最近の業績

2011年10月13日

2009年(平成21年)

1)Keisuke Ishizawa, Kunihisa Yamaguchi, Yuya Horinouchi, Yayoi Fukuhara, Soichiro Tajima, Shuichi Hamano, Shuhei Tomita, Koichiro Tsuchiya, Toshiaki Tamaki

Drug Discovery for Overcoming Chronic Kidney Disease (CKD):

Development of Drugs on Endothelial Cell Protection for Overcoming CKD

Journal of Pharmacological Sciences 109, 14-19, 2009

 

2) Ishizawa K, Izawa-Ishizawa Y, Ohnishi S, Motobayashi Y, Kawazoe K, Hamano S, Tsuchiya K, Tomita S, Minakuchi K, Tamaki T.

Quercetin glucuronide inhibits cell migration and proliferation by platelet-derived growth factor in vascular smooth muscle cells

Journal of Pharmacologycal Sceinces 109, 257-264, 2009

 

3) 曽根三郎,玉置俊晃,村澤普恵

臨床研究における利益相反マネージメント

臨床薬理 Jpn IJ clin Pharmacol Ther 40(3), 87-91, 2009

 

4) Yuki Motobayashi, Yuki Izawa-Ishizawa, Keisuke Ishizawa, Sakiko Orino, Kunihisa Yamaguchi, Kazuyoshi Kawazoe, Shuichi Hamano, Koichiro Tsuchiya, Shuhei Tomita and Toshiaki Tamaki

Adiponectin inhibits insulin-like growth factor-1-induced cell migration by the suppression of extracellular signal-regulated kinase 1/2 activation, but not Akt in vascular smooth muscle cells

Hypertens Res 32:188-193, 2009

 

5) Keisuke Ishizawa, Narantungalag Dorjsuren, Yuki Izawa-Ishizawa, Rika Sugimoto, Yasumasa Ikeda, Yoshitaka Kihira, Kazuyoshi Kawazoe, Shuhei Tomita, Koichiro Tsuchiya, Kazuo Minakuchi and Toshiaki Tamaki

Inhibitory effects of adiponectin on platelet-derived growth factor-induced mesangial cell migration

Journal of Endocrinology 202,309-316, 2009 

 

2010年(平成22年)

 

1) Hirotsugu Kurobe, Masahisa Urata, Masaki Ueno, Masaaki Ueki, Shiro Ono, Yuki Izawa-Ishizawa, Yayoi Fukuhara, Yu Lei, Adiratna Mat Ripen, Tamotsu Kanbara, Ken-ichi Aihara, Keisuke Ishizawa, Masashi Akaike, Frank J Gonzalez, Toshiaki Tamaki, Yousuke Takahama, Masanori Yoshizumi, Tetsuya Kitagawa, Shuhei Tomita

Role of Hif-1α in T cells as a negative regulator in development of vascular remodeling"

Arteriosclerosis, Thrombosis and Vascular Biology 30(2):210-7, 2010

 

2) S. Tajima, K. Tsuchiya, Y. Horinouchi, K. Ishizawa, K. Teraoka, S. Tomita, K. Kawazoe, H. Houchi, T.Tamaki, K. Minakuchi

Effect of angioyensin receptor blocker on induction of iron metabolism of HGECs by transferrin

 

3) Urushihara M, Takamatsu M, Shimizu M, Kondo S, Kinoshita Y, Suga K, Kitamura A, Matsuura S, Yoshizumi M, Tamaki T, Kawachi H, Kagami S.

ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis

Am J Physiol Renal Physiol 298(1):F167-76, 2010

 

4) Ishizawa K, Izawa-Ishizawa Y, Dorjsuren N, Miki E, Kihira Y, Ikeda Y, Hamano S, Kawazoe K, Minakuchi K, Tomita S, Tsuchiya K, Tamaki T.

Angiotensin II receptor blocker attenuates PDGF-induced mesangial cell migration in a receptor-independent manner

Nephrol Dial Transplant 25(2):364-72, 2010

 

5) Tsuchiya K, Tomita S, Ishizawa K, Abe S, Ikeda Y, Kihira Y, Tamaki T.

