【掲載論文】

2018年

 
Unnatural base pairs for synthetic biology.
Saito-Tarashima N., Minakawa N.
Chem. Pharm. Bull. 2018,66, 132–138 [DOI:10.1248/cpb.c17-00685]

 

Lysophosphatidic acid in medicinal herbs protects against indomethacin-induced gastric cell damage in vivo and in vitro.
Afroz S., Yagi A., Fujikawa K., Rahman M., Morito K., Fukuta T., Watanabe S., Kiyokage E., Toida K., Shimizu T., Ishida T., Kogure K., Tokumura A., Tanaka T.,
Prostaglandins & Other Lipid Mediators, 2018,in press [DOI:10.1016/j.prostaglandins.2018.01.003]

 

Intratumoral visualization of oxaliplatin within a liposomal formulation using X-ray fluorescence spectrometry.

Ando H., Abu Lila A.S., Tanaka M., Doi Y., Terada Y., Yagi N., Shimizu T., Okuhira K., Ishima Y., Ishida T.,
Mol. Pharm., 2018,15, 403-409 [DOI:10.1021/acs.molpharmaceut.7b00762]

 

 Reactivity of IgM antibodies elicited by PEGylated liposomes or PEGylated lipoplexes against auto and foreign antigens.

Ando H., Abu Lila A.S., Kawanishi M., Shimizu T., Okuhira K., Ishima Y., Ishida T.,
J.Control. Release, 2018,270, 114-119 [DOI:10.1016/j.jconrel.2017.12.002]

 

A Novel S-Sulfhydrated Human Serum Albumin Preparation Suppresses Melanin Synthesis,

Ikeda M., Ishima Y., Kinoshita R., Chuang V., Tasaka N., Matsuo N., Watanabe H., Shimizu T., Ishida T., Otagiri M., Maruyama T.,
Redox Biology, 2018,14, 354-360[DOI:10.1016/j.redox.2017.10.007]

 

2017年

 
Synthesis of 4’-selenoribonucleosides, the building blocks of 4’-selenoRNA, using a hypervalent iodine.
Saito-Tarashima N., Ota M., Minakawa N.
Curr. Protoc. Nucleic Acid Chem. 2017, 70, 1–21 [DOI:10.1002/cpnc.34]
 
Synthesis and evaluation of c-di-4’-thioAMP as an artificial ligand for c-di-AMP riboswitch.
Shiraishi K., Saito-Tarashima N., Igata Y., Murakami K., Okamoto Y., Miyake Y., Furukawa K., Minakawa N.
Bioorg. Med. Chem. 2017,25, 3883–3889  [DOI:10.1016/j.bmc.2017.05.042]
 
A ‘catch and release’ strategy towards HPLC-free purification of synthetic oligonucleotides using a phosphoramidite unit possessing a photocleavable azide linker. Igata
Y., Saito-Tarashima N., Matsumoto D., Sagara K., Minakawa N.
Bioorg. Med. Chem. 2017,25, 5962–5967 [DOI:10.1016/j.bmc.2017.09.014]
 
Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model.
Shimizu T., Abu Lila A.S., Nishio M., Doi Y., Ando H., Ukawa M., Ishima Y., Ishida T.,
Cancer. Sci., 2017,108, 1864-1869 [ DOI: 10.1111/cas.13305]
 
Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules.
Okuhira K, Shoda T, Omura R, Ohoka N, Hattori T,Shibata N, Demizu Y,Sugihara R, Ichino A, Kawahara H,Itoh Y, Ishikawa M, Hashimoto Y, Kurihara M, Itoh S,Saito H, Naito M,
Mol Pharmacol,2017,91,159–166 [DOI:10.1124/mol.116.105569]
 
Association of TUSC1 and DPF3 gene polymorphisms with male infertility.
Sato Y.,Hasegawa C.,Tajima A.,Nozawa S.,Miki Y.,Eitetsue K.,Kanaya J.,Namiki M.,Matsumiya K.,Tsujimura A.,Komatsu K.,Itoh N.,Eguchi J.,Yamauchi A.,Iwamoto T.,
J.Assist.Reprod.Genet.2017,35,1-7 [DOI:10.1007/s10815-017-1052-x]
 
Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model.
Youichi Sato, Atsushi Tajima, Motoki Katsurayama, Shiari Nozawa, Miki Yoshiike, Eitetsue Koh, Jiro Kanaya,
Taro Shimizu, Amr S. Abu Lila, Miho Nishino, Yusuke Doi, Hidenori Ando, Masami Ukawa, Yu Ishima, Tatsuhiro Ishida
Cancer Sci., 2017,[DOI:10.1111/cas.13305]
 
 

2016年

 
A replication study of a candidate locus for follicle-stimulating hormone levels and association analysis for semen quality
traits in Japanese men
Youichi Sato, Atsushi Tajima, Motoki Katsurayama, Shiari Nozawa, Miki Yoshiike, Eitetsue Koh, Jiro Kanaya,
Mikio Namiki, Kiyomi Matsumiya, Akira Tsujimura, Kiyoshi Komatsu, Naoki Itoh, Jiro Eguchi, Issei Imoto, Aiko Yamauchi
and Teruaki Iwamoto
Journal of Human Genetics, 2016, [DOI: 10.1038/jhg.2016.82]
 
2015年冬季の徳島市における水溶性酸性ガス及びPM2.5に含まれる陰イオンのオンライン分析
富安 直弥、並川 誠、田中 秀治、竹内 政樹
BUNSEKI KAGAKU, 2016,Vol.65, No.8, 425-432
 
Gene silencing using 4’-thioDNA as an artificial template to synthesize short-hairpin RNA without inducing

a detectable innate immune response

Noriko Tarashima, Hidenori Ando, Takamitsu Kojima, Nozomi Kinjyo, Yosuke Hashimoto, Kazuhiro Furukawa,

Tatsuhiro Ishida, and Noriaki Minakawa*

 Mol. Ther. –Nucl. Acids,2016, 5, e274[DOI:10.1038/mtna.2015.48]

 

Encapsulation in a rapid-release liposomal formulation enhances the anti-tumor efficacy of pemetrexed in

a murine solid mesothelioma-xenograft model.

Essam Eldin, N., Abu Lila, A.S., Kawazoe, K., Elnahas, H.M., Mahdy, M.A., Ishida, T.,

Eur. J. Pharm. ,2016, 81, 60-66,[DOI: 10.1016/j.ejps.2015.09.015.]

 

Analysis of Molecular Species Profiles of Ceramide-1-phosphate and Sphingomyelin Using MALDI-TOF Mass Spectrometry

Ryouhei  YamashitaYumika TabataErina Iga,Michiyasu Nakao, Shigeki Sano,               

Kentaro Kogure, Akira Tokumura, Tamotsu Tanaka

 Lipids,51,263-270,2016,

 

2015年

 
Cellular Interaction and Cytotoxicity of the Iowa Mutation of Apolipoprotein A-I(ApoA-IIowa) Amyloid Mediated
 by Sulfate Moieties of Heparan Sulfate
 Kaori Kuwabara, Kazuchika Nishitsuji, Kenji Uchimura, Shang-Cheng Hung, Makoto Mizuguchi, Hiroyuki Nakajima,
 Shiho Mikawa, Norihiro Kobayashi, Hiroyuki Saito, and Naomi Sakashita
 J. Biol. Chem. 2015, 290, 24210-21, [DOI: 10.1074/jbc.M115.652545 jbc.M115.652545]

 

Advanced therapeutic approach for the treatment of malignant pleural mesothelioma via the intrapleural

administration of liposomal pemetrexed.

Ando, H., Kobayashi, S., Abu Lila A.S., Essam Eldin N., Kato, C., Shimizu, T., Ukawa, M., Kawazoe, K., Ishida, T.

