業績 1999-2008

2011年10月13日

1999年(平成11年)

1) Kyoji Morita, Itsuo Tokunaga, Shin-ich Kubo

Cytotoxic effect of paraquat on rat C6 glioma cells:Evidence for the possibility of non-oxidative damage to the cells

Jpn. J. Pharmacol. 79:121-124, 1999

 

2) 玉置俊晃,吉栖正典

総説 微小循環 腎微小循環

日本薬理学雑誌 113:261-267, 1999

 

3) Kyoji Morita, Kazunori Ishimura, Yoshihiro Tsuruo, Dona L. Wong

Dexamethasone enhances serum deprivation-induced necrotic death of rat C6 glioma cells through activation of glucocorticoid receptors

Brain Res. 816:309-316, 1999

 

4) Yuichi Ozawa, Masanori Yoshizumi, Daisuke Inui, Koichiro Tsuchiya, Hitoshi Houchi, Toshiaki Tamaki, Kazuo Minakuchi

Plasma levels of free and sulfoconjugated catecholamines in patients with atherosclerosis

Biol. Pharm. Bull. 22:657-659, 1999

 

5) Hitoshi Houchi, Mami Azuma, Masanori Yoshizumi, Toshiaki Tamaki, and Kazuo Minakuchi

Possible role of bradykinin on stimulus-secretion coupling in adrenal chromaffin cells

J. Med. Invest. 46:1-9, 1999

 

6) 乾大資,桐間一嘉,小澤祐一,須崎友紀,長谷川豊司,土屋浩一郎,吉栖正典,玉置俊晃

単離ウサギ輸入及び輸出細動脈におけるアデノシン受容体

四国医学雑誌 55:124-130, 1999

 

7) Daisuke Inui, Masanori Yoshizumi, Naoko Okishima, Hitoshi Houchi, Koichiro Tsuchiya, Hiroshi Kido, and Toshiaki Tamaki

Mechanism of endothelin-1-(1-31)-induced calcium signaling in human coronary artery smooth muscle cells

Am. J. Physiol. 276:E1067-E1072, 1999

 

8) Hiroaki Yasuoka, Masayoshi Yoshizumi, Daisuke Inui, Naoko Okishima, Hitoshi Houchi, Kazuyoshi Kirima, Syuzo Oshita, Hiroshi Kido and Toshiaki Tamaki

Effect of endothelin-1 (1-31) on intracellular free calcium in cultured human mesangial cells

Life Science 65:PL267-272, 1999

 

9) 玉置俊晃,吉栖正典

疾患と臨床薬理 “腎・泌尿器疾患と治療薬”

医薬ジャーナル社 1999年8月10日発行

 

10) 土屋浩一郎,豊田佳代子

疾患と臨床薬理 “薬物の血中濃度測定法(TDM)”

医薬ジャーナル社 1999年8月10日発行

 

11) Koichiro Tsuchiya, Jin-Jie Jiang, Masanori Yoshizumi, Toshiaki Tamaki, Hitoshi Houchi, Kazuo Minakuchi, Kenji Fukuzawa, Ronald P. Mason

Nitric oxide-forming reactions of the water-soluble nitric oxide spin-trapping agent, MGD

Free Rad. Biol. Med. 27:347-355, 1999

 

12) Masanori Yoshizumi, Daisuke Inui, Kazuyoshi Kirima, Koichiro Tsuchiya, Hitoshi Houchi, Mani Azuma, Hiroaki Yasuoka, Hiroshi Kido and Toshiaki Tamaki

Comparison of the effects of endothelin-1,-2 and -3(1-31) on changes in [Ca2+]i in human coronary artery smooth muscle cells

Jpn. J. Pharmacol. 81:298-304, 1999

 

13) Takabumi Umeda, Mami Azuma, Hitoshi Houchi, Toshitaka Ikehara, Fumiaki Shono, Masanori Yoshizumi, Toshiaki Tamaki, Kazuo Minakuchi

Stimulatory effect of enkephalines on calcium efflux from bovine adrenal chromaffin cells in culture

Life Science 65:PL247-252, 1999

 

14) Yuichi Ozawa, Masanori Yoshizumi, Yasushi Fukuta, Daisuke Inui, Koichiro Tsuchiya, Hitoshi Houchi,Toshiaki Tamaki, Kazuo Minakuchi

Dopamine Clearance During dopamine infusion in infants and children after cardiac surgery

Cardiovasc. Pharmacol. 34(4):S85-S89, 1999

 

15) Ogawa Y, Yoshizumi M, Kitagawa T, Kitaichi T, Katoh I, Hisaeda H, Himeno K.

Investigation of the mechanism of lymphocyte injection therapy in treatment of lymphedema with special emphasis on cell adhesion molecule (L-selectin)

Lymphology 32(4):151-156, 1999

 

16) Prem K. Samuel, Chang Xi Zhang, Masanori Yoshizumi, John M. Snider, William H. Risher, Bradford Berk, George L. Hicks, Tingchung Wang

Aprotinin pretreatment improves hypothermic cardiac preservation involving bradykinin receptors and protein kinase C

Surgical Forum II298-1-4, 1999

 

17) K. Morita, Y. Tsuruo, K. Ishimura, S. Her, RA. Bell, and DL. Wong

Influence of serum-free culture conditions on steroid 5a-reductase mRNA expression in rat C6 glioma cells

Brain Res. 816:179-182, 1999

 

18) S. Kubo, I. Tokunaga, A. Yamamoto, and K. Morita

Immunohistochemical studies on paraquat-induced gamage to neuronal and glial cells in rat hippocampus