Dietary nitrite ameliorates renal injury in L-NAME-induced hypertensive rats

Nitric Oxide 15;22(2):98-103, 2010 Review

 

6) Kurobe H, Urata M, Ueno M, Ueki M, Ono S, Izawa-Ishizawa Y, Fukuhara Y, Lei Y, Ripen AM, Kanbara T, Aihara K, Ishizawa K, Akaike M, Gonzalez FJ, Tamaki T, Takahama Y, Yoshizumi M, Kitagawa T, Tomita S.

Role of hypoxia-inducible factor 1alpha in T cells as a negative regulator in development of vascular remodeling

Arterioscler Thromb Vasc Biol 30(2):210-7, 2010

 

7) Liu G, Miyata K, Hitomi H, Yao L, Sun GP, Suzaki Y, Hosomi N, Kiyomoto H, Nakano D, Tamaki T, Yoshizumi M, Nishiyama A.

Involvement of mineralocorticoid receptor in high glucose-induced big mitogen-activated protein kinase 1 activation and mesangial cell proliferation

J Hypertens 28(3):536-42, 2010

 

8) Tajima S, Tsuchiya K, Horinouchi Y, Ishizawa K, Ikeda Y, Kihira Y, Shono M, Kawazoe K, Tomita S, Tamaki T.

Effect of angiotensin II on iron-transporting protein expression and subsequent intracellular labile iron concentration in human glomerular endothelial cells

Hypertens Res 33(7):713-21, 2010

 

9) Ikeda Y, Aihara K, Akaike M, Sato T, Ishikawa K, Ise T, Yagi S, Iwase T, Ueda Y, Yoshida S, Azuma H, Walsh K, Tamaki T, Kato S, Matsumoto T.

Androgen receptor counteracts Doxorubicin-induced cardiotoxicity in male mice

Mol Endocrinol 24(7):1338-48, 2010

 

2011年(平成23年)

 

1) Ikeda Y, Tajima S, Yoshida S, Yamano N, Kihira Y, Ishizawa K, Aihara KI, Tomita S, Tsuchiya K, Tamaki T.

Deferoxamine promotes angiogenesis via the activation of vascular endothelial cell function

Atherosclerosis 21, 2011

 

2) Shimohata T, Nakano M, Lian X, Shigeyama T, Iba H, Hamamoto A, Yoshida M, Harada N, Yamamoto H, Yamato M, Mawatari K, Tamaki T, Nakaya Y, Takahashi A.

Vibrio parahaemolyticus infection induces modulation of IL-8 secretion through dual pathway via VP1680 in Caco-2 cells

J Infect Dis 203(4):537-44, 2011

 

3) Horinouchi Y, Tsuchiya K, Taoka C, Tajima S, Kihira Y, Matsuda Y, Shishido K, Yoshida M, Hamano S, Kawazoe K, Ikeda Y, Ishizawa K, Tomita S, Tamaki T.

Antioxidant effects of photodegradation product of nifedipine

Chem Pharm Bull (Tokyo) 59(2):208-14, 2011

 

4) Fukuhara Y, Tsuchiya K, Horinouchi Y, Tajima S, Kihira Y, Hamano S, Kawazoe K, Ikeda Y, Ishizawa K, Tomita S, Tamaki T.

Protective effect of photodegradation product of nifedipine against tumor necrosis factor alpha-induced oxidative stress in human glomerular endothelial cells

J Med Invest 58(1-2):118-26, 2011

 

5) Tomita S, Kihira Y, Imanishi M, Fukuhara Y, Imamura Y, Ishizawa K, Ikeda Y, Tsuchiya K, Tamaki T.

Pathophysiological Response to Hypoxia - From the Molecular Mechanisms of Malady to Drug Discovery:Inflammatory Responses of Hypoxia-Inducible Factor 1α (HIF-1α) in T Cells Observed in Development of Vascular Remodeling

J Pharmacol Sci Mar 16, 2011

 

6) Ishizawa K, Yoshizumi M, Kawai Y, Terao J, Kihira Y, Ikeda Y, Tomita S, Minakuchi K, Tsuchiya K, Tamaki T.

Pharmacology in Health Food:Metabolism of Quercetin In Vivo and Its Protective Effect Against Arteriosclerosis

J Pharmacol Sci Mar 24, 2011

 

7) 池田康将,田島壮一郎,山野範子,土屋浩一郎,玉置俊晃

循環器疾患と糖尿病における生体内鉄の意義

血管 34:75-85, 2011