J. Control. Release 2015,29-36  [DOI: 10.1016/j.jconrel.2015.10.019]

 
Amyloidogenic Mutation Promotes Fibril Formation of the N-terminal Apolipoprotein A-I on Lipid Membranes
Chiharu Mizuguchi, Fuka Ogata, Shiho Mikawa, Kohei Tsuji, Teruhiko Baba, Akira Shigenaga,
Toshinori Shimanouchi, Keiichiro Okuhira, Akira Otaka, and Hiroyuki Saito
J. Biol. Chem,2015, 290, 20947-20959. [DOI:10.1074/jbc.M115.664227]
 
 Anti-PEG IgM and complement system are required for the association of second doses of PEGylated liposomes

 with splenic marginal zone B cells

 Taro Shimizu, Yu Mima, Yosuke Hashimoto, Masami Ukawa, Hidenori Ando, Hiroshi Kiwada, Tatsuhiro Ishida

Immunobiology. 2015, 220, 1151–1160[DOI:10.1016/j.imbio.2015.06.005]

 
 Anti-PEG IgM Is a Major Contributor to the Accelerated Blood Clearance of Polyethylene Glycol-Conjugated Protein
Yu Mima, Yosuke Hashimoto, Taro Shimizu, Hiroshi Kiwada, and Tatsuhiro Ishida*

 Mol. Pharmaceutics.2015,12,2429−2435 [DOI:10.1021/acs.molpharmaceut.5b00144]

 
Faithful PCR Amplification of an Unnatural Base-Pair Analogue with Four Hydrogen Bond
 Noriko Tarashima,Yasuo Komatsu,Kazuhiro Furukawa,and Noriaki Minakawa*
 Chem.Eur.J.2015,21,10688-10695  [DOI: 10.1002/chem.201583062.]

 

 Synthesis of DNA fragments containing 2’-deoxy-4’-selenonucleoside units using DNA polymerases:

 comparison of dNTPs with O, S and Se at the 4’-position in replication

 Noriko Tarashima, Tatsuya  Sumitomo, Hidenori Ando, Kazuhiro Furukawa, Tatsuhiro Ishida and Noriaki Minakawa*

 Org.Biomol.Chem.2015,13,6949-6952  [DOI: 10.1039/c5ob00941c ]

 

Molecular Complex Composed of β‑Cyclodextrin-Grafted Chitosan and pH-Sensitive Amphipathic

Peptide for Enhancing Cellular Cholesterol Efflux under Acidic pH

Yuki Takechi-Haraya,Kento Tanaka,Kohei Tsuji,Yasuo Asami, Hironori Izawa,Akira Shigenaga,Akira Otaka, Hiroyuki Saito, and Kohsaku Kawakami

Bioconjugate Chem. 2015, 26, 572−581 [DOI:10.1021/acs.bioconjchem.5b00037]

 

Kinetic and Thermodynamic Analyses of Spontaneous Exchange between High-Density Lipoprotein-Bound and

Lipid-Free Apolipoprotein A‑I

Daisuke Handa, Hitoshi Kimura, Tatsuya Oka, Yuki Takechi, Keiichiro Okuhira, Michael C. Phillips,

 and Hiroyuki Saito

Biochemistry.2015, 54, 1123−1131 [DOI: 10.1021/bi501345j]

 

 

Liposomal Pemetrexed: Formulation, Characterization and in Vitro Cytotoxicity Studies for Effective Management of

Malignant Pleural Mesothelioma

Noha Essam Eldin,Hanan Mohamed Elnahas, Mahmoud Abd-Elghany Mahdy, and Tatsuhiro Ishida

 Biol. Pharm. Bull..2015, 38, 461–469  [DOI:10.1248/bpb.b14-00769]

 

 

 Nafion Membrane Tube-Based On-Line Concentrator. Application to Urinary Orotic Acid Determined by
 Suppressed Ion Chromatography
Masaki Takeuchi, Naoyuki Miki, Kiichi Ishimine, and Hideji Tanaka
J. Flow Injection Anal., 32,2, 97-100, 2015,JFIA(Journal of Flow Injection Analysis) Selection Award