Acta Histochem. Cytochem. 32:373-376, 1999

 

19) S. Kubo, I. Tokunaga, A. Yamamoto, T. Dotohda and K. Morita

Relevance of heat-shock protein 70 expression as a histological marker of paraquat-induced damage to rat liver cells

Acta Histochem. Cytochem. 32:381-386, 1999

 

20) Kazuhiro Mori, Yasunobu Hayabuchi, Yasuhiro Kuroda, Yutaka Nakaya, Koichiro Tsuchiya, Hideki Moritoki

Age-related endothelium-dependent vascular relaxation in rat thoracic aorta in response to colforsin

Pediatrics International 41:673-681, 1999

 

2000年(平成12年)

1) 玉置俊晃

高血圧 “腎微小循環”

日本臨床 58増刊号, 2000年1月31日発行

 

2) Tsuchiya K, Yoshizumi M, Houchi H, Mason RP.

Nitric Oxide-forming Reaction between the Iron-N-Methyl-D-glucamine Dithiocarbamate Complex and Nitrite

J Biol Chem. 275(3):1551-1556, 2000

 

3) Jun-ichi Abe, Masanori Okuda, Qunhua Huang, Masanori Yoshizumi, Bradford C. Berk

Reactive oxigen species activate p90 ribosomal S6 kinase via Fyn and Ras

J. Biol. Chem. 275:1739-1748, 2000

 

4) M.Yoshizumi, J. Abe, J. Haendeler, Q. Huang and BC. Berk

Src and Cas mediate JNK activation but not ERK1/2 and p38 kinasea by reactive oxygen species

J Biol Chem. 275:11706-11712, 2000

 

5) 安部陽一,岩尾洋,三浦克之,玉置俊晃

新生理科学大系(19)腎および体液調節の生理学

医学書院 第3編腎生理学各論 第1章腎機能の基本過程 I腎循環 2000年3月1日発行

 

6) 小澤祐一,寺岡和彦,芳地一,東満美,吉栖正典,玉置俊晃,水口和生

強心配糖体の培養ウシ副腎クロマフィン細胞におけるカテコールアミン生合成に対する影響

臨床薬理 31:251-252, 2000

 

7) M. Yoshizumi, S. Kagami, Y. Suzaki, K. Tsuchiya, H. Houchi, T. Hisayama, H. Fukui, T.Tamaki

Effect of endothelin-1(1-31) on the human mesangial cell proliferation

The Japanese Journal of Pharmacology 84(2):146-155, 2000

 

8) D. Inui, M. Yoshizumi, Y. Suzaki, K. Kirima, K. Tuchiya, H. Houchi, S. Kagami, and T. Tamaki

Effect of endothelin-1(1-31) on p38 mitogen-activated protein kinase in cultured human mesangial cells

Life Science 68:635-645, 2000

 

9) 吉栖正典,沖嶋直子,乾大資,土屋浩一郎,玉置俊晃

エンドセリン1(1-31)の腎作用

腎と透析 49:739-743, 2000

 

10) Yuichi Ozawa, Hitoshi Houchi, Kazuhiko Teraoka, Mami Azuma, Takahiro Kamimura, Masanori Yosizumi, Koichiro Tsuchiya, Toshiaki Tamaki, Kazuo Minakuchi

Long-term regulation of catecholamine formation by ouabain in cultured bovine adrenal cromaffin cells

J. Cardiovasc. Pharmacol. 36(2):S15-S18, 2000

 

11) T. Gotohda, I. Tokunaga, S. Kubo, K. Morita

Enhancement of glia cell line-derived ne urotrophic favtor expression in rat adrenal glands by toluene exposure

Horm. Metab. Res. 32:301-305, 2000

 

12) T. Gotohda, K. Kuwada, K. Morita, S. Kubo, I. Tokunaga

Elevation of steroid 5a-reductase mRNA levels in rat cerebellum by toluene inhalation: Possible relation to GFAP expression

J. Toxicol. Science 25:223-231, 2000

 

13) Erdem Yesilada, Koichiro Tsuchiya, Yoshihisa Takaishi, Kazuyoshi Kawazoe

Isolation and characterization of free radical scavenging flavonoid glycosides from the flowers of Spartium junceum by activity-guided fractionation

Journal of Ethnopharmacology 73:471-478, 2000

 

2001年(平成13年)

1) Naoko Okishima, Masanori Yoshizumi, Koichiro Tuchiya, Ping Cui, Hiroko Kitamura, Toshiaki Tamaki, Hiroshi Kido

Determination of the levels of novel 31-amino acid endothelins and endothelins in human lungs

Life Sciences 68:2073-2080, 2001

 

2) M. Yoshizumi, K. Tsuchiya and T. Tamaki

Signal transduction of reactive oxygen species and mitogen-activated protein kinases in cardiovascular disease

J. Med. Invest. 48:11-24, 2001

 

3) 玉置俊晃

教育・研修における臨床薬理学

大阪保険医雑誌 2001年2月号

 

4) Moe kyaw, M. Yoshizumi, K. Tsuchiya, K. Kirima and T. Tamaki

Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells

Hypertension Research 24:251-261, 2001

 

5) K. Kirima, K. Tsuchiya, M. Yoshizumi, T. Kameda, H. Houchi, N. Azuma, T. Tamaki

Electron paramagnetic resonance study on free radical scavanging and/or generating activity of dopamine-4-0-sulfate.

