015,in press [DOI: 10.1016/j.ejps.2015.09.015.]

 
 
8. Amyloidogenic Mutation Promotes Fibril Formation of the N-terminal Apolipoprotein A-I on Lipid Membranes
   Chiharu Mizuguchi, Fuka Ogata, Shiho Mikawa, Kohei Tsuji, Teruhiko Baba, Akira Shigenaga,
   Toshinori Shimanouchi, Keiichiro Okuhira, Akira Otaka, and Hiroyuki Saito
   J. Biol. Chem. in Press, 2015, [DOI:10.1074/jbc.M115.664227]
 
 

9. Anti-PEG IgM and complement system are required for the association of second doses of PEGylated liposomes

    with splenic marginal zone B cells

    Taro Shimizu, Yu Mima, Yosuke Hashimoto, Masami Ukawa, Hidenori Ando, Hiroshi Kiwada, Tatsuhiro Ishida

    Immunobiology. 2015, 220, 1151–1160[DOI:10.1016/j.imbio.2015.06.005]

 
 
10. Anti-PEG IgM Is a Major Contributor to the Accelerated Blood Clearance of Polyethylene Glycol-Conjugated Protein
  Yu Mima, Yosuke Hashimoto, Taro Shimizu, Hiroshi Kiwada, and Tatsuhiro Ishida*

    Mol. Pharmaceutics.2015,12,2429−2435 [DOI:10.1021/acs.molpharmaceut.5b00144]

 
 
11. Faithful PCR Amplification of an Unnatural Base-Pair Analogue with Four Hydrogen Bond
   Noriko Tarashima,Yasuo Komatsu,Kazuhiro Furukawa,and Noriaki Minakawa*
   Chem.Eur.J.2015,21,10688-10695  [DOI: 10.1002/chem.201583062.]

 

 

12. Synthesis of DNA fragments containing 2’-deoxy-4’-selenonucleoside units using DNA polymerases:

   comparison of dNTPs with O, S and Se at the 4’-position in replication

     Noriko Tarashima, Tatsuya  Sumitomo, Hidenori Ando, Kazuhiro Furukawa, Tatsuhiro Ishida and Noriaki Minakawa*

     Org.Biomol.Chem.2015,13,6949-6952  [DOI: 10.1039/c5ob00941c ]

 

 

13. Molecular Complex Composed of β‑Cyclodextrin-Grafted Chitosan and pH-Sensitive Amphipathic

   Peptide for Enhancing Cellular Cholesterol Efflux under Acidic pH

     Yuki Takechi-Haraya,Kento Tanaka,Kohei Tsuji,Yasuo Asami, Hironori Izawa,Akira Shigenaga,Akira Otaka, Hiroyuki Saito, and Kohsaku Kawakami

     Bioconjugate Chem. 2015, 26, 572−581 [DOI:10.1021/acs.bioconjchem.5b00037]

 

 

14. Kinetic and Thermodynamic Analyses of Spontaneous Exchange between High-Density Lipoprotein-Bound and

   Lipid-Free Apolipoprotein A‑I

     Daisuke Handa, Hitoshi Kimura, Tatsuya Oka, Yuki Takechi, Keiichiro Okuhira, Michael C. Phillips,

     and Hiroyuki Saito

     Biochemistry.2015, 54, 1123−1131 [DOI: 10.1021/bi501345j]

 

 

15. Liposomal Pemetrexed: Formulation, Characterization and in Vitro Cytotoxicity Studies for Effective Management of

   Malignant Pleural Mesothelioma

     Noha Essam Eldin,Hanan Mohamed Elnahas, Mahmoud Abd-Elghany Mahdy, and Tatsuhiro Ishida

     Biol. Pharm. Bull..2015, 38, 461–469  [DOI:10.1248/bpb.b14-00769]

 

16. Analysis of Molecular Species Profiles of Ceramide-1-phosphate and Sphingomyelin Using MALDI-TOF Mass Spectrometry

   Ryouhei  YamashitaYumika TabataErina Iga,Michiyasu Nakao, Shigeki Sano,               

   Kentaro Kogure, Akira Tokumura, Tamotsu Tanaka

     Lipids,51,263-270,2016,

 

17. Nafion Membrane Tube-Based On-Line Concentrator. Application to Urinary Orotic Acid Determined by
     Suppressed Ion Chromatography
   Masaki Takeuchi, Naoyuki Miki, Kiichi Ishimine, and Hideji Tanaka
   J. Flow Injection Anal., 32,2, 97-100, 2015,JFIA(Journal of Flow Injection Analysis) Selection Award