Chemical Pharmaceutical Bulletin 49:576-580, 2001

 

6) I. Rusyn, MB. Kadiiska, A. Dikalova, H. Kono, M. Yin, K. Tsuchiya, RP. Mason, JM. Peters, FJ. Gonzalez, BH. Segal, SM. Hollande, RG. Thurman

Phthalates rapidly increase production of reactive oxygen species in vivo: Role of Kupffer cells

Molecular Pharmacology 59:744-750, 2001

 

7) S. Kagami, K. Urushihara, S. Kondo, K. Loster, W. Reutter, T. Tamaki, M. Yoshizumi, Y. Kuroda

Requirement for tyrosine kinase-ERK1/2 signaling in a1b1 integrin-mediated collagen matrix remodeling by rat mesangial cells

Experimental Cell Research 268:274-283, 2001

 

8) Surapisitchat J, Hoefen RJ, Pi X, Yoshizumi M, Yan C, Berk BC

Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members

Proc Natl Acad Sci USA. 98(11):6476-81, 2001

 

9) Pig Cui, Kenji Tani, Hiroko Kitamura, Yuushi Okumura, Mihiro Yano, Daisuke Inui, Toshiaki Tamaki, Saburo Sone, Hiroshi Kido

A novel bioactive 31-amino acid endothelin-1 is a potent chemotactic peptide for human neutrophils and monocytes

J. Leukocyte Biology 70:306-312, 2001

 

10) T. Nakamura, H. Houchi, A. Minami, S. Sakamoto, K. Tsuchiya, Y. Niwa, K. Minakuchi, Y. Nakaya

Endothelium-dependent relaxation by cilostazol, a phosphodiesterase III inhibitor, on rat thoracic aorta.

Life Sciences 69:1709-1715, 2001

 

11) M. Yoshizumi, K. Tsuchiya, K. Kirima, Moe Kyaw, Y. Suzaki, T. Tamaki

Quercetin inhibits Shc- and Phosphatidylinositol 3-kinase-mediated c-Jun N-terminal kinase activation by angiotensin II in cultured rat aortic smooth muscle cells

Molecular Pharmacology 60:656-665, 2001

 

12) K. Ishizawa, M. Yoshizumi, K. Tsuchiya, E. Takishita, Y. Nakaya, K. Kishi, Y. Ebina, H. Houchi, K. Minakuchi, T. Tamaki.

Effects of losartan in combination with or without exercise on insulin resistance in OLETF rats

Eur. J. Pharmacol. 430:359-367, 2001

 

13) W. Che, J. Abe, M. Yoshizumi, Q. Huang, M. Glassman, S. Ohta, MG. Melaragno, V. Poppa, C. Yan, N. Lerner-Marmarosh, C. Zhang, Y. Wu, R. Arlinghaus, BC. Berk

p160 Bcr mediates platelet-derived growth factor activation of extracellular signal-regulated kinase in vascular smooth muscle cells

Circulation 104:1399-1406, 2001

 

14) Bradford C. Berk, James Surapisitchat, Masanori Yoshizumi, Chen Yan, Ryan Hoefen, and Jun-ichi Abe

Atheroprotective mechanisms of fluid shear stress: Nitric oxide independent inhibition of signal transduction mediated by inflammatory cytokines

Vascular Endothelium - Source and Target of inflammatory Mediators Edited by John D. Callow, Alan D. Callow, Una S. Ryan, Maya Simionescu

IOS Press, NATO Science Series, 2001

 

15) Yasuchika Takeishi, Qunhua Huang, Tingchung Wang, Michael Glassman, Masanori Yoshizumi, Wenyi Che, Nicole Lerner-Marmarosh, Changxi Zhang, Chen Yan, Shinsuke Ohta, Richard A. Walsh, Bradford C. Berk and Jun-ichi Abe

Srk family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: Modulation of MAP kinases activation by ischemic preconditioning

J. Mol Cell Cardiology 33:1989-2005, 2001

 

16) Masashi Kano, Yutaka Masuda, Takashi Tominaga, Takaki Horo, Takashi Kitaichi, Masanori Yoshizumi, Tetsuya Kitagawa

Collagen synthesis and collagenase activity of cryopreserved heart valves

J. Thoracic and Cardiovascular Surgery 122:706-711, 2001

 

17) Yasuchika Takeishi, Qunhua Huang, Tingchung Wang, Michael Glassman, Masanori Yoshizumi, Christopher P. Baines, Jiing-Dwan Lee, Hisaaki Kawakatsu, Wenyi Che, Nicole Lerner-Marmarosh, Changxi Zhang, Chen Yan, Shinsuke Ohta, Richard A. Walsh, Brdford C. Berk and Jun-ichi Abe

Src family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: Modulation of MAP kinases activation by ischemic preconditioning

J. Mol. Cell Cardiol. 33:1989-2005, 2001

 

18) Jun-ichi Abe, Wenyi Che, Masanori Yoshizumi, Qunhua Huang, Michael Glassman, Shinsuke Ohta, Y Wu, R. Arlinghaus, Brdford C. Berk

Bcr in vascular smooth muscle cells involvment of Ras and Raf-1 activation by Bcr

Ann. NY Acad Sci. 974:341-343, 2001

 

19) K. Morita, A. Kuwada, A. Sano, M. Samkata, H. Sei, Y. Morita

Semi-quantitative RT-PCR analysis of environmental influence on P450scc and PNMT mRNA expression in rat adrenal glands

Life Sciences 70:73-80, 2001

 

20) 吉栖正典

若手研究者による最新海外情報―1

心血管病における酸化ストレスの関与とMAP kinaseの役割

血管 24:181-185, 2001

 

2002年(平成14年)

1) Yuki Suzaki, Masanori Yoshizumi, Shoji Kagami, A. Hajime Koyama, Yutaka Taketani, Hitoshi Houchi, Koichiro Tsuchiya, Eiji Takeda and Toshiaki Tamaki

Hydrogen peroxide stimulates c-Src-mediated big mitogen-activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC12 cells: potential role in cell survival following oxidative insults

J. Biol. Chem. 277(11):9614-9621, 2002

 

2) Maki Urushihara, Shoji Kagami, Takashi Kuhara, Toshiaki Tamaki, Yasuhiro Kuroda

Glomerular distribution and gelatinolytic activity of natrix metalloproteinases in human glomerulonephritis.

Nephrology Dialysis Transplantation 17:1189-1196, 2002

 

3) 吉栖正典,石澤啓介,土屋浩一郎,玉置俊晃

インスリン抵抗性に対するロサルタンおよびロサルタンと運動の併用による効果

―モデルラットを用いたin vivoでの検討―

(財)明治生命厚生事業団第17回健康医科学研究助成論文集 2002年3月

 

4) Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Kazuyoshi Kirima, Yuki Suzaki, Shinji Abe, Toyoshi Hasegawa, Toshiaki Tamaki

Antioxidants inhibit endothelin-1(1-31)-induced proliferation of vascular smooth muscle cells via the inhibition of mitogen-activated protein (MAP) kinase and activator protein-1 (AP-1)

Biochemical Pharmacology 64:1521-1531, 2002

 

5) Akiko Kitamura, Shoji Kagami, Maki Urushihara, Syuji Kondo, Masanori Yoshizumi, Toshiaki Tamaki, and Yasuhiro Kuroda

Endothelin-1 is a potent stimulator of a1b1 integrin-mediated collagen matrix remodeling by rat mesangial cells.

Biochem. Biophys. Res. Commun. 299:555-561, 2002

 

6) Masanori Yoshizumi, Koichiro Tsuchiya, Yuki Suzaki, Kazuyoshi Kirima, Moe Kyaw, Jae-Hak Moon, Junji Terao and Toshiaki Tamaki

Quercetin Glucronide prevents VSMC hypertrophy by angiotensin II via the inhibition of JNK and AP-1 signaling pathway

Biochemical and Biophysical Research Communications 293:1458-1465, 2002

 

7) 土屋浩一郎,吉栖正典,玉置俊晃

亜硝酸と一酸化窒素(NO)

血管 25:63-71, 2002

 

8) Masanori Yoshizumi, Toshiaki Kogame, Yuki Suzaki, Yoshiko Fujita, Moe Kyaw, Kazuyoshi Kirima, Keisuke Ishizawa, Koichiro Tsuchiya, Shoji Kagami and Toshiaki Tamaki

Ebselen attenuates oxidative styress-induced apoptosis via the inhibition of the c jun N-terminal kinase and activator protein-1 signaling pathway in PC12 cells

Br. J. Pharmacology 136:1023-132, 2002

 

9) Koichiro Tsuchiya, Kazuyoshi Kirima, Masanori Yoshizumi, Hitoshi Houchi, Toshiaki Tamaki, Ronald P. Mason.

The role of thiol and nitrosothiol compounds in the nitric oxide-forming reactions of the iron-N-methyl-D-glucamine dithiocarbamate complex.

Biochemical Journal 367:771-779, 2002

 

10) D. Deliorman Orhan, E. Yesilada, F. Ergun, K. Tsuchiya, Y. Takaishi.

The antioxidant activity of the extracts and fractions from carduus nutans L.

J. Fac. Pharm. Gazi 19:61-66, 2002

 

11) Che W, Lerner-Marmarosh N, Huang Q, Osawa M, Ohta S, Yoshizumi M, Glassman M, Lee JD, Yan C, Berk BC, Abe J.

Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression

Circ Res. 90(11):1222-30, 2002

 

12) Huang Q, Lerner-Marmarosh N, Che W, Ohta S, Osawa M, Yoshizumi M, Glassman M, Yan C, Berk BC, Abe J.

The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation

J Biol Chem. 277(32):29330-41, 2002

 

2003年(平成15年)

1) Yuki Suzaki, Masanori Yoshizumi, Yukio Yamashita, Shinji Abe, Koichiro Tsuchiya, Yumiko Satoh,Yasuhiro Kuroda, Kazuya Horike, Masashi Kano, Yoshio Fukuta, Takasji Kitaichi, Takaki Hori, Yutaka Masuda, Tetsuya Kitawgawa, Kazuo Minakuchi, and Toshiaki Tamaki

Determination of plasma concentrations of endothelin-1(1-31) and endothelin-1 in healthy subjects andpatients with atherosclerosis

J. Cardiovasc. Pharmacol. 41(1):S83-S87, 2003

 

2) Yuichi Ozawa, Toyoshi Hasegawa, Koichiro Tsuchiya, Masanori Yoshizumi, Toshiaki Tamaki

Effect of endothelin-1(1-31) on the renal resistance vessels

J. Medical Investigation 52:87-94, 2003

 

3) Masanori Yoshizumi, Jun-ichi Abe, Koichiro Tsuchiya, Bradford C. Berk, Toshiaki Tamaki

Stress and vascular responses: Atheroprotective effect of laminar fluid shear stress in endothelial cells: Possible role of mitogen-activated protein kinases

J. Pharmacol Sci 91:172-176, 2003

 

4) 玉置俊晃「アドレナリン受容体」

玉置俊晃/吉栖正典「アンジオテンシンII 受容体」

玉置俊晃/土屋浩一郎「エンドセリン 受容体」

玉置俊晃「バゾプレッシン受容体」

麻酔管理に関連する受容体

大下修造編集 新興交易医書出版部 2003年4月20日発行

 

5) Sei H, Fujihara H, Ueta Y, Morita K, Kitahama K, Morita Y.

Single eight-hour shift of light-dark cycle increases brain-derived neurotrophic factor protein levels in the rat hippocampus

Life Sci. 73(1):53-9, 2003

 

6) Morita K, Arimochi H, Ohnishi Y.

In vitro cytotoxicity of 4-methylcatechol in murine tumor cells: induction of apoptotic cell death by extracellular pro-oxidant action

J Pharmacol Exp. Ther. 306(1):317-23, 2003

 

7) Morita K, Kuwada A, Fujihara H, Morita Y, Sei H.

Changes in the expression of steroid metabolism-related genes in rat adrenal glands during selective REM sleep deprivation

Life Sci. 72(17):1973-82, 2003

 

8) Kentaro Kogure, Koichiro Tsuchiya, Kazutoyo Abe, Michinori Akasu. Toshiaki Tamaki, Kenji Fukuzawa, Hiroshi Terada

Direct radical scavenging by the bisbenzylisoquinoline alkaloid cepharanthine

Biochem. Biophy. Acta 1622:1-5, 2003

 

9) Kazuyoshi Kirima , Koichiro Tsuchiya, Hiroyoshi Sei, Toyoshi Hasegawa, Michiyo Shikishima, Yuki Motobayashi, Kyoji Morita, Masanori Yoshizumi, Toshiaki Tamaki

Evaluation of systemic blood NO dynamics by EPR spectroscopy: HbNO as an endogenous index of NO

Am J Physiol Heart Circ Physiol. 285(2):H589-96, 2003

 

10) Toshiaki Tamaki and Masao Yoshizumi

Forum Minireview: New Methods to evaluate endothelial Function

J. Pharmacol Sci. 3:397-422, 2003

 

11) Koichiro Tsuchiya, Kazuyoshi Kirima, Masanori Yoshizumi, Toshiaki Tamaki

Evaluation of endothelial function by hemoglobin-nitric oxide complex (Hb2+-NO) using electron paramagnetic resonance (EPR) spectroscopy

J. Pharmacol Sci. 93:417-422, 2003

 

2004年(平成16年)

1) Masanori Yoshizumi, Yoshiko Fujita, Yuki Izawa, Yuki Suzaki, Moe Kyaw, Nermin Ali, Koichiro Tsuchiya, Shoji Kagami, Seiji Yano, Saburi Sone, Toshiaki Tamaki

Ebselen inhibits tumor necrosis factor-a-induced c-jun N-terminal kimase activation and adhesion molecule expression in endothelial cells

Exp. Cell Res. 292:1-10, 2004

 

2) Akira Nishiyama, Masanori Yoshizumi, Matlubur Rahman, Hiroyuki Kobori, DaleM. Seth, Akira Miyatake,Guo-Xing Zhang, Li Yao, Hirofumi Hitomi, Takatomi Shokoji, Hideyasu Kiyomoto, Shoji Kimura, Toshiaki Tamaki, Masakazu Kohno and Youichi Abe

Effects of AT1 receptor blockade on renal injury and mitogen-activated protein activity in Dahl salt-sensitive rats

Kidney International 65:972-981, 2004

 

3) Toyoshi Hasegawa, Atsushi Bando, Koichito Tsuchiya, Shinji Abe, Masumi Okamoto, Kazuyoshi Kirima,Satoru Ueno, Masanori Yoshizumi, Hitoshi Houchi, and Toshiaki Tamaki

Enzymatic and non-enzymatic formation of reactive oxygen species from 6-anilino-5,8-quinolineequinone

Biochim Biophysic. Acta 1670:19-27, 2004

 

4) Akira Nishiyama, Masanori Yoshizumi, Hirofumi Hitomi, Shoji Kagami, ShujiKondo, Akira Miyatake, Megumu Fukunaga, Toshiaki Tamaki, Hideyasu Kiyomoto,Masakazu Kohno, Takatomi Shokoji, Shoji Kimura and Youichi Abe

The SOD mimetic tempol ameliorates glomerular injury and reduces MAPK activity in Dahl salt-sensitive rats

J. Am. Soc. Nephrol 15:306-315, 2004

 

5) 吉栖正典,土屋浩一郎,玉置俊晃

フラボノイドの動脈硬化作用

食の科学ライブラリー3 食品成分のはたらき 山田耕路編 平成16年3月20日発行

 

6) Shinji Abe, Kazuyoshi Kirima, Koichiro Tsuchiya, Masumi Okamoto, Toyoshi Hasegawa, Hitoshi Houchi, Masanori Yoshizumi, and Toshiaku Tamaki

The reaction rate of edaravone ( 3-methyl-1-phenyl-2-pyrazolin-5-one(MCI-186) with hydroxyl radical

Chemical & Pharmaceutical Bulletin 52:186-191, 2004

 

7) Nermin Ali, Masanori Yoshizumi, Koichiro Tsuchiya, Moe Kyaw, Yoshiko Fujita, Yuki Izawa, Shinji Abe, Yasuhisa Kanematsu, Shoji Kagami, Toshiaki Tamaki

Ebsalen inhibits p38MAP kinase-mediated endothelial cell death by hydrogen peroxide

Eur. J. Pharmacol 485:127-135, 2004

 

8) Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Shoji Kagami, Yuki Izawa, Yoshiko Fujita, Nermin Ali, Yasuhisa Kanematsu, Kazunori Toida, Kazunori Ishimura, and Toshiaki Tamaki

Src and Cas are essentially but differentially involved in angiotensin II-stimulated migration of vascular smooth muscle cell via ERK1/2 and JNK activation

Molecular Pharmacology 65:832-841, 2004

 

9) Yuki Suzaki, Masanori Yoshizumi, Shoji Kagami, Akira Nishiyama, Yuichi Ozawa, Moe Kyaw, Yuki Izawa,Yasuhisa Kanematsu, Koichiro Tsuchiya and Toshiaki Tamaki

BMK1 is activated in glomerului of diabetic rats and in mesangial cells by high glucose condition

Kidney Inter. 65:1749-1760, 2004

 

10) Keisuke Ishizawa, Masanori Yoshizumi, Koichiro Tsuchiya, Hitoshi Houchi, Kazuo Minakuchi, Yuki Izawa, Yasuhisa Kanematsu, Shoji Kagami, Masao Hirose, Toshiaki Tamaki

Dual Effects of Endothelin-1 (1-31): Induction of Mesangial Cell Migration and Facilitation of Monocyte Recruitment through MCP-1 Production by Mesangial Cells

Hypertension Research 27:433-440, 2004

 

11)藤守義光,寺嶋吉保,玉置俊晃,森口博基,相野田紀子,樫田美雄

医療のエスノメソドロジー研究の現状と課題

徳島大学社会科学研究17 2004年2月発行

 

12) Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Yumi Izawa, Yasuhisa Kanematsu, Toshiaki Tamaki

Atheroprotective Effects of Antioxidants through the Inhibition of Mitogen-Activated Protein Kinases

Acta Pharmacologica Sinica 25:977-985, 2004

 

13) Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Yuki Izawa, Yasuhisa Kanematsu, Yoshiko Fujita,Nermin Ali, Keisuke Ishizawa, Aiko Yamauchi, Toshiaki Tamaki

Antioxidants effects of stereoisomers of N-acetylcystein(NAC), L-NAC and D-NAC on angiotensin II-stimulated MAP-kinases activation and vascular smooth muscle proliferation

J. Pharmacol. Science 95:483-486, 2004

 

14) Akira Nishiyama, Yao L, Nagai Y, Miyata K, Masanori Yoshizumi, Shoji Kagami, Kondo S, Hideyasu Kiyomoto, Shokoji T, Shoji Kimura, Kohno M, Youichi Abe

Possible Contributions of Reactive Oxygen Species and Mitogen-Activated Protein Kinase to Renal Injury in Aldosterone/Salt-Induced Hypertensive Rats

Hypertension 43(4):841-8, 2004

 

15) 吉栖正典,浩一郎,兼松康久,玉置俊晃

心筋障害作用 V. エンドセリン 薬理作用と生理作用

日本臨床 62(9):22-625, 2004

 

16) Koichiro Tsuchiya, Yoshiharu Takiguchi, Masumi Okamoto, Yuki Izawa, Yasuhisa Kanematsu, Masanori Yoshizumi, Toshiaki Tamaki

Malfunction of vascular control in lifestyle-related diseases: Formation of systemic hemoglobin-nitric oxide complex (Hb-NO) from dietary nitrite

J. Pharmacol. Science 96:395-400, 2004

 

17) Kaori Akai, Koichiro Tsuchiya, Akira Tokumura, Kentaro Kogure, Satoru Ueno, Akira Shibata, Toshiaki Tamaki, and Kenji Fukuzawa

Ability of ferric nitrilotriacetate complex with three pH-dependent conformations to induce lipid peroxidation

Free Radical Research 38:951-962, 2004

 

18) Nishiyama A, Yao L, Fan Y, Kyaw M, Kataoka N, Hashimoto K, Nagai Y, Nakamura E, Yoshizumi M, Shokoji T, Kimura S, Kiyomoto H, Tsujioka K, Kohno M, Tamaki T, Kajiya F and Abe Y.

Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferation and deformability

Hypertension 45(4):710-6, 2004

 

2005年(平成17年)

1) Masumi Okamoto, Koichiro Tsuchiya, Yasuhisa Kanematsu, Yuki Izawa, Masanori Yoshizumi, Susumu Kagawa, Toshiaki Tamaki

Nitrite-derived nitric oxide formation following ischemia-reperfusion injyury in kidney

Am. J. Physiol. Renal Physiology 288:F182-F187, 2005

 

2) Nishiyama A, Yao L, Fan Y, Kyaw M, Kataoka N, Hashimoto K, Nagai Y, Nakamura E, Yoshizumi M, Shokoji T, Kimura S, Kiyomoto H, Tsujioka K, Kohno M, Tamaki T, Kajiya F and Abe Y

Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferation and deformability

Hypertension Research 45(2):710-716, 2005

 

3) Koichiro Tsuchiya, Yasuhisa Kanematsu, Masanori Yoshizumi, Hideki Ohnishi, Kazuyoshi Kirima, Yuki Izawa, Michiyo Shikishima, Shuji Kondo, Shoji Kagami, Yasuharu Takiguchi, Toshiaki Tamaki

Nitrite is an alternative source of NO in vivo

Am J Physiology Heart Circ. Physiology 288:H2163-H2170, 2005

 

4) Yuki Izawa, Masanori Yoshizumi, Yoshiko Fujita, Nermin Ali, Yasuhisa Kanematsu, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiyuki Obata, Yousuke Ebina, Shuhei Tomita, Toshiaki Tamaki

ERK 1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells

Experimental Cell Research 308:291-299, 2005

 

5) Nermin Ali, Masanori Yoshizumi, Yoshiko Fujita, Yuki Izawa, Yasuhisa Kanematsu,Keisuke Ishizawa, Koichiro Tsuchiya, Seiji Yano, Saburo Sone, Toshiaki Tamaki.

A novel Src kinase inhibitor, M475271, inhibited VEGF-induced human umbilical vein endothelial cell proliferation and migration

J Pharm Sciences 98:130-141, 2005

 

6) 土屋浩一郎,玉置俊晃

「最近の話題」:生体内での亜硝酸由来のNO産生系

日本薬理学雑誌 125:318, 2005

 

7) 兼松康久,土屋浩一郎,玉置俊晃

生体内における亜硝酸NO産生と、その循環動態への作用検討

血管 28:39-45, 2005(若手研究者奨励賞受賞)

 

8) 藤田佳子,吉栖正典,井澤有紀,兼松康久,玉置俊晃

ヒト臍帯静脈内皮細胞(HUVEC)におけるLysophosphatidylcholine(LPC)刺激による VEGF レセプターのトランスアクチベーション

四国医学会雑誌 61:91-94, 2005(第14回徳島医学会賞受賞)

 

9) Yasumasa Ikeda, Ken-ichi Aihara, Takashi Sato, Masashi Akaike, Masanori Yoshizumi, Yuki Suzaki, Yuki Izawa, Mitsunori Fujimura, Shunji Hashizume, Midori Kato, Shusuke Yagi, Toshiaki Tamaki, Hirotaka Kawano, Toshiro Matsumoto, Hiroyuki Azuma, Shigeaki Kato, Toshio Matsumoto

Androgen receptor gene knockout male mice exhibit impaired cardiac growth and exacerbation of angiotensin II-induced cardiac fibrosis

J. Bio. Chem. 280:29661-29666, 2005

 

10) 玉置俊晃

腎臓作用薬

医科薬理学 改訂4版 9月26日発行, 2005

 

11) 田島壮一郎,土屋浩一郎,大西秀樹,兼松康久,玉置俊晃,Mason Ronald,滝口祥令

ラジカル認識抗体を用いた酸化ストレス由来プロテインラジカル検出法

日本薬理学雑誌 126(4):246-249, 2005

 

12) Keisuke Ishizawa, Yuki Izawa, Hiroyuki Ito, Chieko Miki, Kayoko Miyata, Yoshiko Fujita, Yasuhisa Kanematsu, Koichiro Tsuchiya, Toshiaki Tamaki, Akira Nishiyama, Masanori Yoshizumi

Aldosterone stimulates vascular smooth muscle cell proliferation via big mitogen-activated protein kinase 1 activation

Hypertension 46(4):1046-52, 2005

 

13) Koichiro Tsuchiya, Kaori Akai, Akira Tokumura, Shinji Abe, Toshiaki Tamaki, Yoshiharu Takiguchi, Kenji Fukuzawa.

Oxygen radical photo-induced by ferric nitrilotriacetate complex

Biochim Biophys Acta. (general subjects) 1725(1): 111-1119, 2005

 

14) Hiroyuki Sakakibara, Kaori Ishida, Yuki Izawa, Yuko Minami, Satomi Saito, Yoshichika Kawai, Veronika Butterweck, Toshiaki Tamaki, Yutaka Nakaya, Junji Terao

Effects of forced swimming stress on rat brain function (Proceeding)

J.Med Invest. 52:300-301, 2005

 

15) Hideki Arimochi, Kyoji Morita

High Salt Culture Conditions Suppress Proliferation of Rat C6 Gloma Cell by Arresting Cell-Cycle Progression at S-Phase

Journal of Molecular Neuroscience 27:293-302, 2005

 

16) Kyoji Morita, Hideaki Arimochi, Song Her

Serotonergic 5-HT2A receptor stimulation induces steroid 5α-reductase gene expression in rat C6 gloma cells via transcription factor Egr-1

Molecular Brain Research 139:193-200, 2005

 

17) 玉置俊晃

e-learning

徳島大学高度情報化基盤センター「広報」12巻, 2005

 

2006年(平成18年)

1) Yoshiko Fujita, Masanori Yoshizumi, Yuki Izawa, Nermin Ali, Yasuhisa Kanematsu, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki.

Transactivation of Flk-1/KDR by lisophosphatidylcholine induces vascular endothelial cell proliferation

Endocrinology 147(3):1377-1385, 2006

 

2) Yoshiko Fujita, Yuki Izawa, Nermin Ali, Yasuhisa Kanematsu, Koichiro Tsuchiya, Shuichi Hamano, Toshiaki Tamaki, Masanori Yoshizumi.

Pramipexole protects against H2O2-induced PC12 cell death

Naunyn-Schmiedeberg’s Arch Pharmacol. 372:257-266, 2006

 

3) Shuji Kondo, Maki Shimizu, Maki Urushihara. Koichiro Tsuchiya, Masanori Yoshizumi, Toshiaki Tamaki, Akira Nishiyama, Hiroshi Kawachi, Fujio Shimizu, Mark T. Quinn, David J. Lambeth, Shoji Kagami

Addition of the antioxidant probucol to angiotensin II type I receptor antagonist arrests progression mesangioproliferative glomerulonephritis in the rat

J Am Soc Nephrology 17:783-794, 2006

 

4) 玉置俊晃,安部陽一

レニン・アンジオテンシン系と腎血行動態:基礎

腎と透析 60:299-300, 2006

 

5) Yasuhisa kanematsu, Koichiro Tsuchiya, Hideki Ohnishi, Yuki Motobayashi, Yuki Izawa, Manabu Ishihara, Keisuke Ishizawa, Shinji Abe, Kazuyoshi Kawazoe, Toshiaki Tamaki

Effects of Angiotensin II Type 1 Receptor Blockade on the Systemic Blood NO Dynamics in L-NAME-treated Rats

Hypertens Res 29:369-374, 2006

 

6) 大西秀樹,土屋浩一郎,阿部真治,田島壮一郎,元林有紀,岡本増巳,玉置俊晃

腎虚血時における亜硝酸由来の一酸化窒素産生

腎とフリーラジカル 第8集, 2006

 

7) Shinji Abe, Hideki Ohnishi, Koichiro Tsuchiya , Yoshiharu Takiguchi, Kazuyoshi Kawazoe, Kazuo Minakuchi, Toshiaki Tamaki

Calcium and reactive oxygen species mediated zinc-induced apoptosis in PC12 cells

J. Pharmacol. Science 102:103-111, 2006

 

8) Nermin Ali, Masanori Yoshizumi, Seiji Yano, Saburo Sone, Hideki Ohnishi, Keisuke Ishizawa, Yasuhisa Kanematsu, Koichiro Tsuchiya, Toshiaki Tamaki

The novel Src kinase inhibitor M475271 inhibits VEGF-induced VE-cadherin and β-catenin phosphorylation but increases their association

J. Pharmacol. Science 102:112-120, 2006

 

9) 吉栖正典, 石澤啓介, 井澤有紀, 玉置俊晃; インスリン抵抗性による血管障害の細胞内情報伝達機構

日本薬理学雑誌, 128:147-151, 2006

 

2007年(平成19年)

1) 石澤啓介,水口和生,玉置俊晃

医療人としての薬剤師養成教育の実践

医薬ジャーナル 43(3):871, 2007

 

2) 玉置俊晃,石澤啓介,山口邦久

薬理作用から見た健康食品

四国医学雑誌 63(5,6), 2007

 

3) Yuki Izawa, Masanori Yoshizumi, Keisuke Ishizawa, Yoshiko Fujita, Shuji Kondo, Shoji Kagami, Kazuyoshi Kawazoe, Koichiro Tsuchiya, Shohei Tomita, Toshiaki Tamaki

Big mitogen-activated protein kinase 1 (BMK1)/Extracellular signal regulated kinase 5 (ERK5) is involved in platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell migration

Hypertension Research 30:1107-1117, 2007

 

2008年(平成20年)

1) 樫田美雄,岡田光弘,五十嵐素子,宮崎彩子,出口寛文,真鍋陸太郎,藤崎和彦,北村隆憲,高山智子,太田能,玉置俊晃,寺嶋吉保,阿部智恵子,島田昭仁,小泉秀樹

高等教育改革の相互行為分析―ビデオ・エスノグラフィー研究の狙いと工学部とし工学演習の実際―大学教育研究ジャーナル 5:93-104, 2008

 

2) 土屋浩一郎,玉置俊晃

酸化ストレス評価法の将来展望

最新透析医学 西沢良記編2008年7月発行:123-127, 2008

 

3) 大西秀樹,土屋浩一郎,田島壮一郎,堀ノ内裕也,福原弥生,山口邦久,石澤啓介,冨田修平,玉置俊晃

ハイドロエチジウム蛍光分析法による細胞内スーパーオキシド検出法の評価

腎とフリーラジカル 第9集:34-41, 2008

 

4) 石澤啓介,三木恵里加,石澤(井澤)有紀,大西秀樹,Narantungalag Dorjsuren,元林有紀,山口邦久,土屋浩一郎,冨田修平,玉置俊晃

オルメサルタンはPDGFによるメサンギウム細胞遊走を抑制する

腎とフリーラジカル 第9集:172-175, 2008

 

5) 土屋浩一郎,玉置俊晃

血管内皮機能と血中一酸化窒素の測定

腎と透析 65(4):530-533, 2008

 

6) Yasuhisa Kanematsu, Kunihisa Yamaguchi, Hideki Ohnishi, Yuki Motobayashi, Keisuke Ishizawa, Yuki Izawa, Kazuyoshi Kawazoe, Shuji Kondo, Shoji Kagami, Shuhei Tomita, Koichiro Tsuchiya, Toshiaki Tamaki

Dietary doses of nitrite restore circulating nitric oxide level and improve renal injury in L-NAME-induced hypertensive rats

American Journal of Physiology; Renal Physiology 295(5):1457-1462, 2008

 

7) 石澤啓介,三木恵里加,石澤(井澤)有紀,大西秀樹,Narantungalag Dorjsuren,元林有紀,山口邦久,土屋浩一郎,冨田修平,玉置俊晃

PDGFによるメサンギウム細胞遊走に対するオエウメサルタンの抑制効果とその分子機構

血管 31(2):59-64, 2008

 

8) Masahiro Watanabe, Takenori Yamamoto, Rei Kakuhata, Naoto Okada, Kazuaki Kajimoto, Naoshi Yamazaki, Masatoshi Kataoka, Yoshinobu Baba, Toshiaki Tamaki, Yasuo Shinohara

Synchronized changes in transcript levels of genes activating cold exposure-induced thermogenesis in brown adipose tissue of experimental animals

BBA Bioenergetics 1777: 104-112, 2008

 

9) 土屋浩一郎,大西秀樹,石澤啓介,山口邦久,田島壮一郎,堀ノ内裕也,玉置俊晃

ROS検出試薬・ジヒドロエチジウムの光化学反応

Pharma Merdica 26:132, 2008